KEGG ORTHOLOGY: K25163

ORTHOLOGY: K25163

Entry

K25163                      KO

Symbol

WAPL

Name

wings apart-like protein

Pathway

map04110

Cell cycle

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K25163  WAPL; wings apart-like protein
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K25163  WAPL; wings apart-like protein
Chromosome and associated proteins [BR:ko03036]
Eukaryotic type
  Meiosis-specific proteins
   Cohesin complex and associated proteins
    K25163  WAPL; wings apart-like protein

Genes

HSA:	23063(WAPL)

PTR:	450568(WAPL)

PPS:	100974515(WAPL)

GGO:	101133816(WAPL)

PON:	100452617(WAPL)

NLE:

115831215

HMH:	116460473(WAPL)

MCC:	700171(WAPL)

MCF:	102126721(WAPL)

MTHB:

126962592

MNI:	105495982(WAPL)

CSAB:

103215878(WAPL)

CATY:

105593678(WAPAL)

PANU:

101006437(WAPL)

TGE:	112631633(WAPL)

MLEU:

105550473(WAPAL)

RRO:	104654592(WAPL)

RBB:	108542976(WAPL)

TFN:	117082805(WAPL)

PTEH:

111551963(WAPL)

CANG:

105517752(WAPAL)

CJC:

100408201

SBQ:	101028942(WAPAL)

CIMI:

108289174(WAPL)

CSYR:

103262481(WAPL)

MMUR:

105884268(WAPL)

LCAT:

123650315(WAPL)

PCOQ:

105815975(WAPAL)

OGA:	100956056(WAPL)

MMU:	218914(Wapl)

MCAL:

110309689(Wapl)

MPAH:

110326029(Wapl)

RNO:	290577(Wapl)

MCOC:

116085359(Wapl)

ANU:	117705159(Wapl)

MUN:	110548020(Wapl)

CGE:	100752368(Wapl)

MAUA:

101840118(Wapl)

PROB:

127238253(Wapl)

PLEU:

114699328(Wapl)

MORG:

121454952(Wapl)

MFOT:

126500574

AAMP:

119827231(Wapl)

NGI:	103726807(Wapl)

HGL:	101702640(Wapl)

CPOC:

100726455(Wapl) 100728918

CCAN:

109684772(Wapl)

DORD:

105997606(Wapal)

DSP:	122116471(Wapl)

PLOP:

125346534(Wapl)

NCAR:

124984828

MMMA:

107154445(Wapl)

OCU:

100348678

OPI:	101536666(WAPL)

TUP:	102481951(WAPL)

GVR:	103588596(WAPAL)

CFA:	612854(WAPL)

CLUD:

112651209(WAPL)

VVP:	112925159(WAPL)

VLG:	121487185(WAPL)

NPO:	129509532(WAPL)

AML:	100475548(WAPL)

UMR:	103667878(WAPL)

UAH:	113259244(WAPL)

UAR:	123783121(WAPL)

ELK:

111145126

LLV:

125084606

MPUF:

101683121(WAPAL)

MNP:	132016561(WAPL)

MLK:	131828747(WAPL)

NVS:	122900855(WAPL)

ORO:	101384362(WAPAL)

EJU:	114205280(WAPL)

ZCA:	113923390(WAPL)

MLX:	118022489(WAPL)

NSU:	110589327(WAPL)

LWW:	102727533(WAPL)

FCA:	101084992(WAPL)

PYU:	121036889(WAPL)

PCOO:

112854418(WAPL)

PBG:	122492932(WAPL)

PVIV:

125147739(WAPL)

LRUF:

124506947

PTG:	102970845(WAPL)

PPAD:

109264515(WAPL)

PUC:

125932781

AJU:

106982653

HHV:	120232784(WAPL)

BTA:	534322(WAPL)

BOM:	102268676(WAPL)

BIU:	109553760(WAPL)

BBUB:

102416592(WAPL)

BBIS:

104999049(WAPAL)

CHX:	100861086(WAPL)

OAS:	101114585(WAPL)

BTAX:

128047395(WAPL)

ODA:	120865168(WAPL)

CCAD:

122446253(WAPL)

MBEZ:

129555650(WAPL)

SSC:	100157544(WAPL)

CFR:	102508292(WAPL)

CBAI:

105075315(WAPAL)

CDK:	105096588(WAPL)

