KEGG   ORTHOLOGY: K23493
Entry
K23493            Tight     KO                                     
Symbol
GS
Name
geissoschizine synthase [EC:1.3.1.36]
Pathway
map00901  Indole alkaloid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00981  Geissoschizine biosynthesis, tryptophan => geissoschizine
Reaction
R03860  geissoschizine:NADP+ 4,21-oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00901 Indole alkaloid biosynthesis
    K23493  GS; geissoschizine synthase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.36  geissoschizine dehydrogenase
     K23493  GS; geissoschizine synthase
Other DBs
GO: 0047920
Genes
AG: AHK60845(GS2) AHK60846(GS1) WKU61919(GS)
Reference
PMID:24710322
  Authors
Miettinen K, Dong L, Navrot N, Schneider T, Burlat V, Pollier J, Woittiez L, van der Krol S, Lugan R, Ilc T, Verpoorte R, Oksman-Caldentey KM, Martinoia E, Bouwmeester H, Goossens A, Memelink J, Werck-Reichhart D
  Title
The seco-iridoid pathway from Catharanthus roseus.
  Journal
Nat Commun 5:3606 (2014)
DOI:10.1038/ncomms4606
  Sequence
[ag:AHK60846 AHK60845]
Reference
PMID:28827772
  Authors
Tatsis EC, Carqueijeiro I, Duge de Bernonville T, Franke J, Dang TT, Oudin A, Lanoue A, Lafontaine F, Stavrinides AK, Clastre M, Courdavault V, O'Connor SE
  Title
A three enzyme system to generate the Strychnos alkaloid scaffold from a central biosynthetic intermediate.
  Journal
Nat Commun 8:316 (2017)
DOI:10.1038/s41467-017-00154-x
  Sequence
[ag:AHK60846 AHK60845]
LinkDB

DBGET integrated database retrieval system