KEGG ORTHOLOGY: K24230

ORTHOLOGY: K24230

Entry

K24230                      KO

Symbol

CFAP300

Name

cilia- and flagella-associated protein 300

Disease

H00564

Primary ciliary dyskinesia

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins
    K24230  CFAP300; cilia- and flagella-associated protein 300
Cilium and associated proteins [BR:ko03037]
Motile cilia and associated proteins
  Dynein assembly factors
   K24230  CFAP300; cilia- and flagella-associated protein 300

Genes

HSA:	85016(CFAP300)

PTR:	451505(CFAP300)

PPS:	100972111(CFAP300)

GGO:	101125393(CFAP300)

PON:	100456517(CFAP300)

PPYG:

129007710(CFAP300)

NLE:	100607269(CFAP300)

HMH:	116476856(CFAP300)

SSYN:

129479557(CFAP300)

MCC:	100425161(CFAP300)

MCF:	102133580(CFAP300)

MTHB:

126936008

MNI:	105493723(CFAP300)

CSAB:

103248329(C1H11orf70)

CATY:

105591398

PANU:

101025442(CFAP300)

TGE:	112606465(CFAP300)

MLEU:

105542729

RRO:	104674654(CFAP300)

RBB:	108514064(CUNH11orf70)

TFN:	117080872(CFAP300)

PTEH:

111539974(CFAP300)

CANG:

105500930

CJC:	100394777(CFAP300)

SBQ:

101044468

CIMI:

108307643(CFAP300)

ANAN:

105719099(CFAP300)

CSYR:

103260696(CUNH11orf70)

MMUR:

105874577(C5H11orf70)

LCAT:

123641915(CFAP300)

PCOQ:

105822217

OGA:	100948649(CUNH11orf70)

MMU:	234912(Cfap300)

MCAL:

110301460(Cfap300)

MPAH:

110328250(C10H11orf70)

RNO:	654482(Cfap300)

MCOC:

116073377(Cfap300)

ANU:	117699620(Cfap300)

ASYL:

127689444(Cfap300)

MUN:	110553760(Cfap300)

CGE:	100756887(Cfap300)

MAUA:

101836217(Cfap300)

PROB:

127233577(Cfap300)

PLEU:

114708011(Cfap300)

MORG:

121451864(Cfap300)

MFOT:

126513712

AAMP:

119809882(Cfap300)

NGI:	103746492(CUNH11orf70)

HGL:

101719843

CPOC:

100735385(CUNH11orf70)

CCAN:

109689095(CUNH11orf70)

DORD:

105980712

DSP:	122110396(Cfap300)

DMER:

138809899 138824462

PLOP:

125349688(Cfap300)

NCAR:

124959790

MMMA:

107146004(Cfap300)

ITI:	101959532(Cfap300)

OCU:	100342680(CFAP300)

OPI:	101529190(CFAP300)

OCZ:	121154259(CFAP300)

TUP:

102495286

GVR:

103586682

CFA:	611894(CFAP300)

CLUD:

112671453(CFAP300)

VVP:	112925933(CFAP300)

VLG:	121500779(CFAP300)

NPO:	129497019(CFAP300)

AML:	100476903(CFAP300)

UMR:	103662466(CFAP300)

UAH:	113260146(CFAP300)

UAR:	123792496(CFAP300)

ELK:

111153820

LLV:

125110229

MPUF:

101693055

MNP:	131998721(CFAP300)

MLK:	131834473(CFAP300)

NVS:	122912261(CFAP300)

ORO:

101372551

EJU:	114211416(CFAP300)

ZCA:	113914750(CFAP300)

MLX:	118013140(CFAP300)

NSU:	110586382(CFAP300)

LWW:	102746632(CFAP300)

FCA:	101083199(CFAP300)

PYU:	121020802(CFAP300)

PCOO:

112865902(CFAP300)

PBG:	122482881(CFAP300)

PVIV:

125175969(CFAP300)

LRUF:

124504795

LGF:	123602227(CFAP300)

AJU:	106976482(CFAP300)

