KEGG ORTHOLOGY: K25112

ORTHOLOGY: K25112

Entry

K25112                      KO

Symbol

TMX2

Name

thioredoxin-related transmembrane protein 2

Disease

H02461

Neurodevelopmental disorder with microcephaly

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K25112  TMX2; thioredoxin-related transmembrane protein 2
Membrane trafficking [BR:ko04131]
Protein recycling
  Others
   Others
    K25112  TMX2; thioredoxin-related transmembrane protein 2

Other DBs

TC:

1.I.1.1.3

Genes

HSA:	51075(TMX2)

PTR:	107967091(TMX2)

PPS:	100992470(TMX2)

GGO:	101142323(TMX2)

PON:	100174226(TMX2)

NLE:	100585868(TMX2)

HMH:	116468809(TMX2)

MCC:	100169970(TMX2)

MCF:	101865953(TMX2)

MTHB:

126936104

MNI:	105496073(TMX2)

CSAB:

103235319(TMX2)

CATY:

105600783(TMX2)

PANU:

101015532(TMX2)

TGE:	112605821(TMX2)

MLEU:

105552860(TMX2)

RRO:	104677683(TMX2)

RBB:	108514845(TMX2)

TFN:	117079998(TMX2)

PTEH:

111544859(TMX2)

CANG:

105527178(TMX2)

CJC:	100389700(TMX2)

SBQ:	101052825(TMX2)

CIMI:

108282937(TMX2)

CSYR:

103257788(TMX2)

MMUR:

105863132(TMX2)

LCAT:

123642708(TMX2)

PCOQ:

105810040(TMX2)

OGA:	100953213(TMX2)

MMU:	66958(Tmx2)

MCAL:

110288212(Tmx2)

MPAH:

110318726(Tmx2)

RNO:	295701(Tmx2)

MCOC:

116090398(Tmx2)

ANU:	117703975(Tmx2)

MUN:	110551973(Tmx2)

CGE:	100755000(Tmx2)

MAUA:

101823867(Tmx2)

PROB:

127222334(Tmx2)

PLEU:

114710099(Tmx2)

MORG:

121439344(Tmx2)

MFOT:

126487882

AAMP:

119818892(Tmx2)

NGI:	103736641(Tmx2)

HGL:	101720299(Tmx2)

CPOC:

100735434(Tmx2)

CCAN:

109685556(Tmx2)

DORD:

105995504(Tmx2)

DSP:	122105077(Tmx2)

PLOP:

125339289 125361486(Tmx2)

NCAR:

124960508

MMMA:

107135845(Tmx2)

OCU:

100351223

OPI:	101534859(TMX2)

TUP:	102492500(TMX2)

GVR:	103596318(TMX2)

CFA:	475964(TMX2)

CLUD:

112663385(TMX2)

VVP:	112930477(TMX2)

VLG:	121472046(TMX2)

NPO:	129494116(TMX2)

AML:	100479249(TMX2)

UMR:	103666122(TMX2)

UAH:	113246410(TMX2)

UAR:	123785064(TMX2)

ELK:

111150145

LLV:

125078480

MPUF:

101690360(TMX2)

MNP:	132021088(TMX2)

MLK:	131812844(TMX2)

NVS:	122912943(TMX2)

ORO:	101366514(TMX2)

EJU:	114215263(TMX2)

ZCA:	113915439(TMX2)

MLX:	118015868(TMX2)

NSU:	110575828(TMX2)

LWW:	102727571(TMX2)

FCA:	101095680(TMX2)

PYU:	121043400(TMX2)

PBG:	122483789(TMX2)

PVIV:

125176399(TMX2)

LRUF:

124505664

PTG:	102961620(TMX2)

PPAD:

109246461(TMX2)

PUC:

125933471

AJU:

106979562

HHV:	120240383(TMX2)

BTA:	509244(TMX2)

BOM:	102272823(TMX2)

BIU:	109569808(TMX2)

BBUB:

102393156(TMX2)

BBIS:

104984024(TMX2)

CHX:	102172174(TMX2)

OAS:	101106281(TMX2)

BTAX:

128060275(TMX2)

ODA:	120877082(TMX2)

CCAD:

122449715(TMX2)

MBEZ:

129554863(TMX2)

SSC:	100520175(TMX2)