VPC:	102537035(WAPL)

BACU:

103006650(WAPL)

BMUS:

118882469(WAPL)

LVE:	103090149(WAPAL)

OOR:	101285187(WAPL)

DLE:	111168744(WAPL)

PCAD:

102983697(WAPL)

PSIU:

116741458(WAPL)

NASI:

112390473(WAPL)

ECB:	100052524(WAPL)

EPZ:	103550408(WAPL)

EAI:	106831362(WAPL)

MYB:	102255703(WAPL)

MYD:	102770877(WAPL)

MMYO:

118679382(WAPL)

MLF:	102438445(WAPL)

PKL:	118732188(WAPL)

EFUS:

103292809(WAPL)

MNA:	107538482(WAPL)

DRO:	112305297(WAPL)

SHON:

118989308(WAPL)

AJM:	119062404(WAPL)

PDIC:

114496634(WAPL)

PHAS:

123820888(WAPL)

MMF:	118632789(WAPL)

PPAM:

129076290(WAPL)

HAI:	109392220(WAPL)

RFQ:	117035918(WAPL)

PALE:

102889083(WAPL)

PGIG:

120609613(WAPL)

PVP:	105288912(WAPL)

RAY:	107509893(WAPL)

MJV:	108388060(WAPL)

TOD:	119234873(WAPL)

SARA:

101537984(WAPAL)

SETR:

126033654(WAPL)

LAV:	100665918(WAPL)

TMU:

101342033

ETF:	101654114(WAPL)

DNM:	101427644(WAPL)

MDO:	100013552(WAPL)

GAS:	123233002(WAPL)

SHR:	100929095(WAPL)

AFZ:

127552027

PCW:	110213995(WAPL)

OAA:	100085870(WAPL)

GGA:	423608(WAPL)

PCOC:

116234700(WAPL)

MGP:	100546200(WAPL)

CJO:	107315546(WAPL)

TPAI:

128077480(WAPL)

LMUT:

125692967(WAPL)

NMEL:

110400067(WAPL)

APLA:

101799444(WAPL)

ACYG:

106031763(WAPL)

CATA:

118260296(WAPL)

AFUL:

116491437(WAPL)

TGU:	100220310(WAPL)

LSR:	110473564(WAPL)

SCAN:

103814048(WAPL)

PMOA:

120507305(WAPL)

OTC:	121336056(WAPL)

PRUF:

121357845(WAPL)

GFR:	102033311(WAPL)

FAB:	101812906(WAPL)

OMA:	130255218(WAPL)

PHI:	102107104(WAPL)

PMAJ:

107206675(WAPL)

CCAE:

111931572(WAPL)

CCW:	104690185(WAPL)

CBRC:

103623655(WAPL)

ETL:	114064672(WAPL)

ZAB:	102074198(WAPL)

ACHL:

103811340(WAPAL)

SVG:	106854207(WAPL)

MMEA:

130576621(WAPL)

HRT:	120755561(WAPL)

FPG:	101918211(WAPL)

FCH:	102060116(WAPL)

CLV:	102096870(WAPL)

EGZ:	104135417(WAPAL)

NNI:	104013452(WAPAL)

PCRI:

104037145(WAPAL)

PLET:

104628738(WAPAL)

ACUN:

113481813(WAPL)

TALA:

104359037(WAPL)

PADL:

103925851(WAPAL)

AFOR:

103893327(WAPL)

ACHC:

115348394(WAPL)

HALD:

104313776(WAPAL)

HLE:	104831953(WAPAL)

AGEN:

126042647

GCL:

127018103

CCRI:

104161772(WAPAL)

CSTI:

104555322(WAPAL)

CMAC:

104480329(WAPAL)

MUI:	104548440(WAPAL)

BREG:

104636468(WAPAL)

GSTE:

104254050(WAPAL)

LDI:	104350153(WAPAL)

OHA:	104329939(WAPAL)

NNT:	104411921(WAPAL)

SHAB:

115609109(WAPL)

DPUB:

104301332(WAPAL)

ACAR:

104522353(WAPL)

CPEA:

104391780(WAPAL)

AVIT:

104275364(WAPAL)

CVF:	104293521(WAPAL)

RTD:	128911667(WAPL)

CUCA:

104067602(WAPAL)

TEO:	104372353(WAPAL)

AAM:	106499863(WAPL)