PTG:

102952308

PPAD:

109257527(CUNH11orf70)

PUC:

125910854

PLEZ:

122199159(CFAP300)

HHV:	120219682(CFAP300)

BTA:	617430(CFAP300)

BOM:	102271038(CFAP300)

BIU:	109570013(C15H11orf70)

BBUB:

102391583(CFAP300)

BBIS:

104980166

CHX:	102175044(C15H11orf70)

OAS:	101121882(CFAP300)

BTAX:

128060914(CFAP300)

CSUM:

138093215(CFAP300)

ODA:	120876165(CFAP300)

CCAD:

122450362(CFAP300)

MREE:

136174954(CFAP300)

OVR:	110128542(CFAP300)

MBEZ:

129554253(CFAP300) 129560306

SSC:	100520444(C9H11orf70)

CFR:	102513265(CFAP300)

CBAI:

105083474

CDK:	105087180(CFAP300)

VPC:	102530726(CFAP300)

BACU:

103006339

BMUS:

118898792(CFAP300)

LVE:

103086419

OOR:	101275219(CFAP300)

LALB:

132525362(CFAP300)

GMF:	115867466(CFAP300)

DDP:	132429007(CFAP300)

DLE:	111168378(CFAP300)

PCAD:

102975284(CFAP300)

PSIU:

116758137(CFAP300)

PPHC:

136127334(CFAP300)

NASI:

112409968(CFAP300)

ECB:	100630215(C7H11orf70)

EPZ:	103552622(CFAP300)

EAI:	106845873(CFAP300)

MYB:

102240150

MYD:

102773199

MMYO:

118664476(CFAP300)

MLF:	102430332(CUNH11orf70)

MDT:	132240627(CFAP300)

MYUM:

139018262(CFAP300)

PKL:	118713285(CFAP300)

EFUS:

103292958(CFAP300)

MNA:

107532420

DRO:	112317557(CFAP300)

SHON:

118975685(CFAP300)

AJM:	119045155(CFAP300)

PDIC:

114499853(CFAP300)

PHAS:

123805502(CFAP300)

MMF:	118628778(CFAP300)

PPAM:

129085854(CFAP300)

HAI:	109375117(CUNH11orf70)

RFQ:	117030192(CFAP300)

PALE:

102883969(CFAP300)

PGIG:

120618089(CFAP300)

PVP:	105298274(CUNH11orf70)

RAY:	107504643(CFAP300)

MJV:	108409419(CFAP300)

TOD:	119240922(CFAP300)

SARA:

101553502

SFUM:

130024424(CFAP300)

SETR:

126015765(CFAP300)

LAV:	100658697(CUNH11orf70)

TMU:

101343635

ETF:	101660072(CFAP300)

DNM:	101424100(CUNH11orf70)

MDO:	100011960(C4H11orf70)

GAS:	123238985(CFAP300)

SHR:	100932604(CFAP300)

AFZ:

127554916

PCW:	110214952(CUNH11orf70)

TVP:	118839318(CFAP300)

PBRV:

138154995(CFAP300)

MLAO:

141508172(CFAP300)

OAA:	100079265(CFAP300)

TACU:

119941492(CFAP300)

GGA:	418985(C1H11ORF70)

MGP:	100545100(CFAP300)

CJO:	107308392(CFAP300)

TPAI:

128074820(CFAP300)

NMEL:

110389948(C1H11orf70)

APLA:

101797947(CFAP300)

ACYG:

106034196(CFAP300)

CATA:

118245891(CFAP300)

AFUL:

116501865(CFAP300)

TGU:	100231147(CFAP300)

LSR:	110470052(CFAP300)

SCAN:

103827280(CFAP300)

PMOA:

120506784(CFAP300)

OTC:	121342549(CFAP300)

PRUF:

121364243(CFAP300)

ATRC:

139593351(CFAP300)

GFR:

102031369

FAB:	101820581(C1H11orf70)

OMA:	130248467(CFAP300)

PHI:

102109756

PMAJ:

107213372(CFAP300)

CCAE:

