KEGG ORTHOLOGY: K24471

ORTHOLOGY: K24471

Entry

K24471                      KO

Symbol

EPGN

Name

epigen

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified
    K24471  EPGN; epigen
Domain-containing proteins not elsewhere classified [BR:ko04990]
EGF-like domain-containing proteins
  Other EGF-like domain-containing proteins
   K24471  EPGN; epigen

Genes

HSA:	255324(EPGN)

PTR:	461252(EPGN)

PPS:	100974218(EPGN)

GGO:	101134672(EPGN)

PON:	100441894(EPGN)

PPYG:

129034993(EPGN)

NLE:	100589386(EPGN)

HMH:	116466925(EPGN)

SSYN:

129491723(EPGN)

MCC:	702632(EPGN)

MCF:	102121903(EPGN)

MTHB:

126954912

MNI:	105477286(EPGN)

CSAB:

103235803(EPGN)

CATY:

105576874(EPGN)

PANU:

101022080(EPGN)

TGE:	112625210(EPGN)

MLEU:

105529094(EPGN)

RRO:	104673175(EPGN)

RBB:	108515814(EPGN)

TFN:	117085483(EPGN)

PTEH:

111524572(EPGN)

CANG:

105501300(EPGN)

CJC:	100388654(EPGN)

SBQ:	101051199(EPGN)

CIMI:

108292193(EPGN)

ANAN:

105725367(EPGN)

CSYR:

103258899(EPGN)

MMUR:

105860473(EPGN)

LCAT:

123624718(EPGN)

PCOQ:

105822824(EPGN)

OGA:	100950207(EPGN)

MMU:	71920(Epgn)

MCAL:

110295382(Epgn)

MPAH:

110330944(Epgn)

RNO:	289515(Epgn)

MCOC:

116070646(Epgn)

ANU:	117712821(Epgn)

ASYL:

127696571(Epgn)

MUN:	110565264(Epgn)

CGE:	100771437(Epgn)

MAUA:

110340542(Epgn)

PROB:

127232101(Epgn)

PLEU:

114701720(Epgn)

MORG:

121460968(Epgn)

MFOT:

126506501

AAMP:

119815114(Epgn)

NGI:	103742433(Epgn)

HGL:	101704232(Epgn)

CPOC:

100715482(Epgn)

CCAN:

109681116(Epgn)

DORD:

105988535(Epgn)

DSP:	122106888(Epgn)

PLOP:

125364999(Epgn)

NCAR:

124994754

MMMA:

107153600(Epgn)

ITI:	101963062(Epgn)

OCU:

100343916

OPI:

101521270

TUP:	102474169(EPGN)

GVR:	103590265(EPGN)

CFA:	611937(EPGN)

CLUD:

112652349(EPGN)

VVP:	112909239(EPGN)

VLG:	121473798(EPGN)

NPO:	129519717(EPGN)

AML:	100464238(EPGN)

UMR:	103665315(EPGN)

UAH:	113263272(EPGN)

UAR:	123789158(EPGN)

ELK:

111149273

LLV:

125094406

MPUF:

101674187(EPGN)

MNP:	132015993(EPGN)

MLK:	131823132(EPGN)

NVS:	122889561(EPGN)

ORO:	101366250(EPGN)

EJU:	114206857(EPGN)

ZCA:	113925172(EPGN)

MLX:	118010206(EPGN)

NSU:	110591459(EPGN)

LWW:	102740155(EPGN)

FCA:	101081293(EPGN)

PYU:	121034373(EPGN)

PCOO:

112858463(EPGN)

PBG:	122478794(EPGN)

PVIV:

125164367(EPGN)

LRUF:

124521303

LGF:	123595853(EPGN)

AJU:

106982125

PTG:	102967513(EPGN)

PPAD:

109277688(EPGN)

PUC:

125922828

PLEZ:

122217109(EPGN)

HHV:	120231100(EPGN)

BTA:	100295331(EPGN)

BOM:	102269808(EPGN)

BIU:	109560582(EPGN)

BBUB:

102416546(EPGN)

BBIS:

104987309(EPGN)

CHX:	108633176(EPGN)

OAS:	101105158(EPGN)

BTAX:

128049915(EPGN)

CSUM:

138082190(EPGN)

ODA:	120861443(EPGN)

CCAD:

122428281(EPGN)

MREE:

136152984(EPGN)

OVR:	110131891(EPGN)

MBEZ:

129561744(EPGN)

SSC:	102161388(EPGN)

CFR:	102507461(EPGN)

CBAI:

105080378(EPGN)

CDK:	105091403(EPGN)

VPC:	102534122(EPGN)

BACU:

103004226(EPGN)

BMUS:

118895518(EPGN)