AROW:

112968112(WAPL)

NPD:	112950531(WAPL)

TGT:	104565604(WAPAL)

DNE:	112993291(WAPL)

SCAM:

104151265(WAPAL)

ASN:	102375455(WAPL)

AMJ:	102569940(WAPL)

CPOO:

109324065(WAPL)

GGN:	109287293(WAPL)

PSS:	102453862(WAPL)

CMY:	102933927(WAPL)

CCAY:

125639608(WAPL)

DCC:	119858287(WAPL)

CPIC:

101935917(WAPL)

TST:	117879946(WAPL)

CABI:

116822686(WAPL)

MRV:	120368780(WAPL)

ACS:	100553268(wapl)

ASAO:

132771231(WAPL)

PVT:	110085614(WAPL)

SUND:

121925088(WAPL)

PBI:	103064157(WAPL)

PMUR:

107294227(WAPL)

CTIG:

120308001(WAPL)

TSR:	106554041(WAPL)

PGUT:

117676127(WAPL)

APRI:

131200839(WAPL)

PTEX:

113443075(WAPL)

NSS:	113416385(WAPL)

VKO:	123018362(WAPL)

PMUA:

114597136(WAPL)

PRAF:

128413842(WAPL)

ZVI:	118096185(WAPL)

HCG:	128350433(WAPL)

GJA:	107120663(WAPL)

STOW:

125437617(WAPL)

EMC:	129331907(WAPL)

XLA:	108703399(wapl.S) 495199(wapl.L)

XTR:	100170169(wapl)

NPR:	108800010(WAPL)

RTEM:

120908970(WAPL)

BBUF:

121005992(WAPL)

BGAR:

122941409(WAPL)

MUO:	115471288(WAPL)

GSH:	117359211(WAPL)

DRE:	100141368(waplb) 553345(wapla)

SRX:	107716019 107716480 107721422 107745560

SANH:

107654856 107659261 107660482 107678383

SGH:	107571690 107582804 107590871

CCAR:

109056914

CAUA:

113070371 113072476 113075002 113092982 113111871 113117431

CGIB:

127933363 127968888 127976066 128024922

PTET:

122355768 122355770 122361906(wapla)

LROH:

127173945(waplb) 127179833(wapla)

OMC:	131523573(wapla) 131550730(waplb)

PPRM:

120492827 120494052(wapla)

RKG:	130070199(waplb) 130073449(wapla)

MAMB:

125255870(waplb) 125268818(wapla)

CIDE:

127498941 127523465

MASI:

127410648 127423470 127427098 127455277

TROS:

130559937(wapla) 130569186(waplb)

TDW:	130436468(wapla) 130438985(waplb)

MANU:

129417626(wapla) 129420613(waplb)

IPU:	108270145(wapla) 108273883(waplb)

IFU:	128613237(wapla)

PHYP:

113535272 113547727

SMEO:

124388756(waplb) 124390148(wapla)

TFD:	113641437 113662529(waplb) 125145973(wapla)

TVC:	132840510(waplb) 132852030(wapla)

AMEX:

103045703(wapl)

CMAO:

118809665(waplb) 118823509(wapla)

EEE:	113582707 113592265(wapl)

CHAR:

105893441(wapla) 105901302(waplb)

TRU:	101062448 101076637

TFS:	130528281(waplb) 130533852(wapla)

TNG:	GSTEN00004110G001 GSTEN00031558G001

LCO:	104928154 104931501(wapl)

NCC:

104946543

TBEN:

117497650 117499642(wapla)

CGOB:

115005955 115019890

PGEO:

117459592(wapla)

GACU:

117560804(wapla)

EMAC:

134858792(wapla) 134871038

ELY:	117247093(waplb) 117248438(wapla)

EFO:	125880626(waplb) 125903595(wapla)

PLEP:

121954417(wapla) 121958579

SLUC:

116056136(wapla) 116061066(waplb)

ECRA:

117937082(waplb) 117960479(wapla)

ESP:	116671005 116705086(wapl)

PFLV:

114548108 114572402(wapl)

GAT:	120819633 120820671(wapla)

PPUG:

119212961(waplb) 119214183(wapla)

AFB:	129091262 129092357(wapla)

CLUM:

117743822(wapla) 117748337

PSWI:

130203684 130207286(wapla)

MSAM:

119915530 119917183(wapla)

