KEGG   ORTHOLOGY: K23694
Entry
K23694                      KO                                     
Symbol
GRAP
Name
GRB2-related adapter protein
Disease
H00605  Deafness, autosomal recessive
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified
    K23694  GRAP; GRB2-related adapter protein
Domain-containing proteins not elsewhere classified [BR:ko04990]
 Src homology (SH) domain-containing proteins
  Signal transducing adaptor proteins
   K23694  GRAP; GRB2-related adapter protein
Other DBs
GO: 0005070
Genes
HSA: 10750(GRAP)
PTR: 454496(GRAP)
PPS: 117974268(GRAP)
GGO: 101142742
PON: 100448502
PPYG: 129017741
NLE: 100596282(GRAP)
HMH: 116483178
MCC: 702473(GRAP)
MCF: 102126820(GRAP)
MTHB: 126939052
MNI: 105493350(GRAP)
CSAB: 103242505(GRAP)
CATY: 105576900(GRAP)
PANU: 101024992(GRAP)
TGE: 112610021
MLEU: 105534650(GRAP)
RRO: 104655564(GRAP)
RBB: 108516957(GRAP)
PTEH: 111528159(GRAP)
CANG: 105520991(GRAP)
CJC: 100392054(GRAP)
SBQ: 101049383(GRAP)
CIMI: 108293500
ANAN: 105730711(GRAP)
CSYR: 103252627(GRAP)
MMUR: 105862014(GRAP)
LCAT: 123621108
PCOQ: 105823460(GRAP)
OGA: 100962265(GRAP)
MMU: 71520(Grap)
MCAL: 110305267
MPAH: 110331405(Grap)
RNO: 363616(Grap)
MCOC: 116077111
ANU: 117710805
ASYL: 127693515
MUN: 110549804
CGE: 100750533
MAUA: 101835140
PROB: 127219163
PLEU: 114682967
MORG: 121456711
MFOT: 126514701
AAMP: 119811718
NGI: 103728113(Grap)
HGL: 101721246(Grap)
CPOC: 100727005
CCAN: 109699723(Grap)
DORD: 105985839
DSP: 122103330
PLOP: 125366237
NCAR: 124981008
MMMA: 107157141
ITI: 101971396
OPI: 101532742
TUP: 102494080(GRAP)
GVR: 103607787(GRAP)
CFA: 489534
CLUD: 112647270
VVP: 112924948(GRAP)
VLG: 121499766
NPO: 129496659(GRAP)
AML: 100474815(GRAP)
UMR: 103658503
UAH: 113271280(GRAP)
UAR: 123779731
ELK: 111139239 111139254
LLV: 125086923
MPUF: 101673383
MNP: 132004214(GRAP)
MLK: 131815511(GRAP)
NVS: 122906875
ORO: 101380319
EJU: 114198181
ZCA: 113939256
MLX: 118000130(GRAP)
NSU: 110584645
LWW: 102732449(GRAP)
FCA: 101085758(GRAP)
PYU: 121015823
PCOO: 112857066
PBG: 122485031
PVIV: 125151374(GRAP)
LRUF: 124519458
LGF: 123603102
AJU: 106981438
PTG: 102954649(GRAP)
PPAD: 109245789
PUC: 125926951
PLEZ: 122206112
HHV: 120228803
BTA: 534491(GRAP)
BOM: 102271469(GRAP)
BIU: 109573264(GRAP)
BBUB: 102406110
BBIS: 104990857
CHX: 102190908(GRAP)
OAS: 101110605(GRAP)
BTAX: 128065243(GRAP)
CSUM: 138083979(GRAP)
ODA: 120867402
CCAD: 122444115
MREE: 136150065(GRAP)
OVR: 110151001(GRAP)
MBEZ: 129544210(GRAP)
SSC: 100511593(GRAP)
CFR: 102505324(GRAP)
CBAI: 105083670
CDK: 105100562(GRAP)
VPC: 102535039(GRAP)
BACU: 103003276(GRAP)
BMUS: 118887520
LVE: 103079454(GRAP)
OOR: 101284061(GRAP)
LALB: 132510697(GRAP)
