KEGG ORTHOLOGY: K24696

ORTHOLOGY: K24696

Entry

K24696                      KO

Symbol

mftC

Name

[mycofactocin precursor peptide]-tyrosine decarboxylase / 3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one synthase [EC:1.3.98.7 4.1.99.26]

Brite

KEGG Orthology (KO) [BR:ko00001]
09190 Not Included in Pathway or Brite
  09191 Unclassified: metabolism
   99980 Enzymes with EC numbers
    K24696  mftC; [mycofactocin precursor peptide]-tyrosine decarboxylase / 3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one synthase
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.98  With other, known, physiological acceptors
    1.3.98.7  [mycofactocin precursor peptide]-tyrosine decarboxylase
     K24696  mftC; [mycofactocin precursor peptide]-tyrosine decarboxylase / 3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one synthase
4. Lyases
  4.1  Carbon-carbon lyases
   4.1.99  Other carbon-carbon lyases
    4.1.99.26  3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one synthase
     K24696  mftC; [mycofactocin precursor peptide]-tyrosine decarboxylase / 3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one synthase

Other DBs

COG:

COG0535

Genes

PVB:	J5X90_01710

BURK:

DM992_04425

URU:	DSM104443_01508(mftC)

UPL:	DSM104440_02432(moaA_2) DSM104440_02434(mftC)

WEE:	LOK48_06000

SPAP:

H3Z74_12905

DEX:	HWD60_01690(mftC)

DVN:	HQ394_08780(mftC)

GPI:	GPICK_06635

GEB:

GM18_3219

GUR:

Gura_3559

GHC:	L9S41_14665(mftC)

DLI:	dnl_37460(mftC)

AORY:

AMOR_45640(mftC)

MYX:	QEG98_18495

PSON:

PMAE:

PTH:

DAE:

ACHT:

MTU:

MTV:

MTC:

MRA:	MRA_0701(pqqE)

MTF:	TBFG_10707

MTB:	TBMG_00706

MTK:	TBSG_00710

MTZ:	TBXG_000699

MTI:	MRGA423_04325

MTE:	CCDC5079_0644

MTUR:

CFBS_0729(pqqE)

MTL:	CCDC5180_0635

MTO:	MTCTRI2_0709(pqqE)

MTD:	UDA_0693(pqqE)

MTN:	ERDMAN_0765(pqqE)

MTJ:	J112_03710

MTUB:

MT7199_0711

MTUE:

J114_03700

MTX:	M943_03605

MTUL:

TBHG_00688

MTUT:

HKBT1_0729(pqqE)

MTUU:

HKBT2_0730(pqqE)

MTQ:	HKBS1_0729(pqqE)

MBO:	BQ2027_MB0712(pqqE)

MBB:	BCG_0742(pqqE)

MBT:	JTY_0712(pqqE)

MBM:	BCGMEX_0713(pqqE)

MBK:	K60_007390

MBX:

BCGT_0485

MAF:	MAF_07020(pqqE)

MMIC:

RN08_0773

MCE:	MCAN_06941(pqqE)

MCQ:	BN44_10763(pqqE)

MCV:	BN43_20125(pqqE)

MCX:	BN42_20448(pqqE)

MCZ:	BN45_10793(pqqE)

MORY:

MO_000738(mftC)

MPA:	MAP_4153(pqqE)

MAO:

MAVI:

MAVU:

MAV:

MIT:

MIA:

MID:

MYO:

MCHI:

MIR:

MMAL:

CKJ54_20795(mftC)

MLP:

MLM_3634

MMAN:

MMAN_31920(mftC)

MSA:	Mycsm_00993

MUL:	MUL_0773(pqqE)

MMI:	MMAR_1021(pqqE)

MMAE:

MMARE11_09740(pqqE)

MLI:	MULP_01148(pqqE)

MPSE:

MPSD_11580(pqqE)

MSHO:

MSHO_28100(mftC)

MMC:

MKM:

MJL:

MMM:

MKN:	MKAN_19590

MYV:	G155_07135

MYE:	AB431_05550

MHAD:

B586_18795

MDX:	BTO20_28590

MSHG:

MSG_00882(mftC)

MFJ:	MFLOJ_25800(mftC)

MSTO:

MSTO_29440(mftC)

MSIM:

MSIM_16080(mftC)

MSAK:

MSAS_44570(pqqE)

MKU:	I2456_05200(mftC)

MLW:	MJO58_04700(mftC)

MXE:	MYXE_39990

MNV:	MNVI_25240

MPAG:

C0J29_05580(mftC)

MNM:	MNVM_27250

MGOR:

H0P51_05075(mftC)

MCOO:

MCOO_41760

MBAI:

MB901379_00882(albA)

MSEO:

MSEO_48250(pqqE)

MHEK:

JMUB5695_03904

MGAU:

MGALJ_54730

MLJ:	MLAC_34950(pqqE)

MBRD:

MBRA_06490(mftC)

MSHJ:

MSHI_27520(mftC)

MMAM:

K3U93_04265(mftC)

MSPG:

F6B93_04315(mftC)

MOT:	LTS72_20560(mftC)

MPAA:

MKK62_01650(mftC) MKK62_20125(mftC)

MMEH:

M5I08_04070(mftC) M5I08_21200(mftC)

MKY:	IWGMT90018_10150(pqqE)

MADI:

A7U43_25310

MWU:	PT015_22325(mftC)

MSM:	MSMEG_1423

MSG:	MSMEI_1388(pqqE)

MSB:	LJ00_07095

MSN:	LI99_07095

MSH:	LI98_07095

MVA:

Mvan_1296

MGI:

Mflv_5060

MSP:	Mspyr1_44780

MCB:	Mycch_0934

MNE:	D174_06605

MYN:	MyAD_06470

MFT:	XA26_14270

MPHL:

MPHLCCUG_01293(albA)

MVQ:

MYVA_1101

MLL:	B1R94_05275

MRH:	MycrhN_0708

MTHN:

4412656_00903(moaA_1)

MHAS:

MHAS_00222(mftC)

MDU:	MDUV_34210

MCHT:

MCHIJ_01200

MDR:	MDOR_06280

MAUU:

NCTC10437_01079(moaA_1)

MMAG:

MMAD_11150

MMOR:

MMOR_54180

MFX:	MFAL_21360

MAIC:

MAIC_45870

MIJ:	MINS_13330

MALV:

MALV_24330

MTY:	MTOK_31920

MPSC:

MARZ:

MGAD:

MHEV:

MSAR:

MANY:

MAUB:

MPOF:

MPHU:

MMUC:

C1S78_023005(mftC)

MMAT:

MMAGJ_31370 MMAGJ_42610

MBOK:

MBOE_62330

MFG:	K6L26_25505(mftC)

MSEI:

MSEDJ_23770

MFLV:

NCTC10271_04120(moaA_2)

MCEE:

MCEL_23190

MMON:

EWR22_05390(mftC)

MGO:	AFA91_31800

MHOL:

K3U96_21205(mftC)

MSEN:

K3U95_06215(mftC)

MPAE:

K0O64_05085(mftC)

MRF:	MJO55_05335(mftC)

MDF:	K0O62_05970(mftC)

MCRO:

MI149_05810(mftC)

MGRO:

FZ046_11350(mftC)

MKR:	MKOR_22780

MPAK:

MIU77_15075(mftC)

MAB:

MAB_3835c

MMV:	MYCMA_2121

MABB:

MASS_3846

MABL:

MMASJCM_3850

MCHE:

BB28_19635

MIZ:	BAB75_21910

MSTE:

MSTE_03984

MSAO:

MYCSP_17705

MSAL:

DSM43276_03628(albA_1)

MJD:	JDM601_3348(pqqE)

MTER:

4434518_03335(pqqE)

MMIN:

MMIN_10500

MHIB:

MHIB_27760

MHER:

K3U94_19120(mftC)

