KEGG ORTHOLOGY: K23882

ORTHOLOGY: K23882

Entry

K23882                      KO

Symbol

CISD2

Name

CDGSH iron-sulfur domain-containing protein 2

Disease

H00854

Wolfram syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K23882  CISD2; CDGSH iron-sulfur domain-containing protein 2
Membrane trafficking [BR:ko04131]
Autophagy
  Other autophagy associated proteins
   Others
    K23882  CISD2; CDGSH iron-sulfur domain-containing protein 2

Genes

HSA:	493856(CISD2)

PTR:	100609495(CISD2)

PPS:	103783527(CISD2)

GGO:	101153815(CISD2)

NLE:	100594309(CISD2)

HMH:	116471428 116482845(CISD2)

MCC:	100429989(CISD2)

MCF:	101926114(CISD2)

MTHB:

126955402

MNI:	105486332(CISD2)

CSAB:

103236055(CISD2)

CATY:

105571381(CISD2)

PANU:

101002925(CISD2) 101013299

TGE:	112624443(CISD2)

MLEU:

105548322(CISD2)

RRO:	115892795(CISD2)

RBB:	108532806(CISD2)

TFN:	117085722(CISD2)

PTEH:

111540011 111547980(CISD2)

CANG:

105512683(CISD2)

CJC:	100394333(CISD2)

CIMI:

108289244(CISD2)

CSYR:

103255527(CISD2)

MMUR:

105867072 105874831(CISD2)

LCAT:

123627210(CISD2) 123628435

PCOQ:

105819190(CISD2)

OGA:	100952437(CISD2)

MMU:	67006(Cisd2)

MCAL:

110290681(Cisd2)

MPAH:

110320233(Cisd2)

RNO:	295457(Cisd2)

MCOC:

116093822(Cisd2)

ANU:	117707007(Cisd2)

MUN:	110558606(Cisd2)

CGE:	113833500(Cisd2)

MAUA:

101840040(Cisd2)

PROB:

127222981(Cisd2)

PLEU:

114683159(Cisd2)

MORG:

121446475(Cisd2)

MFOT:

126500502

AAMP:

119800959(Cisd2)

NGI:	103728030(Cisd2)

HGL:	101724878(Cisd2)

CPOC:

100716445(Cisd2)

CCAN:

109682964(Cisd2)

DORD:

105991230(Cisd2)

DSP:	122127105(Cisd2)

PLOP:

125341638(Cisd2) 125364682

NCAR:

124994349

MMMA:

107141355(Cisd2)

OCU:

100345441

OPI:	101529721(CISD2)

TUP:	102488251(CISD2)

GVR:	103597091(CISD2)

CFA:	106558129(CISD2)

CLUD:

112644577(CISD2)

VVP:	112908350(CISD2)

VLG:	121492421(CISD2)

NPO:	129521128(CISD2)

AML:	100471089(CISD2)

UMR:	121101426(CISD2)

UAH:	113263095(CISD2)

UAR:	123789001(CISD2)

ELK:

111156271

LLV:

125093228

MPUF:

101678538(CISD2)

MNP:	132001848(CISD2)

MLK:	131829823(CISD2)

NVS:	122889326(CISD2)

ORO:	101374410(CISD2)

EJU:	114199335(CISD2)

ZCA:	113924589(CISD2)

MLX:	118027053(CISD2)

NSU:	110572152(CISD2)

LWW:	115940685(CISD2)

FCA:	101094592(CISD2)

PYU:	121031802(CISD2)

PCOO:

112858626(CISD2)

PBG:	122477951(CISD2)

PVIV:

125163779(CISD2)

LRUF:

124520506

PTG:	102950883(CISD2)

PPAD:

109247462(CISD2)

PUC:

125923695

AJU:

106984709

HHV:	120222815(CISD2)

BTA:	781260(CISD2)

BOM:	102285353(CISD2)

BIU:	109560291(CISD2)

BBUB:

102402319(CISD2)

BBIS:

104994631(CISD2)

CHX:	102181936(CISD2)

