| Entry |
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| Symbol |
mycCI, CYP105L2
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| Name |
mycinamicin VIII C21 methyl hydroxylase [EC:1.14.-.-]
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| Pathway |
| map00522 | Biosynthesis of 12-, 14- and 16-membered macrolides |
| map01110 | Biosynthesis of secondary metabolites |
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| Module |
| M00934 | Mycinamicin biosynthesis, malonyl-CoA + methylmalonyl-CoA => protomycinolide IV => mycinamicin II |
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| Reaction |
| R10875 | mycinamicin-VIII,NADPH:oxygen oxidoreductase (21-hydroxylating) |
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| Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00522 Biosynthesis of 12-, 14- and 16-membered macrolides
K24292 mycCI, CYP105L2; mycinamicin VIII C21 methyl hydroxylase
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins
K24292 mycCI, CYP105L2; mycinamicin VIII C21 methyl hydroxylase
00199 Cytochrome P450
K24292 mycCI, CYP105L2; mycinamicin VIII C21 methyl hydroxylase
Polyketide biosynthesis proteins [BR:ko01008]
Polyketide tailoring proteins
Oxygenase
K24292 mycCI, CYP105L2; mycinamicin VIII C21 methyl hydroxylase
Cytochrome P450 [BR:ko00199]
Cytochrome P450, bacteria type
CYP105 family
K24292 mycCI, CYP105L2; mycinamicin VIII C21 methyl hydroxylase
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| Other DBs |
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| Genes |
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| Reference |
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| Authors |
Anzai Y, Saito N, Tanaka M, Kinoshita K, Koyama Y, Kato F |
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| Title |
Organization of the biosynthetic gene cluster for the polyketide macrolide mycinamicin in Micromonospora griseorubida. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
DeMars MD 2nd, Sheng F, Park SR, Lowell AN, Podust LM, Sherman DH |
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| Title |
Biochemical and Structural Characterization of MycCI, a Versatile P450 Biocatalyst from the Mycinamicin Biosynthetic Pathway. |
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| Journal |
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| LinkDB |
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