DLE: 111167689(GRAP)
PCAD: 102981784 112065965
PSIU: 116746076(GRAP)
NASI: 112404941(GRAP)
ECB: 100050401
EAI: 106837918
MYB: 102257936(GRAP)
MYD: 102770758(GRAP)
MMYO: 118649404
MLF: 102432398(GRAP)
MDT: 132217933(GRAP)
MYUM: 138993835(GRAP)
PKL: 118726745
EFUS: 103299362(GRAP)
MNA: 107524570
DRO: 112308434(GRAP)
SHON: 119002715
AJM: 119062275(GRAP)
PDIC: 114515138
PHAS: 123809392
MMF: 118641243
PPAM: 129068688(GRAP)
HAI: 109390347(GRAP)
RFQ: 117012997(GRAP)
PALE: 102897744
PGIG: 120589846
PVP: 105291316
RAY: 107511076
TOD: 119231966(GRAP)
SARA: 101549999(GRAP)
SFUM: 130043452(GRAP)
SETR: 126013768(GRAP)
LAV: 100671605(GRAP)
TMU: 101347766
ETF: 101648799
DNM: 101430588
MDO: 100011892(GRAP)
GAS: 123250522
SHR: 100917489(GRAP)
AFZ: 127561409
PCW: 110220512(GRAP)
TVP: 118859156
PBRV: 138158886(GRAP)
OAA: 100079295
TACU: 119942617
GGA: 416523(GRAP)
PCOC: 116237400(GRAP)
MGP: 104913407(GRAP)
CJO: 107320767(GRAP)
TPAI: 128079119(GRAP)
LMUT: 125700749
NMEL: 110406135(GRAP)
APLA: 101801498
ACYG: 125183235(GRAP)
CATA: 118256358(GRAP)
AFUL: 116495274(GRAP)
TGU: 100224167(GRAP)
LSR: 110481774(GRAP)
SCAN: 103817588(GRAP)
PMOA: 120513163
OTC: 121334536
PRUF: 121350856
ATRC: 139597983(GRAP)
GFR: 102042983(GRAP)
FAB: 101817481(GRAP)
OMA: 130259194(GRAP)
PHI: 102099448(GRAP)
PMAJ: 107210952(GRAP)
CCAE: 111936155(GRAP)
CCW: 104684765
CBRC: 103615384
ACOE: 138118950(GRAP)
ETL: 114065962(GRAP)
ZAB: 102067753
ZLE: 135454111(GRAP)
ACHL: 103798685(GRAP)
SVG: 106864760(GRAP)
MMEA: 130582536(GRAP)
HRT: 120759659(GRAP)
SATI: 136367791(GRAP)
CCIC: 134050531(GRAP)
FPG: 101917782(GRAP)
FCH: 102056143(GRAP)
NNT: 104410842(GRAP)
SHAB: 115607285(GRAP)
ACUN: 113485652(GRAP)
TALA: 116963514
ACHC: 115335948
HLE: 104833623(GRAP)
AGEN: 126034120
HHAR: 128134632(GRAP)
GCL: 127022673
CSTI: 104556714
LDI: 104351740
MNB: 103774062
DPUB: 104296770(GRAP)
PPUS: 135180789(GRAP)
AVIT: 104277770(GRAP)
BRHI: 104492223(GRAP)
EGZ: 104135752
NNI: 104015129(GRAP)
PADL: 103921421(GRAP)
AFOR: 103904917(GRAP)
CBOY: 140658992(GRAP)
CLV: 102095951(GRAP)
MUI: 104539936(GRAP)
CMAC: 104480752
CUCA: 104060388(GRAP)
TEO: 104375772
BREG: 104642279(GRAP)
OHA: 104327456(GRAP)
ACAR: 104529040(GRAP)
CPEA: 104394016(GRAP)
CVF: 104289577(GRAP)
RTD: 128914360(GRAP)
CRID: 134519622(GRAP)
AROW: 112974283(GRAP)
NPD: 112959987(GRAP)
TGT: 104567394(GRAP)
DNE: 112980399(GRAP)
SCAM: 104141202
ASN: 102386178(GRAP)
AMJ: 102577011(GRAP)
CPOO: 109314653(GRAP)
GGN: 109294368(GRAP)
PSS: 102462646(GRAP)
CMY: 102941632
CCAY: 125643800
DCC: 119862958
CPIC: 101946375
TST: 117884296(GRAP)
CABI: 116814826(GRAP)
MRV: 120373735
ACS: 100552421(grap)
ASAO: 132782103(GRAP)
PVT: 110084711 110090790