111924371(CFAP300)

CCW:	104690069(CFAP300)

CBRC:

103617957(CUNH11orf70)

ACOE:

138110214(CFAP300)

ETL:	114070501(CFAP300)

ZAB:	102071100(CFAP300)

ZLE:	135458191(CFAP300)

ACHL:

103808991

SVG:

106859390

MMEA:

130576281(CFAP300)

HRT:	120748791(CFAP300)

SATI:

136374105(CFAP300)

CCIC:

134057514(CFAP300)

FPG:

101913300

FCH:	102051792(CFAP300)

CCRI:

104166807

NNT:

104400899

SHAB:

115604082(CFAP300)

ACUN:

113479501(CFAP300)

TALA:

104356205(CFAP300)

ACHC:

115353359(CFAP300)

HALD:

104311507

HLE:

104838457

AGEN:

126048370

HHAR:

128153549(CFAP300)

GCL:

CSTI:

LDI:

MNB:

DPUB:

PPUS:

135189893(CFAP300)

AVIT:

104272892

BRHI:

104488676

EGZ:	104128915(CFAP300)

NNI:

PCRI:

PCAO:

PADL:

AFOR:

103905943(CUNH11orf70)

FGA:

104078054

CBOR:

142077938(CFAP300)

GSTE:

104264283

CBOY:

140646551(CFAP300)

MAME:

142404357(CFAP300)

CLV:	102090711(CUNH11orf70)

CNIC:

135994604(CFAP300)

MUI:

PGUU:

PLET:

EHS:

CMAC:

CUCA:

104055052(CFAP300)

TEO:

104383414

BREG:

104638084

OHA:

104333057

ACAR:

104525295(CFAP300)

CPEA:

104390308

CVF:

104290317

RTD:	128904054(CFAP300)

CRID:

134513371(CFAP300)

LMIC:

141737962(CFAP300)

AAM:

106495506

AROW:

112971959(CFAP300)

NPD:	112943721(CFAP300)

TGT:

104564971

DNE:	112988758(CFAP300)

SCAM:

104143701

ASN:	102369237(CFAP300)

AMJ:	106737869(CUNH11orf70)

CPOO:

109305545(CUNH11orf70)

GGN:	109302210(CUNH11orf70)

CIZ:	142007948(CFAP300)

TST:	117871181(CFAP300)

CABI:

116814906(CFAP300)

MRV:	120368885(CFAP300)

ACS:	100561630(c3h11orf70)

ASAO:

132770079(CFAP300)

PVT:	110080253(CUNH11orf70)

SUND:

121927131(CFAP300)

PBI:	103056796(CFAP300)

PMUR:

107286353(CFAP300)

CTIG:

120297725(CFAP300)

TSR:

106555417

PGUT:

117660779(CFAP300)

PCAE:

139317060(CFAP300)

APRI:

131199654(CFAP300)

PTEX:

113440491(CFAP300)

NSS:	113417326(CFAP300)

VKO:	123029054(CFAP300)

PMUA:

114595656(CFAP300)

PRAF:

128412582(CFAP300)

ZVI:	118085349(CFAP300)

HCG:	128326433(CFAP300)

GJA:

107121581

STOW:

125431116(CFAP300)

EMC:	129325480(CFAP300)

XLA:	495953(cfap300.L)

XTR:	496912(cfap300)

NPR:	108800024(CUNH11orf70)

RTEM:

120929022(CFAP300)

ACAT:

141129777(CFAP300)

PADS:

140324805(CFAP300)

BBUF:

120996410(CFAP300)

BGAR:

122933133(CFAP300)

DTC:	141096381(CFAP300)

PWL:	138267952(CFAP300)

MUO:	115467864(CFAP300)

GSH:	117361906(CFAP300)

DRE:	497149(cfap300)

SRX:

107731447

SANH:

107681129

SGH:

107548131

CCAR:

109057852(cfap300)

CAUA:

113038607(cfap300)

CGIB:

127985788

PTET:

122326676(cfap300)

LROH:

127151927(cfap300)