MVM:	MJO54_19085(mftC)

ASD:	AS9A_4328 AS9A_4370

NFA:	NFA_22330 NFA_34430

NFR:	ERS450000_00607(moaA_1) ERS450000_01864(moaA_2)

NCY:	NOCYR_4848

NBR:	O3I_038110

NNO:	NONO_c43730

NSL:	BOX37_28985

NOZ:	DMB37_16920

NAH:	F5544_40635(mftC)

NAD:	NCTC11293_06440(moaA_2)

NWL:	NWFMUON74_31340

NIE:	KV110_01685 KV110_37300(mftC)

NGP:	LTT66_16810(mftC) LTT66_27865

NSPU:

IFM12276_04450

RHA:	RHA1_ro06072

RER:

RER_17990

REY:

O5Y_08630

REB:	XU06_08870

RQI:	C1M55_09105(mftC)

ROP:

ROP_61300

ROA:	Pd630_LPD02713

RPY:	Y013_08775

RBY:	CEJ39_19670(mftC)

RHB:

NY08_1952

RAV:	AAT18_18590

RFA:	A3L23_00297(mftC)

RHS:	A3Q41_03117(mftC)

RHW:	BFN03_03195

RRZ:	CS378_08060(mftC)

RHU:	A3Q40_00412(mftC)

RHQ:	IM25_00605

RHOD:

AOT96_19470

RRT:	4535765_03565(moaA_2)

RCR:	NCTC10994_03687(moaA_1)

RTM:	G4H71_16285(mftC)

RKO:	JWS14_33110(mftC)

RGO:	KYT97_09560(mftC)

ROZ:	CBI38_20395

RPSK:

JWS13_10850(mftC)

RANT:

RHODO2019_14325(mftC)

RHOP:

D8W71_12595(mftC)

REQ:

REQ_36270

PDEF:

P9209_16155(mftC)

WHR:	OG579_07510(mftC)

GBR:

Gbro_3778

GPO:	GPOL_c36480

GOR:

KTR9_3737

GOQ:	ACH46_15915

GTA:	BCM27_19570

GOC:	CXX93_06955(mftC)

GIT:	C6V83_16215(mftC)

GRU:	GCWB2_19180(albA)

GOM:	D7316_04926(mftC)

GAV:	C5O27_08960(mftC)

GOD:	GKZ92_18110(mftC)

GAM:	GII34_18050(mftC)

GPD:	GII33_17505(mftC)

GJI:	H1R19_17930(mftC)

GOI:	LK459_15805(mftC)

GHN:	MVF96_18495(mftC)

GAMI:

IHQ52_22085(mftC)

GMG:	NWF22_03545(mftC)

GSI:	P5P27_15285(mftC)

SPIN:

KV203_02225(mftC)

TSM:	ASU32_04090

TSD:	MTP03_02840

DTM:	BJL86_2336

DIT:	C3V38_01380(mftC)

DIZ:	CT688_11595(mftC)

DPC:	A6048_12175

DLU:	A6035_11195

DKN:	NHB83_11615(mftC)

TOY:	FO059_05810(mftC)

SHY:

SHJG_2443

SHO:	SHJGH_2208

SBRO:

GQF42_07985(mftC)

STUI:

GCM10017668_53920

SPRA:

CP972_11025(mftC)

SYAN:

NRK68_35035(mftC)

SCIR:

STRCI_007929(mftC)

SANT:

QR300_11390(mftC)

YIA:	LO772_03300(mftC)

MSED:

E3O41_00690(mftC)

MSF:	IT882_01150(mftC)

MCAW:

F6J84_03070(mftC)

MELY:

L2X98_31250(mftC)

FRP:	AX769_01345

FSB:	GCM10025867_43650

AMAV:

GCM10025877_11620

CPHY:

B5808_07270

CHRE:

IE160_03000(mftC)

HUM:	DVJ78_13615(mftC)

LALL:

MUN78_02670(mftC)

HEA:	HL652_05825(mftC)