SUND: 121914188
PBI: 103063647(GRAP)
PMUR: 107289140(GRAP)
CTIG: 120319268
PGUT: 117679509(GRAP)
APRI: 131185072(GRAP)
PTEX: 113438854(GRAP)
NSS: 113422350(GRAP)
VKO: 123024927
PMUA: 114584720(GRAP)
PRAF: 128401782(GRAP)
ZVI: 118092774(GRAP)
HCG: 128336858(GRAP)
GJA: 107108698(GRAP)
EMC: 129340254(GRAP)
XLA: 108701658(grap.L) 108703215(grap.S)
XTR: 100127598(grap)
NPR: 108793671(GRAP)
RTEM: 120943234
BBUF: 121007512
BGAR: 122945586
PWL: 138261298(GRAP)
MUO: 115476333(GRAP)
GSH: 117369317(GRAP)
DRE: 553596(grapa) 555184(grapb)
SRX: 107720042 107722955 107725346 107737776
SANH: 107654542 107674739 107701786 107702513
SGH: 107564666 107581733 107590757 107592716
CCAR: 109053958 109057445(grapb) 109063300 109100321
CAUA: 113044332 113044549 113050397 113050407 113078094
CGIB: 127948585 127951812 127953634
PTET: 122341938(grapa) 122347141(grapb) 122354586
LROH: 127162592(grapb) 127163241(grapa)
OMC: 131536436(grapa) 131544659(grapb)
PPRM: 120460476(grapb) 120489906(grapa)
RKG: 130091050(grapb) 130094984(grapa)
MAMB: 125269232(grapa) 125272688(grapb)
CIDE: 127508598 127521435
CERY: 137017756(grapa) 137032664(grapb)
MASI: 127444410 127445436 127450915 127451202
TROS: 130552622(grapb) 130561547(grapa)
TDW: 130426870(grapa) 130432818(grapb)
MANU: 129432977(grapa) 129444945(grapb)
PDAB: 135735776(grapb) 135737654 135748261
IPU: 108257491(grapa) 108258884(grapb)
IFU: 128600635(grapa) 128602052(grapb)
PHYP: 113535499 113536316
SMEO: 124376405(grapa) 124378217(grapb)
TFD: 113637344(grapb) 113644012(grapa)
TVC: 132837417(grapa) 132839355(grapb)
CGAR: 128506758(grapb) 128519503(grapa)
NGRA: 132866650(grapb) 132900740(grapa)
TRN: 134307193(grapa) 134329325(grapb)
AMEX: 103040219(grapa) 103047542(grapb)
CMAO: 118798108(grapb) 118805688(grapa)
EEE: 113584971
CHAR: 105899926(grapa)
SPIL: 134076342(grapa)
TRU: 101062391
TFS: 130514958(grapa) 130528019
TNG: GSTEN00008087G001 GSTEN00021849G001
LCO: 104925613 104929960
NCC: 104958164
TBEN: 117481657 117493651(grapa)
CGOB: 115011988 115012384
PGEO: 117448111 117451150(grapa)
GACU: 117552793 117552802 117556201
EMAC: 134864599 134878452(grapa)
ELY: 117255377 117268377(grapa)
EFO: 125879263(grapa) 125885705
PLEP: 121942434 121956056(grapa)
SLUC: 116057221 116065406(grapa)
ECRA: 117954223 117957496(grapa)
ESP: 116702460 116705414
PFLV: 114566406 114570384
GAT: 120824930 120828176(grapa)
PPUG: 119217372 119220954(grapa)
AFB: 129096316 129098970(grapa)
CLUM: 117734532 117735261(grapa)
PSWI: 130189287(grapa) 130189931
CANA: 137786983(grapa) 137793151
CVE: 137874292 137885015
MSAM: 119886061(grapa) 119898763
SCHU: 122874060
CUD: 121503462(grapa)
SPUL: 138595217 138604312(grapa)