LVE:	103069479(EPGN)

OOR:	101272292(EPGN)

LALB:

132519290(EPGN)

DLE:	111187628(EPGN)

PCAD:

102992926(EPGN)

PSIU:

116754553(EPGN)

NASI:

112405663(EPGN)

ECB:	100050376(EPGN)

EPZ:	103565140(EPGN)

EAI:	106846381(EPGN)

MYB:	102245843(EPGN)

MYD:	102756271(EPGN)

MMYO:

118669849(EPGN)

MLF:	102440404(EPGN)

MDT:	132217998(EPGN)

MYUM:

138994813(EPGN)

PKL:	118705316(EPGN)

EFUS:

103288016(EPGN)

MNA:	107534496(EPGN)

DRO:	112319880(EPGN)

SHON:

118979461(EPGN)

AJM:	119052788(EPGN)

PDIC:

114493226(EPGN)

PHAS:

123831168(EPGN)

MMF:	118641446(EPGN)

PPAM:

129085256(EPGN)

HAI:	109371838(EPGN)

RFQ:	117022392(EPGN)

PALE:

102884984(EPGN)

PGIG:

120588206(EPGN)

PVP:	105292344(EPGN)

RAY:	107515313(EPGN)

MJV:	108397672(EPGN)

TOD:	119260680(EPGN)

SARA:

101559175(EPGN)

SFUM:

130020667(EPGN)

SETR:

126032181(EPGN)

LAV:	100664842(EPGN)

TMU:

101356744

ETF:	101638678(EPGN)

DNM:	101443852(EPGN)

MDO:	100023880(EPGN)

GAS:	123252013(EPGN)

SHR:	100933856(EPGN)

AFZ:

127539994

PCW:	110209786(EPGN)

TVP:	118855354(EPGN)

PBRV:

138164172(EPGN)

OAA:	114814673(EPGN)

TACU:

119939674(EPGN)

GGA:	497270(EPGN)

MGP:	100538470(EPGN)

CJO:	107313339(EPGN)

TPAI:

128080198(EPGN)

LMUT:

125691950(EPGN)

NMEL:

110397999(EPGN)

ACYG:

106041917(EPGN)

AFUL:

116488817(EPGN)

FAB:	107603587(EPGN)

PHI:	102107507(EPGN)

ACOE:

138109250(EPGN)

ZAB:	102061521(EPGN)

ZLE:	135446926(EPGN)

ACHL:

103800025(EPGN)

MMEA:

130582866(EPGN)

HRT:	131378559(EPGN)

SATI:

136360737(EPGN)

CCIC:

134044121(EPGN)

FCH:	114014814(EPGN)

CCRI:

104165984(EPGN)

NNT:	104406439(EPGN)

HALD:

104317827(EPGN)

HLE:	104836755(EPGN)

AGEN:

126044747

HHAR:

128152990(EPGN)

GCL:

127015801

CSTI:

104555930(EPGN)

LDI:	104354132(EPGN)

MNB:	103781303(EPGN)

DPUB:

104297136(EPGN)

PPUS:

135178639(EPGN)

AVIT:

104279178(EPGN)

BRHI:

104493664(EPGN)

NNI:	104015864(EPGN)

PCRI:

104031753(EPGN)

PCAO:

104045806(EPGN)

PADL:

103917700(EPGN)

AFOR:

103898932(EPGN)

FGA:	104078158(EPGN)

GSTE:

104264836(EPGN)

MUI:	104547917(EPGN)

PGUU:

104468148(EPGN)

PLET:

104617754(EPGN)

EHS:	104513799(EPGN)

CMAC:

104486157(EPGN)

TEO:	104375961(EPGN)

BREG:

104629017(EPGN)

OHA:	104331887(EPGN)

ACAR:

104532490(EPGN)

CPEA:

104394079(EPGN)

CVF:	104288013(EPGN)

AROW:

112977625(EPGN)

TGT:	104565062(EPGN)

SCAM:

104149938(EPGN)

ASN:	102374213(EPGN)

AMJ:	102575330(EPGN)

CPOO:

109309511(EPGN)

GGN:	109297130(EPGN)

PSS:	102453513(EPGN)

CMY:	102947458(EPGN)

CCAY:

125635403(EPGN)

DCC:	119854966(EPGN)

CPIC:

101935496(EPGN)

TST:	117878093(EPGN)

CABI:

116814585(EPGN)

MRV:	120407055(EPGN)

ASAO:

132779635(EPGN)

PVT:	110090463(EPGN)

PMUA:

114582605(EPGN)

PRAF:

128399943(EPGN)

ZVI:	118094571(EPGN)

HCG:	128331332(EPGN)

XLA:	108706767(epgn.S)

XTR:	100216288(epgn)