CFR:	102515965(TMX2)

CBAI:

105066930(TMX2)

CDK:	105101221(TMX2)

VPC:	102528813(TMX2)

BACU:

103007466(TMX2)

BMUS:

118899643(TMX2)

LVE:	103088550(TMX2)

OOR:	101284791(TMX2)

DLE:	111183933(TMX2)

PCAD:

102977479(TMX2)

PSIU:

116758711(TMX2)

NASI:

112402444(TMX2)

ECB:	100067021(TMX2)

EPZ:	103558234(TMX2)

EAI:	106822558(TMX2)

MYB:	102246838(TMX2)

MYD:	102762847(TMX2)

MMYO:

118665003(TMX2)

MLF:	102426084(TMX2)

PKL:	118712669(TMX2)

EFUS:

103302290(TMX2)

MNA:	107527705(TMX2)

DRO:	112320314(TMX2)

SHON:

118982778(TMX2)

AJM:	119062331(TMX2) 119063431

PDIC:

114499588(TMX2)

PHAS:

123831487(TMX2)

MMF:	118628331(TMX2)

PPAM:

129062644(TMX2)

HAI:	109371658(TMX2)

RFQ:	117030708(TMX2)

PALE:

102887047(TMX2)

PGIG:

120600818(TMX2)

PVP:	105304742(TMX2)

RAY:	107518396(TMX2)

MJV:	108402315(TMX2)

TOD:	119255263(TMX2)

SARA:

101545010(TMX2)

SETR:

126017823(TMX2)

LAV:	100658527(TMX2)

TMU:

101360897

ETF:	101652887(TMX2)

DNM:	101441544(TMX2)

MDO:	100022953(TMX2)

GAS:	123252105(TMX2)

SHR:	100930909(TMX2)

AFZ:

127541118

PCW:	110199608(TMX2)

OAA:	100090181(TMX2)

GGA:	428853(TMX2)

PCOC:

116229061(TMX2)

MGP:	100547378(TMX2)

CJO:	107314423(TMX2)

TPAI:

128085496(TMX2)

LMUT:

125695392(TMX2)

NMEL:

110401993(TMX2)

APLA:

110353548(TMX2)

CATA:

118249729(TMX2)

AFUL:

116489835(TMX2)

TGU:	100218137(TMX2)

LSR:	110467567(TMX2)

SCAN:

103822279(TMX2)

PMOA:

120500994(TMX2)

OTC:	121334800(TMX2)

PRUF:

121352359(TMX2)

GFR:	102032349(TMX2)

FAB:	101819360(TMX2)

OMA:	130254148(TMX2)

PHI:	102109137(TMX2)

PMAJ:

107205514(TMX2)

CCAE:

111942776(TMX2)

CCW:	120410036(TMX2)

CBRC:

103613045(TMX2)

ETL:	114063292(TMX2)

ZAB:	102065618(TMX2)

SVG:	106854715(TMX2)

MMEA:

130581678(TMX2)

HRT:	120753847(TMX2)

FPG:	101915923(TMX2)

FCH:	102057086(TMX2)

CLV:	102092126(TMX2)

EGZ:	104129565(TMX2)

NNI:	104010535(TMX2)

PLET:

104624888(TMX2)

ACUN:

113480961(TMX2)

TALA:

116959821(TMX2)

AFOR:

103908514(TMX2)

ACHC:

115351938(TMX2)

HLE:	104832059(TMX2)

AGEN:

126047041

GCL:

127016883

MUI:	104539787(TMX2)

LDI:	104339778(TMX2)

OHA:	104336322(TMX2)

SHAB:

115607106(TMX2)

DPUB:

104297500(TMX2)

CPEA:

104389228(TMX2)

CVF:	104295610(TMX2)

RTD:	128908100(TMX2)

CUCA:

104062062(TMX2)

AAM:	106489133(TMX2)

AROW:

112971777(TMX2)

NPD:	112948037(TMX2)

DNE:	112991701(TMX2)

ASN:	102368227(TMX2)

AMJ:	102572457(TMX2)

CPOO:

109318137(TMX2)

GGN:	109295702(TMX2)

PSS:	102462704(TMX2)

CMY:	102933138(TMX2)

CCAY:

125637804(TMX2)

DCC:	119857090(TMX2)

CPIC:

101934519(TMX2)

TST:	117873126(TMX2)

CABI:

116822152(TMX2)

MRV:	120403779(TMX2)

ACS:	100555774(tmx2)

ASAO:

132772871(TMX2)

PVT:	110078329(TMX2)

SUND:

121928519(TMX2)

PBI:	103049552(TMX2)

PMUR:

107295693(TMX2)

CTIG:

120307030(TMX2)

TSR:	106541469(TMX2)

PGUT:

117667113(TMX2)

APRI:

131205070(TMX2)

PTEX:

113448891(TMX2)

NSS:	113422684(TMX2)

VKO:	123018578(TMX2)

PMUA:

114601192(TMX2)

PRAF:

128418489(TMX2)

ZVI:	118089741(TMX2)

HCG:	128334453(TMX2)

GJA:	107108967(TMX2)

STOW:

125425845(TMX2)

EMC:	129325155(TMX2)

XLA:	734381(tmx2.S)

XTR:	448502(tmx2)

NPR:	108794649(TMX2)

RTEM:

120909282(TMX2)

BBUF:

121004219(TMX2)

BGAR:

122940653(TMX2)

MUO:	115456819(TMX2)

GSH:	117348349(TMX2)

DRE:	415203(tmx2b) 561718(tmx2a)

SRX:	107730509 107737795 107746515

SANH:

107664575 107674258 107676789

SGH:	107551492 107556817 107559607

CCAR:

109049983(tmx2) 109101783

CAUA:

113057852 113073012 113076173 113095111

CGIB:

127948866 128017166 128027387

PTET:

122335383(tmx2a) 122341428 122345146(tmx2b)

LROH:

127157962(tmx2a) 127166929(tmx2b)

OMC:	131549678(tmx2b) 131553756(tmx2a)

PPRM:

120460612(tmx2a) 120491787(tmx2b)

RKG:	130075729(tmx2b) 130084795(tmx2a)

MAMB:

125259219(tmx2a) 125272202(tmx2b)

CIDE:

127494134 127517351

MASI:

127413244 127417866 127443770 127444595

TROS:

130552629(tmx2b) 130564120(tmx2a)

TDW:	130414273(tmx2b) 130437889(tmx2a)

MANU:

129422376(tmx2a) 129444296(tmx2b)

IPU:	108262791(tmx2b) 108268686(tmx2a)

IFU:	128605978(tmx2b) 128611892(tmx2a)

PHYP:

113539405(tmx2) 113542835

SMEO:

124385968(tmx2a) 124399217(tmx2b)

TFD:	113642467(tmx2b) 113647716(tmx2a)

TVC:	132847565(tmx2b) 132855989(tmx2a)

AMEX:

103037770 103047312(tmx2)

CMAO:

118807035(tmx2a) 118810545(tmx2b)

EEE:	113570732 113571511

CHAR:

105888929 122130556

TRU:	101065001 101065232 115252291

TFS:	130527910(tmx2b) 130530917(tmx2a)

TNG:	GSTEN00024608G001 GSTEN00036894G001

LCO:	104922635(tmx2) 104937882

NCC:	104951304(tmx2)

TBEN:

117481051(tmx2b) 117487924(tmx2a)

CGOB:

115010798 115014653(tmx2)

PGEO:

117453507(tmx2a) 117455558(tmx2b)

GACU:

117555892(tmx2a) 117556490

EMAC:

134859636(tmx2a) 134864145(tmx2b)

ELY:	117254619(tmx2b) 117260496(tmx2a)

EFO:	125886258(tmx2b) 125894415(tmx2a)

PLEP:

121941488(tmx2b) 121947755(tmx2a)

SLUC:

116052417(tmx2a) 116060629(tmx2b)

ECRA:

117951183(tmx2a) 117960451(tmx2b)

ESP:	116694706 116696341(tmx2)

PFLV:

114547859 114562314(tmx2)

GAT:	120816952(tmx2a) 120824855(tmx2b)

PPUG:

119210523(tmx2a) 119217413

AFB:	129089654(tmx2a) 129095733(tmx2b)

CLUM:

117736153(tmx2b) 117737886(tmx2a)

PSWI:

130210222(tmx2a)

MSAM:

119888757(tmx2a) 119899848(tmx2b)

SCHU:

122874110(tmx2b) 122880718(tmx2a)

CUD:	121508377(tmx2b) 121515915(tmx2a)

ALAT:

119007570(tmx2a) 119025456(tmx2b)

MZE:	101463798(tmx2) 101481687 112429997

ONL:	100701608 100706378(tmx2)

OAU:	116329498(tmx2b) 116332896(tmx2a)

OLA:	101158084 101158207(tmx2)

OML:	112153627(tmx2a) 112157082

CSAI:

133447068(tmx2a) 133447775

XMA:	102233014 102234127(tmx2)

XCO:	114139248(tmx2) 114144417

XHE:	116714734(tmx2) 116719739

PRET:

103470774 103471365(tmx2)

PFOR:

103146641 103147479(tmx2)

PLAI:

106935343(tmx2) 106963787

PMEI:

106905525(tmx2) 106932676

GAF:	122830063(tmx2b) 122836670

PPRL:

129362953(tmx2a)

CVG:	107085674(tmx2) 107103307

CTUL:

119779886 119788327(tmx2a)

GMU:	124860012(tmx2a) 124868552(tmx2b)

NFU:	107376819(tmx2) 107382362

KMR:	108243049(tmx2a)

ALIM:

106516474(tmx2)

NWH:	119408443(tmx2a)

AOCE:

111568507 111576493(tmx2)

MCEP:

125003761 125007859(tmx2a)

CSEM:

103383307 103390955(tmx2)

POV:	109626263(tmx2) 109627381

SSEN:

122770893(tmx2b) 122778543(tmx2a)

HHIP:

117769054(tmx2a) 117774789(tmx2b)

HSP:	118111925(tmx2a) 118118812(tmx2b)

SMAU:

118312461(tmx2b) 118319607(tmx2a)

LCF:	108885556 108888443(tmx2b) 108888633

SDU:	111230457 111232406(tmx2)

SLAL:

111647612 111662750(tmx2)

XGL:	120785015(tmx2a) 120800164(tmx2b)

HCQ:	109524239(tmx2)

SSCV:

125986179

SBIA:

133508937(tmx2a)

PEE:	133407381(tmx2a)

PTAO:

133484960(tmx2a)

BPEC:

110163090(tmx2) 110167603

MALB:

109955485(tmx2) 109975011

BSPL:

114851928 114863964(tmx2a)

SJO:	128362477(tmx2a) 128374027(tmx2b)

SASA:

106602574(TXD14) 106604663 106609908(TXD14) 106611665

STRU:

115191880 115202147 115205196

OTW:	112231820 112256258 112261379

OMY:	110488832(tmx2a) 110497448 110505039 110534429

OGO:	123993427(tmx2a) 124001698 124010609 124013040

ONE:	115129474 115137713 115145785

OKI:	109894151 109901143 109905205

OKE:	118362968 118363508 118384033(tmx2a) 118395440

SALP:

111965749 111967503 111971631 112080846

SNH:	120035012(tmx2b) 120047446 120051981 120062291

CCLU:

121533815 121560108 121562281

ELS:	105022872 105028673(tmx2)

SFM:	108935941(tmx2)

PKI:	111834196 111861071

AANG:

118227736(tmx2b)

LOC:	102688989(tmx2)

PSPA:

121302273(tmx2b)

ARUT:

117410245(tmx2b) 117970869

PSEX:

120538163(tmx2b)

LCM:	102349889(TMX2)

PMRN:

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

AJC:

SKO:

DME:	Dmel_CG11007(CG11007)

DER:

6547409

DSE:

6609959

DSI:	Dsimw501_GD11463(Dsim_GD11463)

DYA:	Dyak_GE12061

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:	26528753 6640786

DGR:

6568731

DMO:	Dmoj_GI18970

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:	108369022 108378331

AOQ:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

109409335 109419089 115258647

CQU:	CpipJ_CPIJ000873

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_204615

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:	105391934 105398803

PGW:

CFEL:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:	103508407 103522142

CLEC:

HHAL:

NLU:

HVI:

MQU:	129001455 129001507

PHU:	Phum_PHUM361780

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_300330

DMK:

DPZ:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

EAF:

TCF:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

CEL:	CELE_C35D10.10(C35D10.10)

CBR:

CBG_17959

CRQ:	GCK72_010004

NAI:	NECAME_00857

BMY:	BM_BM14116(Bm14116)

LOA:	LOAG_10749

TSP:

Tsp_02096

HRO:	HELRODRAFT_194375

LGI:	LOTGIDRAFT_204701

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CVN:	111133856 111136613

CANU:

OED:

MYI:

PMAX:

RPHI:

DPOL:

OBI:

OSN:	115212960 118760971

LAK:

106169659

SMM:	Smp_004170

SHX:	MS3_00006409(TMX2)

OVI:	T265_13109

EGL:

NVE:

EPA:

ATEN:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

TAD:	TRIADDRAFT_59737

ATH:

AT5G11640

ALY:

9307553

CRB:

17882200

CSAT:

104705432 104735176 104769398

EUS:	EUTSA_v10014470mg

BRP:	103846703 103850788

BNA:	106372398 106383017 106383602 106424503

BOE:	106313901 106324874

RSZ:	108839815 130506623

THJ:

104808485

CPAP:

110812415

CIT:

102630344

CIC:	CICLE_v10009282mg

PVY:

MINC:

TCC:

GRA:

GHI:	107906964 107943492

GAB:

108481060

HSYR:

120150958 120193818 120206377

DZI:

EGR:

GMX:

GSJ:

PVU:	PHAVU_001G063300g

VRA:

VAR:

VUN:

VUM:

CCAJ:

APRC:

MTR:

TPRA:

CAM:

PSAT:

VVO:

LJA:	Lj0g3v0096159.1(Lj0g3v0096159.1)

ADU:

107495180

AIP:

107605196

AHF:	112755419 112755568

LANG:

109350688

PCIN:

129294712

QSA:	O6P43_019486

FVE:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:

MSYL:

PXB:

ZJU:

MNT:

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

JCU:

HBR:

MESC:

POP:

PEU:

PALZ:

JRE:

CILL:

CAVE:

QSU:

QLO:

TWL:

VVI:

VRI:

SLY:

SPEN:

SOT:

SSTN:

SDUL:

CANN:

LBB:

NTA:	107779830 107795253

NSY:

NTO:

NAU:

INI:

ITR:

SIND:

OEU:

EGT:

SSPL:

SMIL:

SHIS:

APAN:

HAN:

ECAD:

LSV:

CCAV:

DCR:

CSIN:

RVL:

AEW:

BVG:

SOE:

CQI:	110703813 110705558

ATRI:

MOF:

MING:

TSS:

PSOM:

OSA:

DOSA:

Os01t0200400-01(Os01g0200400)

OBR:

OGL:

BDI:

ATS:

TDC:	119267460 119275370

TAES:

123060591 123069185 123077710

TUA:	125543139 125543147

LPER:

LRD:

SBI:

ZMA:

SITA:

SVS:

PVIR:

PHAI:

112872984 112893363 112903538

PDA:

103710243

EGU:

105048069

MUS:

103968861

ZOF:	122020598 122052048

DCT:

PEQ:

AOF:

MSIN:

NCOL:

ATR:

SMO:	SELMODRAFT_422846

CRE:	CHLRE_10g426400v5

VCN:	VOLCADRAFT_96764

MNG:

MNEG_2500

CVR:	CHLNCDRAFT_59562

OLU:	OSTLU_6169

OTA:	OT_ostta01g02710

BPG:	Bathy15g00550

MIS:	MICPUN_61731

MPP:	MICPUCDRAFT_52828(JGI:MicpuC2_52828)

GSL:	Gasu_29010

MBR:	MONBRDRAFT_25724

SRE:	PTSG_05825

DDI:	DDB_G0286401

DPP:	DICPUDRAFT_80477

DFA:

DFA_11644

PTM:	GSPATT00000673001

PIF:	PITG_18378

PSOJ:

PHYSODRAFT_304137

SPAR:

SPRG_02057

» show all

Reference

PMID:12670024

Authors

Meng X, Zhang C, Chen J, Peng S, Cao Y, Ying K, Xie Y, Mao Y

Title

Cloning and identification of a novel cDNA coding thioredoxin-related transmembrane protein 2.

Journal

Biochem Genet 41:99-106 (2003)
DOI:10.1023/a:1022073917044

Sequence

[hsa:51075]

LinkDB

DBGET integrated database retrieval system