LMIX: 132953980(grapa) 132954613
ALAT: 119014121(grapa) 119024288
ASTR: 137610321(grapa)
MZE: 101475115 101484535
ONL: 100690405 100696217
OAU: 116312356 116333262(grapa)
OLA: 101160815 101166194
OML: 112137267(grapb) 112146899(grapa)
CSAI: 133421635(grapa) 133451886
XMA: 102227965 102233710
XCO: 114144852 114159741
XHE: 116719528 116735188
PRET: 103460724 103469145 108165995
PFOR: 103131885 103151813
PLAI: 106942991 106951956(grap)
PMEI: 106911803 106914541(grap)
GAF: 122822301(grapa) 122829329
PPRL: 129353730
CVG: 107086417 107088092
CTUL: 119783656 119793527(grapa)
GMU: 124862384 124864621 124868705
NFU: 107376709(grap) 107388770
KMR: 108242945(grapa) 108248562
ALIM: 106516533 106519652
NWH: 119422177(grapa) 119422895
AOCE: 111565347(grapa) 111579496
EJA: 138198347(grapa) 138209410
BFRE: 138615857 138627566(grapa)
MCEP: 124998477(grapa) 125004553
CSEM: 103383265 103393188
POV: 109639513 109639591
SSEN: 122785022(grapa)
SSOE: 131474911(grapa)
HHIP: 117765243 117766771(grapa)
HSP: 118115581 118123746(grapa)
PPLT: 128433497 128458166(grapa)
SMAU: 118288665(grapa) 118312572
LCF: 108881065(grapa) 108888459
SDU: 111216690 111230241
SLAL: 111647500 111663259 111670533
XGL: 120800458 120807376(grapa)
HCQ: 109510987 109514920
SSCV: 125968371 125983543(grapa)
SBIA: 133506311 133514243(grapa)
PEE: 133403734 133414867(grapa)
PTAO: 133466101(grapa) 133477251
BPEC: 110160580 110167565
ENY: 140357928(grapa) 140378176
MALB: 109958855 109968209
BSPL: 114852595 114860593(grapa)
SJO: 128379169(grapa) 128380088
SSCO: 133994876 134000085(grapa)
GMH: 115533874 115540306
SASA: 106592541 106600772 106602037
STRU: 115184244
OTW: 112240575(grapa) 121845325
OMY: 118947120(grapa) 118948936 118948948
OGO: 124021089(grapa) 124024244
OKI: 116360016 116361444 116364080 116371088
OKE: 127920229 127924843
OMM: 135535920 135535932 135538752 135538776
OCLA: 139394189 139398791 139422371 139424109 139424185
SNH: 120040522
CCLU: 121537567
ELS: 105008029 105030332
SFM: 108926070 108941747
PKI: 111845582
AANG: 118217356 118220640
AROT: 135243421 135248235
CCOG: 133115338 133121900
LOC: 102684352(grap)
PSPA: 121294155 121300790
ARUT: 117417789 117431032
PSEX: 120542882
CMK: 103187097
RTP: 109920905
CPLA: 122560525
HOC: 132825151
LERI: 129706979
SMM: Smp_044530
OVI: T265_13452
EGL: EGR_09709
DGT: 114538307
AQU: 105313392
 » show all
Reference
PMID:8647802
  Authors
Feng GS, Ouyang YB, Hu DP, Shi ZQ, Gentz R, Ni J
  Title
Grap is a novel SH3-SH2-SH3 adaptor protein that couples tyrosine kinases to the Ras pathway.
  Journal
J Biol Chem 271:12129-32 (1996)
DOI:10.1074/jbc.271.21.12129
  Sequence
[hsa:10750]
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