OAS:	101106939(CISD2)

BTAX:

128049719(CISD2) 128056514

ODA:	120861879(CISD2)

CCAD:

122422029(CISD2) 122449975

MBEZ:

129561594(CISD2)

SSC:	100524158(CISD2)

CFR:	102515716(CISD2)

CBAI:

105067918(CISD2)

CDK:	105089565(CISD2)

VPC:	102530516(CISD2)

BACU:

103000897(CISD2)

BMUS:

118895864(CISD2)

LVE:	103070397(CISD2)

OOR:	101272860 101281119(CISD2)

DLE:	111179113(CISD2)

PCAD:

102984996(CISD2)

PSIU:

116754161(CISD2)

NASI:

112393807(CISD2)

ECB:	100630458(CISD2)

EPZ:	103566749(CISD2)

EAI:	106847252(CISD2)

MYB:	102252862(CISD2)

MYD:	102754102(CISD2)

MMYO:

118671955(CISD2)

MLF:	102436892(CISD2)

PKL:	118703429(CISD2)

EFUS:

103299781(CISD2)

MNA:	107545513(CISD2)

DRO:	112317795(CISD2)

SHON:

118977177(CISD2)

AJM:	119065767(CISD2)

PDIC:

114492885(CISD2)

PHAS:

123806814(CISD2)

MMF:	118641854(CISD2)

PPAM:

129085318(CISD2)

HAI:	109372536(CISD2)

RFQ:	117022028(CISD2)

PALE:

102882164(CISD2)

PGIG:

120591141(CISD2)

PVP:	105293025(CISD2)

RAY:	107517895(CISD2)

MJV:	108393457(CISD2)

TOD:	119243676(CISD2)

SARA:

101550365(CISD2)

SETR:

126008786 126020926 126027930(CISD2)

LAV:	100677272(CISD2)

TMU:	101351437 101359986

ETF:	101640891(CISD2)

DNM:	101428008(CISD2)

MDO:	100012196(CISD2)

GAS:	123251982(CISD2)

SHR:	100931084(CISD2)

AFZ:

127541080

PCW:	110223049(CISD2)

OAA:	114815464(CISD2)

GGA:	422714(CISD2)

PCOC:

116238884(CISD2)

MGP:	100547320(CISD2)

CJO:	107313666(CISD2)

TPAI:

128080687(CISD2)

LMUT:

125692700(CISD2)

NMEL:

110398433(CISD2)

APLA:

101790081(CISD2)

ACYG:

106045308(CISD2)

CATA:

118243584(CISD2)

AFUL:

116488713(CISD2)

TGU:	105759200(CISD2)

LSR:	110471157(CISD2)

SCAN:

103826023(CISD2)

PMOA:

120498826(CISD2)

OTC:	121346592(CISD2)

PRUF:

121362645(CISD2)

GFR:	102036457(CISD2)

OMA:	130252134(CISD2)

PHI:	102107097(CISD2)

PMAJ:

107202726(CISD2)

CCAE:

111927745(CISD2)

CCW:	104697286(CISD2)

CBRC:

103617383(CISD2)

ETL:	114068169(CISD2)

ZAB:	102061778(CISD2)

ACHL:

103809641(CISD2)

SVG:	106852549(CISD2)

MMEA:

130584266(CISD2)

HRT:	120753466(CISD2)

FPG:	101919661(CISD2)

FCH:	102049115(CISD2)

CLV:	102085720(CISD2)

EGZ:	104127824(CISD2)

NNI:	104021323(CISD2)

PCRI:

104038689(CISD2)

PLET:

104622206(CISD2)

EHS:	104515253(CISD2)

PCAO:

104052929(CISD2)

ACUN:

113479678(CISD2)

TALA:

104365639(CISD2)

PADL:

103919525(CISD2)

AFOR:

103894218(CISD2)

ACHC:

115341625(CISD2)

HALD:

104318260(CISD2)

HLE:	104843326(CISD2)

AGEN:

126044685

GCL:

127015667

CCRI:

104157051(CISD2)