MUO:	115462500(EPGN)

GSH:	117358737(EPGN)

DRE:	100005297(epgn)

SRX:	107711904 107738999

SANH:

107667561(epgn)

SGH:	107565989 107599986

CCAR:

109071085 109075216

CAUA:

113096345 113107274 113107724

CGIB:

127963114 128018497

PTET:

122350935(epgn)

LROH:

127169262(epgn)

PPRM:

120485226(epgn)

RKG:	130072425(epgn)

MAMB:

125280661(epgn)

CIDE:

127517438

CERY:

137026383(epgn)

MASI:

127415334 127424391

TROS:

130567991(epgn)

TDW:	130407243(epgn)

MANU:

129414251(epgn)

PDAB:

135729548(epgn) 135757575

IPU:

108265590

PHYP:

113525509(epgn)

SMEO:

124400245(epgn)

TFD:	113650388(epgn)

TVC:	132853597(epgn)

CGAR:

128529802

NGRA:

132892373(epgn)

AMEX:

103041751(epgn)

CMAO:

118813032(epgn)

CHAR:

SPIL:

TRU:

TFS:

LCO:

NCC:	104962118(epgn)

TBEN:

117472877(epgn)

CGOB:

115014111(epgn)

PGEO:

117452437(epgn)

GACU:

117559840(epgn)

EMAC:

134874167(epgn)

ELY:	117252091(epgn)

EFO:	125890419(epgn)

PLEP:

121944616(epgn)

SLUC:

116054288

ECRA:

117945332(epgn)

ESP:

116688847

PFLV:

114556218(epgn)

GAT:

120830312

PPUG:

119225602(epgn)

AFB:

129101866

CLUM:

117736394(epgn)

PSWI:

130197284(epgn)

CANA:

137779191(epgn)

CVE:

137867416

MSAM:

119891215 119898534

SCHU:

122876954(epgn)

CUD:	121510419(epgn)

SPUL:

138610530

LMIX:

132974993

ALAT:

119020101(epgn)

ASTR:

137592433

MZE:

101482002

ONL:

100693895

OAU:	116310980(epgn)

OLA:

OML:

CSAI:

XMA:

XCO:

XHE:

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122828038(epgn)

PPRL:

129365882(epgn)

CVG:

107085304

CTUL:

119778182(epgn)

GMU:	124878419(epgn)

NFU:

107394300

KMR:

108233673

ALIM:

106519868

NWH:	119413876(epgn)

AOCE:

111580755(epgn)

EJA:	138191739(epgn)

BFRE:

138626320(epgn)

MCEP:

CSEM:

POV:

SSEN:

SSOE:

HHIP:

117768441(epgn)

HSP:	118115300(epgn)

PPLT:

128438959(epgn)

SMAU:

118314640(epgn)

LCF:	108881401(epgn)

SLAL:

111654899(epgn)

XGL:	120805664(epgn)

SBIA:

133498852

PEE:	133400001(epgn)

PTAO:

133475098(epgn)

BPEC:

110175274

MALB:

109956495

BSPL:

114863051(epgn)

SJO:

128364174

SSCO:

133979725

GMH:

115554251

SASA:

100196116(epgn) 106585940(EPGN)

STRU:

115165035 115200613

OTW:	112246153 121847911

OMY:	110525168 118937416

OGO:	124034714 124035322

ONE:	115117168 115120686

OKI:	109884926 109895182

OKE:	127911822 127911823 127911824

OMM:	135509925 135513720

OCLA:

139389898 139410562 139411871

SALP:

112070981

SNH:	120050050 120062971

CCLU:

121584026 121587275

ELS:	105008248(epgn)

OEP:	134012002(epgn)

SFM:	108938601(epgn)

PKI:	111855438(epgn)

AANG:

118237322

AROT:

135233504

CCOG:

133141036(epgn)

LOC:	102685433(epgn)

PSPA:

121298614 121319712

ARUT:

117408353 117420600

LCM:	102354282(EPGN)

CMK:

CPLA:

HOC:

LERI:

PMRN:

LRJ:

BBEL:

CRG:

Reference

PMID:15611079

Authors

Kochupurakkal BS, Harari D, Di-Segni A, Maik-Rachline G, Lyass L, Gur G, Kerber G, Citri A, Lavi S, Eilam R, Chalifa-Caspi V, Eshhar Z, Pikarsky E, Pinkas-Kramarski R, Bacus SS, Yarden Y

Title

Epigen, the last ligand of ErbB receptors, reveals intricate relationships between affinity and mitogenicity.

Journal

J Biol Chem 280:8503-12 (2005)
DOI:10.1074/jbc.M413919200

Sequence

[hsa:255324]

LinkDB

DBGET integrated database retrieval system