KEGG   ORTHOLOGY: K24252
Entry
K24252                      KO                                     
Symbol
wbvR, qnlA
Name
UDP-6-deoxy-4-keto-L-IdoNAc 3-epimerase / UDP-4-keto-L-RhaNAc 4-reductase [EC:1.1.1.-]
Pathway
map00541  O-Antigen nucleotide sugar biosynthesis
map01100  Metabolic pathways
map01250  Biosynthesis of nucleotide sugars
Reaction
R12553  
R12604  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00541 O-Antigen nucleotide sugar biosynthesis
    K24252  wbvR, qnlA; UDP-6-deoxy-4-keto-L-IdoNAc 3-epimerase / UDP-4-keto-L-RhaNAc 4-reductase
Other DBs
COG: COG1091
Genes
VTI: CEQ48_17735
ALKM: NKI27_13695
ENG: O2T12_14805
PAQT: E8L99_18525
AQK: AKACHI_08770
LEPT: JVX88_05120
MEND: L6E24_12870
MEFW: F1737_01180
MESB: L1S32_02375
AG: AAM22596(wbvR) AAR24275(qnlA)
Reference
PMID:12575896
  Authors
Kneidinger B, Larocque S, Brisson JR, Cadotte N, Lam JS
  Title
Biosynthesis of 2-acetamido-2,6-dideoxy-L-hexoses in bacteria follows a pattern distinct from those of the pathways of 6-deoxy-L-hexoses.
  Journal
Biochem J 371:989-95 (2003)
DOI:10.1042/BJ20030099
  Sequence
[ag:AAM22596]
Reference
PMID:14702307
  Authors
Feng L, Senchenkova SN, Yang J, Shashkov AS, Tao J, Guo H, Zhao G, Knirel YA, Reeves P, Wang L
  Title
Structural and genetic characterization of the Shigella boydii type 13 O antigen.
  Journal
J Bacteriol 186:383-92 (2004)
DOI:10.1128/jb.186.2.383-392.2004
  Sequence
[ag:AAR24275]
LinkDB

KEGG   REACTION: R12604
Entry
R12604                      Reaction                               
Definition
UDP-2-acetamido-2,6-dideoxy-beta-L-lyxo-4-hexulose + NADPH + H+ <=> UDP-2-acetamido-2,6-dideoxy-beta-L-mannose + NADP+
Equation
C20769 + C00005 + C00080 <=> C22259 + C00006
Comment
UDP-4-keto-L-RhaNAc 4-reductase
Reaction class
RC00182  C20769_C22259
Enzyme
1.1.1.-
Pathway
rn00541  O-Antigen nucleotide sugar biosynthesis
rn01100  Metabolic pathways
rn01250  Biosynthesis of nucleotide sugars
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.-
     R12604  UDP-2-acetamido-2,6-dideoxy-beta-L-lyxo-4-hexulose + NADPH + H+ <=> UDP-2-acetamido-2,6-dideoxy-beta-L-mannose + NADP+
Orthology
K24252  UDP-6-deoxy-4-keto-L-IdoNAc 3-epimerase / UDP-4-keto-L-RhaNAc 4-reductase [EC:1.1.1.-]
LinkDB

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