GRF:	141293027(cfap300)

OMC:	131529455(cfap300)

PPRM:

120494662(cfap300)

RKG:	130096555(cfap300)

MAMB:

125253507(cfap300)

CIDE:

127503273

CERY:

137013144(cfap300)

MASI:

127430899

TROS:

130570425(cfap300)

TDW:	130407545(cfap300)

MANU:

129423947(cfap300)

PDAB:

135776300(cfap300)

IPU:	100528867(cfap300)

IFU:	128622208(cfap300)

PHYP:

113541701(cfap300)

SMEO:

124398317(cfap300)

TFD:	113634976(cfap300)

TVC:	132860143(cfap300)

CGAR:

128507753(cfap300)

NGRA:

132894962(cfap300)

TRN:	134330647(cfap300)

AMEX:

103038952(cfap300)

CMAO:

118820706(cfap300)

EEE:	113573443(cfap300)

CHAR:

105895380(cfap300)

SPIL:

134079920(cfap300)

ASAD:

121709305(cfap300)

TRU:	101067475(cfap300)

TFS:	130518239(cfap300)

TNG:	GSTEN00004715G001

LCO:	104922575(cfap300)

NCC:

104947160

TBEN:

117478272(cfap300)

CGOB:

115015827(cfap300)

PGEO:

117455528(cfap300)

GACU:

117563023(cfap300)

EMAC:

134875073(cfap300)

ELY:	117263888(cfap300)

EFO:	125904840(cfap300)

PLEP:

121957529(cfap300)

SLUC:

116067070(cfap300)

ECRA:

117957276(cfap300)

ESP:	116702055(cfap300)

PFLV:

114568548(cfap300)

GAT:	120826445(cfap300)

PPUG:

119219684(cfap300)

AFB:	129096751(cfap300)

CLUM:

117739378(cfap300)

PSWI:

130195272(cfap300)

CANA:

137784628(cfap300)

CVE:	137886231(cfap300)

MSAM:

119908139(cfap300)

SCHU:

122864657(cfap300)

CUD:	121524418(cfap300)

SPUL:

138609490(cfap300)

LMIX:

132991301(cfap300)

HTC:	141803302(cfap300)

ALAT:

119016895(cfap300)

ASTR:

137607707(cfap300)

MZE:	101474473(cfap300)

ONL:	100700636(cfap300)

OAU:	116312095(cfap300)

OLA:	101158461(cfap300)

OML:	112163184(cfap300)

CSAI:

133461087(cfap300)

XMA:	102219113(c13h11orf70)

XCO:	114156253(cfap300)

XHE:	116731917(cfap300)

PRET:

103472346(clg11h11orf70)

PFOR:

103135079

PLAI:

106954529

PMEI:

106927012

GAF:	122843649(cfap300)

PPRL:

129374985(cfap300)

CVG:

107083261

CTUL:

119785920(cfap300)

GMU:	124879419(cfap300)

NFU:	107394816(csgr19h11orf70)

KMR:	108239679(cfap300)

ALIM:

106515781

NWH:	119425431(cfap300)

AOCE:

111578389(cfap300)

EJA:	138214885(cfap300)

BFRE:

138619618(cfap300)

MCEP:

125020224(cfap300)

CSEM:

103394366(c18h11orf70)

POV:	109631699(cunh11orf70)

SSEN:

122786445(cfap300)

SSOE:

131447648(cfap300)

HHIP:

117770627(cfap300)

HSP:	118124845(cfap300)

PPLT:

128462026(cfap300)

SMAU:

118292464(cfap300)

LCF:	108897820(cfap300)

SDU:

111223527

SLAL:

111659392(cunh11orf70)

XGL:	120786696(cfap300)

HCQ:	109524078(cunh11orf70)

SSCV:

125985025(cfap300)

SBIA:

133510695(cfap300)

PEE:	133411921(cfap300)

PTAO:

133489031(cfap300)

BPEC:

110167349(cunh11orf70)

ENY:	140361397(cfap300)

MALB:

109963996(cunh11orf70)