CSTI:

104552618(CISD2)

CMAC:

104478119(CISD2)

MUI:	104545541(CISD2)

BREG:

104637208(CISD2)

FGA:	104072276(CISD2)

GSTE:

104263202(CISD2)

LDI:	104342110(CISD2)

MNB:	103770971(CISD2)

OHA:	104331715(CISD2)

NNT:	104406713(CISD2)

SHAB:

115610516(CISD2)

DPUB:

104307768(CISD2)

PGUU:

104460711(CISD2)

ACAR:

104520148(CISD2)

AVIT:

104269625(CISD2)

CVF:	104286883(CISD2)

RTD:	128909874(CISD2)

CUCA:

104068739(CISD2)

TEO:	104375936(CISD2)

BRHI:

104502214(CISD2)

AAM:	106491829(CISD2)

AROW:

112972196(CISD2)

NPD:	112957255(CISD2)

DNE:	112988422(CISD2)

SCAM:

104153497(CISD2)

ASN:	102369072(CISD2)

AMJ:	102559029(CISD2)

CPOO:

109322169(CISD2)

GGN:	109303903(CISD2)

PSS:	102456140(CISD2)

CMY:	102943977(CISD2)

CCAY:

125635346(CISD2)

DCC:	119854795(CISD2)

CPIC:

101944352(CISD2)

TST:	117877853(CISD2)

CABI:

116826286(CISD2)

MRV:	120406180(CISD2)

ASAO:

132776957(CISD2)

PVT:	110085336(CISD2)

SUND:

121931872(CISD2)

PBI:	103050463(CISD2)

PMUR:

107299041(CISD2) 107299051

CTIG:

120311331 120311332

PGUT:

117679896(CISD2) 117679897

APRI:

131203417 131203420

PTEX:

113434815(CISD2) 113452664

NSS:	113415349(CISD2) 113415350

VKO:	123022965(CISD2)

PMUA:

114603895(CISD2)

PRAF:

128421310(CISD2)

ZVI:	118084408(CISD2)

HCG:	128327418(CISD2)

GJA:	107105755(CISD2)

STOW:

125440101(CISD2)

EMC:	129336734(CISD2)

XLA:	398808(cisd2.L) 447022(cisd2.S)

XTR:	496970(cisd2)

NPR:	108789060(CISD2)

RTEM:

120918349(CISD2)

BBUF:

120989862(CISD2)

BGAR:

122944250 122944338(CISD2)

MUO:	115461154(CISD2)

GSH:	117365904(CISD2)

DRE:	393354(cisd2)

SRX:	107730531 107746991

SANH:

107664550(cisd2)

SGH:	107552739 107556804

CCAR:

109101076 109101077

CAUA:

113070208 113095150

CGIB:

127949351 128017368

PTET:

122347337(cisd2)

LROH:

127166178(cisd2)

OMC:	131530451(cisd2)

PPRM:

120491475(cisd2)

RKG:	130072008(cisd2)

MAMB:

125272243(cisd2)

CIDE:

127514995

MASI:

127444408 127444612

TROS:

130552685(cisd2)

TDW:	130409512(cisd2)

MANU:

129444259(cisd2)

IPU:

108260528

IFU:	128604381(cisd2)

PHYP:

113545779(cisd2)

SMEO:

124381649(cisd2)

TFD:	113649947(cisd2)

TVC:	132860491(cisd2)

AMEX:

103046002(cisd2)

CMAO:

118816625(cisd2)

EEE:	113584736(cisd2)

CHAR:

105908537(cisd2)

TRU:	101071524(cisd2)

TFS:	130526713(cisd2)

TNG:	GSTEN00019989G001

LCO:

104928188

NCC:	104953006(cisd2)

TBEN:

117474623(cisd2)

CGOB:

115009934(cisd2)

PGEO:

117443342(cisd2)

GACU:

117546274(cisd2)

EMAC:

134864475(cisd2)

ELY:	117255326(cisd2)

EFO:	125885974(cisd2)

PLEP:

121942297(cisd2)

