KEGG   ORTHOLOGY: K24306
Entry
K24306                      KO                                     
Symbol
lea4
Name
2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-D-mannopyranose transferase
Pathway
map00541  O-Antigen nucleotide sugar biosynthesis
map01100  Metabolic pathways
map01250  Biosynthesis of nucleotide sugars
Reaction
R12567  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00541 O-Antigen nucleotide sugar biosynthesis
    K24306  lea4; 2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-D-mannopyranose transferase
Other DBs
COG: COG2089
Genes
VVU: VV1_0808
VVM: VVMO6_02804
VHA: VIBHAR_00670
VCA: M892_09500
SEUR: FM038_016020(neuB)
SMAY: K0H60_06705(neuB)
RCL: NYR17_09615(neuB)
HAHS: HSRCO_1836(spsE)
HLS: KU306_12680(neuB)
LOB: NEF87_004337
AG: ADJ19196(lea4)
 » show all
Reference
PMID:20510395
  Authors
Li X, Perepelov AV, Wang Q, Senchenkova SN, Liu B, Shevelev SD, Guo X, Shashkov AS, Chen W, Wang L, Knirel YA
  Title
Structural and genetic characterization of the O-antigen of Escherichia coli O161 containing a derivative of a higher acidic diamino sugar, legionaminic acid.
  Journal
Carbohydr Res 345:1581-7 (2010)
DOI:10.1016/j.carres.2010.04.008
  Sequence
[ag:ADJ19196]
Reference
PMID:30315110
  Authors
McDonald ND, DeMeester KE, Lewis AL, Grimes CL, Boyd EF
  Title
Structural and functional characterization of a modified legionaminic acid involved in glycosylation of a bacterial lipopolysaccharide.
  Journal
J Biol Chem 293:19113-19126 (2018)
DOI:10.1074/jbc.RA118.004966
LinkDB

KEGG   REACTION: R12567
Entry
R12567                      Reaction                               
Definition
2-Acetamido-4-(D-alanylamino)-2,4,6-trideoxy-D-mannopyranose + Phosphoenolpyruvate + H2O <=> 5-N-Acetyl-7-N-(D-alanyl)-legionaminic acid + Orthophosphate
Equation
C22249 + C00074 + C00001 <=> C22250 + C00009
Comment
transferase
Reaction class
RC00159  C22249_C22250
Enzyme
2.5.1.-
Pathway
rn00541  O-Antigen nucleotide sugar biosynthesis
rn01100  Metabolic pathways
rn01250  Biosynthesis of nucleotide sugars
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.-
     R12567  2-Acetamido-4-(D-alanylamino)-2,4,6-trideoxy-D-mannopyranose + Phosphoenolpyruvate + H2O <=> 5-N-Acetyl-7-N-(D-alanyl)-legionaminic acid + Orthophosphate
Orthology
K24306  2-acetamido-4-(D-alanylamino)-2,4,6-trideoxy-D-mannopyranose transferase
LinkDB

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