BSPL:

114865490(cfap300)

SJO:	128373902(cfap300)

SSCO:

133995914(cfap300)

TTY:	137198157(cfap300)

GMH:	115535998(cfap300)

STRU:

115153795(cfap300)

OTW:	112237122(cfap300)

OMY:	110533248(cfap300)

OGO:	124015714(cfap300)

ONE:	115116009(cfap300)

OKI:	109872535(cfap300)

OKE:	118389735(cfap300)

OMM:	135551089(cfap300)

OCLA:

139419363

SNH:	120056724(cfap300)

SFON:

129867919(cfap300)

CCLU:

121559373(cfap300)

ELS:	105009860(cfap300)

OEP:	134039973(cfap300)

PKI:	111838005(cfap300)

AANG:

118235606(cfap300)

AROT:

135263756(cfap300)

CCOG:

133134007(cfap300)

LOC:	102694138(clg3h11orf70)

PSPA:

121302636(cfap300)

ARUT:

117405615 117973070(cfap300)

PSEX:

120523238(cfap300)

LCM:

102352721

CMK:	103177432(cfap300)

RTP:	109939039(cfap300)

CPLA:

122550414(cfap300)

CPUN:

140481682(cfap300)

HOC:	132816608(cfap300)

SCAU:

119977529(cfap300)

LERI:

129698290

HAKA:

140725952(cfap300)

PMRN:

116958070(CFAP300)

LRJ:	133361012(CFAP300)

BFO:

BBEL:

CIN:

SCLV:

SPU:	105437371 582091

LPIC:

129278540 129279392

LVG:	121429496 121429857

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:

PFLL:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

ACOC:

MZT:

CCOA:

TCZ:

TSEP:

VEM:

COBS:

TLN:

DQU:

CFO:

FEX:

PMEC:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

CTYP:

FAS:

DAM:

AGIF:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

API:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:	103519730 113472435

CLEC:

HHAL:

NLU:

LDA:

HVI:

MQU:	129000286 129001700

PHU:	Phum_PHUM076680

TPAL:

ZNE:

CSEC:

PAME:

SGRE:

BROR:

IEL:

HAMR:

PVM:

PJA:	122245018 122260229

PCHN:

PMOO:

HAME:

PCLA:

MRJ:

PORN:

PPOI:

CSCU:

CVS:

ABRU:

SDM:

HRO:	HELRODRAFT_156718

LGI:	LOTGIDRAFT_229887

PVUL:

PCAN:

LSAX:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

YBA:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

OVI:	T265_10341

LLON:

NVE:

EPA:

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:	124446511 124447317

HSY:

130621614

RES:

135684443

AQU:

100639115

CRE:	CHLRE_12g556300v5

VCN:	VOLCADRAFT_120268

MIS:	MICPUN_57695

MPP:	MICPUCDRAFT_52185

RIE:	OCT59_012583

TET:	TTHERM_00586530

PTM:	GSPATT00011350001

PIF:	PITG_06904

PSOJ:

PHYSODRAFT_481394

SPAR:

SPRG_04459

SSAO:

94296593(SS50377_22570)

EHX:	EMIHUDRAFT_206666

GTT:	GUITHDRAFT_163320

» show all

Reference

PMID:29727693

Authors

Hoben IM, Hjeij R, Olbrich H, Dougherty GW, Nothe-Menchen T, Aprea I, Frank D, Pennekamp P, Dworniczak B, Wallmeier J, Raidt J, Nielsen KG, Philipsen MC, Santamaria F, Venditto L, Amirav I, Mussaffi H, Prenzel F, Wu K, Bakey Z, Schmidts M, Loges NT, Omran H

Title

Mutations in C11orf70 Cause Primary Ciliary Dyskinesia with Randomization of Left/Right Body Asymmetry Due to Defects of Outer and Inner Dynein Arms.

Journal

Am J Hum Genet 102:973-984 (2018)
DOI:10.1016/j.ajhg.2018.03.025

Sequence

[hsa:85016]

LinkDB

DBGET integrated database retrieval system