SLUC:

116034252(cisd2)

ECRA:

117955824(cisd2)

ESP:	116699746(cisd2)

PFLV:

114545506(cisd2)

GAT:	120825215(cisd2)

PPUG:

119218230(cisd2)

AFB:	129095600(cisd2)

CLUM:

117733974(cisd2)

PSWI:

130191634(cisd2)

MSAM:

119899004(cisd2)

CUD:	121508484(cisd2)

ALAT:

119020135(cisd2)

MZE:	101482311(cisd2)

ONL:	100710430(cisd2)

OAU:	116331390(cisd2)

OLA:	101158419(cisd2)

OML:	112156911(cisd2)

CSAI:

133459736(cisd2)

XMA:	102235582(cisd2)

XCO:	114144998(cisd2)

XHE:	116720381(cisd2)

PRET:

103467412(cisd2)

PFOR:

103137870(cisd2)

PLAI:

106949933(cisd2)

PMEI:

106928940(cisd2)

GAF:	122829969(cisd2)

PPRL:

129366977(cisd2)

CVG:	107099504(cisd2)

CTUL:

119771864(cisd2)

GMU:	124868989(cisd2)

NFU:	107375230(cisd2)

KMR:	108231749(cisd2)

ALIM:

106517155(cisd2)

NWH:	119408093(cisd2)

AOCE:

111567770(cisd2)

MCEP:

125003953(cisd2)

CSEM:

103383845(cisd2)

POV:	109637864(cisd2)

SSEN:

122771254(cisd2)

HHIP:

117760476(cisd2)

HSP:	118116905(cisd2)

SMAU:

118313247(cisd2)

LCF:

108896600

SDU:	111231410(cisd2)

SLAL:

111664035(cisd2)

XGL:	120800248(cisd2)

HCQ:	109519888(cisd2)

SSCV:

125968665

SBIA:

133506121(cisd2)

PEE:	133403890(cisd2)

PTAO:

133477487(cisd2)

BPEC:

110165357(cisd2)

MALB:

109961295(cisd2)

BSPL:

114852733(cisd2)

SJO:	128372244(cisd2)

SASA:

100195868(cisd2) 106602754(CISD2)

STRU:

115192030 115202080

OTW:	112231709 112234419

OMY:	110497513 110534324(cisd2)

OGO:	124001511 124012695

ONE:	115137256 115145825

OKI:	109894196 109901061

OKE:	118362916 118395354(cisd2)

SALP:

111971558 112080657

SNH:	120034936 120052779(cisd2)

CCLU:

121547200

ELS:	105027540(cisd2)

SFM:	108924593(cisd2)

PKI:	111837363(cisd2)

AANG:

118227576(cisd2)

LOC:	102683858(cisd2)

PSPA:

121296350 121321931(cisd2)

ARUT:

117408779 117421384 117972471

PSEX:

120532819(cisd2)

LCM:	102345822(CISD2)

CMK:	103177628(cisd2)

RTP:	109937307(cisd2)

CPLA:

122539552(cisd2)

HOC:	132833390(cisd2)

LERI:

129702245(cisd2)

PMRN:

116950934(CISD2)

LRJ:	133354523(CISD2)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

AJC:

DME:	Dmel_CG1458(Cisd2)

DER:

6554950

DSE:

6612676

DSI:	Dsimw501_GD17906(Dsim_GD17906)

DYA:	Dyak_GE10465

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:	6643216 6649793

DGR:

6569745

DMO:	Dmoj_GI10402

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:

AOQ:

TDA:

MDE:	101900776 131806434

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

CQU:	CpipJ_CPIJ011511

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:	115233154 115233157

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_208951

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:	119840475 119840487

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:	105385946 105388710

PGW:

CFEL:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:	103522210 103522219 108254084

CLEC:

HHAL:

NLU:

HVI:

MQU:

PHU:	Phum_PHUM407700

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

FCD:

PCHN:

EAF:

LSM:	121121827 121125414

TCF:

131886226

PPOI:

119104253

PMEO:

129591570

CEL:	CELE_W02B12.15(cisd-1)

CBR:

CBG_02885

CRQ:	GCK72_005341

HRO:	HELRODRAFT_66424

LGI:	LOTGIDRAFT_216266

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:	124280528 124282262 124282265

CRG:

CVN:

CANU:

OED:

MYI:

PMAX:

MMER:

RPHI:

DPOL:

OBI:

OSN:

LAK:	106161326 106166640

SMM:	Smp_082570

SHX:	MS3_00009220(CISD1)

OVI:	T265_03404

EGL:

NVE:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

TAD:	TRIADDRAFT_21706

AQU:

100631667

ATH:	AT5G51720(NEET)

ALY:

9301949

CRB:

17875348

CSAT:

104725675 104726446 104761172

EUS:	EUTSA_v10015074mg

BRP:

103832889

BNA:	106352221 106423905

BOE:

RSZ:

THJ:

CPAP:

CIT:

CIC:	CICLE_v10006560mg

PVY:

MINC:

TCC:

GRA:

GHI:	107904634 107923172

GAB:

108456095

HSYR:

120140554

DZI:	111288410 111289358 111290249

EGR:

104424323

GMX:	100306446 100783951

GSJ:	114367040 114389664

PVU:	PHAVU_004G125800g

VRA:

VAR:

VUN:

VUM:

APRC:

MTR:

TPRA:

CAM:

PSAT:

VVO:	131633386 131647631

LJA:	Lj2g3v0484940.1(Lj2g3v0484940.1)

ADU:

107466904

AIP:

107616557

AHF:	112711730 112779358

LANG:

109355481

PCIN:

129292623

QSA:	O6P43_005493

FVE:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:

MSYL:

PXB:	103935462 103941248

ZJU:

MNT:

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

JCU:

HBR:

MESC:

POP:	7476772 7482173

PEU:	105129576 105137580

PALZ:

JRE:

CILL:

CAVE:

QSU:

QLO:

TWL:	119984570 120004231

VVI:

VRI:

SLY:

SPEN:

SOT:

SSTN:

SDUL:

CANN:

LBB:	132631783 132633995

NTA:	107790463 107803753

NSY:

NTO:

NAU:

INI:

ITR:

SIND:

OEU:

EGT:

SSPL:

SMIL:

APAN:

HAN:

ECAD:

LSV:

CCAV:

DCR:

CSIN:

RVL:

AEW:

BVG:

SOE:

CQI:	110697163 110729764 110738531

ATRI:

MOF:

NNU:

MING:

TSS:

PSOM:

OSA:

DOSA:

Os07t0467200-01(Os07g0467200)

OBR:

OGL:

BDI:

ATS:

TDC:	119302461 119311132

TAES:

TUA:

LPER:

LRD:

SBI:

ZMA:

SITA:

SVS:

PVIR:

PHAI:

PDA:	103716886 120110740

EGU:

105054172

MUS:

103976162

ZOF:	121992876 121996856 122024493 122037333

DCT:

PEQ:

AOF:

MSIN:

NCOL:

ATR:

PPP:	112276223 112276670

CRE:	CHLRE_01g050550v5

MNG:

MNEG_7424

CVR:	CHLNCDRAFT_138123

BZE:	COCCADRAFT_58209

BOR:	COCMIDRAFT_61157

PGR:	PGTG_05772

MBR:	MONBRDRAFT_15675

SRE:	PTSG_02499

PIF:	PITG_17244

PSOJ:

PHYSODRAFT_353334

SPAR:

SPRG_15693

» show all

Reference

PMID:17846994

Authors

Amr S, Heisey C, Zhang M, Xia XJ, Shows KH, Ajlouni K, Pandya A, Satin LS, El-Shanti H, Shiang R

Title

A homozygous mutation in a novel zinc-finger protein, ERIS, is responsible for Wolfram syndrome 2.

Journal

Am J Hum Genet 81:673-83 (2007)
DOI:10.1086/520961

Sequence

[hsa:493856]

LinkDB

DBGET integrated database retrieval system