SUBA:

LQ955_14985(mftC)

AJG:	KKR91_08595(mftC)

AZX:	N2K95_07805(mftC)

AJR:	N2K98_08415(mftC)

ALX:	LVQ62_05585(mftC)

BEI:	GCM100_01140

JLI:	EXU32_11045(mftC)

JAY:	H7A72_14560(mftC)

PHW:	G7075_01305(mftC)

NDP:	E2C04_03200(mftC)

NARO:

CFH99_21865(mftC) CFH99_24470(mftC)

NAQU:

ENKNEFLB_00509(mftC)

NRO:	K8W59_04795(mftC)

NPC:	KUV85_09740(mftC)

NPS:	KRR39_16395(mftC)

NMAR:

HPC71_02600(mftC)

PSIM:

KR76_24775

AEZ:	C3E78_15430(mftC)

AEB:	C6I20_03055(mftC)

AEF:	GEV26_02910(mftC)

NBT:	KLP28_13005(mftC)

NGV:	CDO52_16170(mftC)

SAIU:

J4H86_09360(mftC)

TCU:

Tcur_2362

ACTW:

F7P10_02075(mftC)

AMAZ:

LUW76_43950(mftC)

FRE:	Franean1_3326

FAL:	FRAAL3572(pqqE)

FSY:	FsymDg_2656

FRI:	FraEuI1c_0997

NML:

Namu_0775

NAKA:

H7F38_19400(mftC)

GOB:

Gobs_4936

BSD:	BLASA_4812

MMAR:

MODMU_5392

SEN:	SACE_2389(pqqE)

SACG:

FDZ84_29565(mftC) FDZ84_34715(mftC)

AMQ:	AMETH_4935(pqqE)

AMYC:

CU254_14360(mftC)

AACD:

LWP59_29720(mftC)

APRT:

MUY14_18355(mftC)

AROO:

NQK81_28185(mftC)

ATHM:

L1857_27430(mftC)

ARHD:

VSH64_10205(mftC)

PDX:

PSEA:

PSEH:

PSEQ:

PECQ:

PHH:	AFB00_13925

PAUT:

Pdca_61410

PBRO:

HOP40_10800(mftC)

PPEL:

H6H00_10965(mftC)

KBU:	Q4V64_47345(mftC)

ALO:

CRK56114

PMAD:

BAY61_06015

ACTY:

OG774_15450(mftC)

ASE:	ACPL_6044(pqqE)

AMS:	AMIS_27220

ACTS:

ACWT_5912

ACTL:

L3i22_048340

CATI:

CS0771_62030

EKE:	EK0264_07230(mftC)

RXY:

Rxyl_3154

RRD:	RradSPS_2636

SBAE:

DSM104329_01719(mftC)

AYM:	YM304_35130

AQZ:	KSP35_11420(mftC)

IAM:	HC251_02955(mftC)

DHI:	LH044_09590(mftC)

PMET:

G4Y79_04760

TRO:

trd_A0840

STI:

Sthe_2856

BHC:	JFL75_07965

MSEA:

METESE_08880

MICA:

P0L94_00205(mftC)

MAQE:

RJ40_11280

MFK:	E2N92_11570

» show all

Reference

PMID:21223593

Authors

Haft DH.

Title

Bioinformatic evidence for a widely distributed, ribosomally produced electron carrier precursor, its maturation proteins, and its nicotinoprotein redox partners.

Journal

BMC Genomics 12:21 (2011)
DOI:10.1186/1471-2164-12-21

Sequence

[mtu:Rv0693]

Reference

PMID:28634235

Authors

Khaliullin B, Ayikpoe R, Tuttle M, Latham JA

Title

Mechanistic elucidation of the mycofactocin-biosynthetic radical S-adenosylmethionine protein, MftC.

Journal

J Biol Chem 292:13022-13033 (2017)
DOI:10.1074/jbc.M117.795682

Sequence

[mul:MUL_0773]

LinkDB

DBGET integrated database retrieval system