SCHU:

122867556(waplb) 122884454(wapla)

CUD:	121511046(wapla) 121528217(waplb)

ALAT:

119009684 119033660(wapla)

MZE:	101473076 101485449

ONL:	100711254(wapl) 100712474

OAU:	116324706(waplb) 116325736(wapla)

OLA:	101161461 101162153(wapl)

OML:	112154232 112161881(wapla)

CSAI:

133418805(waplb) 133463651(wapla)

XMA:	102218455(wapl) 102226068

XCO:	114138297(wapl) 114152019

XHE:	116713535(wapl) 116727074

PRET:

103476704 103481872

PFOR:

103133625(wapl) 103147059

PLAI:

106945575(wapl) 106957630

PMEI:

106919261 106921518(wapl)

GAF:	122823015 122842106(wapla)

PPRL:

129359766(wapla) 129367930(waplb)

CVG:	107091708 107094973

CTUL:

119790548(wapla) 119799046

GMU:	124859214(wapla) 124875198(waplb)

NFU:	107375931(wapl)

KMR:	108245502(wapla) 108250252

ALIM:

106510771(wapl) 106528243

NWH:	119412660(wapla) 119424219

AOCE:

111569267 111569400(wapl)

MCEP:

125018891(wapla) 125022345

CSEM:

103387085(wapl)

POV:	109634973(wapl) 109643975

SSEN:

122762535 122781904(wapla)

HHIP:

117752647(waplb) 117775442(wapla)

HSP:	118100395 118118981(wapla)

SMAU:

118283743(wapla) 118287183

LCF:	108876830 108897374(wapla)

SDU:	111219567 111235247(wapl)

SLAL:

111663764(wapl) 111664363

XGL:	120794205 120796487(wapla)

HCQ:	109510166(wapl) 109518579

SSCV:

125979001 125991090

SBIA:

133495383 133509837(wapla)

PEE:	133410007(wapla) 133417925

PTAO:

133468935 133485357(wapla)

BPEC:

110157047(wapl) 110162909

MALB:

109960134(wapl) 109962762

BSPL:

114841832(wapla) 114845905

SJO:	128372879(wapla)

SASA:

106578987 106589362 106607591

STRU:

115153256 115157523 115193699 115201129

OTW:	112223482 112224759(waplb) 112254894

OMY:	110491419 110499016 110502510 110529516

OGO:	124040006(waplb) 124041218 124048188

ONE:	115106390 115113194 115135061 115144023

OKI:	109865375 109869933 109889981 109899746

OKE:	118357508 118367963(waplb) 118369763 118399932

SALP:

111967741 111977556 111977893

SNH:	120017678 120029501 120046161 120046574

CCLU:

121536430 121547299 121553782 121571292

ELS:	105006405 105010562(wapl)

SFM:	108932914 108939674

PKI:	111853702(wapl)

AANG:

118218024(wapla) 118220632(waplb)

LOC:	102697217(wapl)

PSPA:

121321751 121325478(waplb)

ARUT:

117415806 117417702(waplb)

PSEX:

120539297(waplb)

LCM:	102346270(WAPL)

CMK:

103181153

RTP:	109914429(waplb)

CPLA:

122541951

HOC:

132835108

LERI:

129712989

PMRN:

116944931(WAPL)

LRJ:	133341804(WAPL)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

SKO:

DME:	Dmel_CG3707(wapl)

DER:

6555580

DSE:

6616095

DSI:	Dsimw501_GD16389(Dsim_wapl)

DYA:	Dyak_GE16974

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI15331

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:

AOQ:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AAG:

AALB:

CQU:	CpipJ_CPIJ018684

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

MDL:

CGLO:

FAS:

DAM:

AGIF:

VCAN:

CCIN:

AROA:

TCA:	663737(wapl)

DPA:

SOY:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_211009

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

HVI:

MQU:

PHU:	Phum_PHUM126310

FOC:

TPAL:

ZNE:

CSEC:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_228144

DMK:

DPZ:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:	126994422 127001760

MNZ:

HAZT:

EAF:

LSM:

TCF:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

PTEP:

ABRU:

UDV:

SDM:

CEL:	CELE_R08C7.10(wapl-1)

CBR:

CBG_01692

CRQ:	GCK72_014616

NAI:	NECAME_06966

BMY:	BM_BM5299(Bma-wapl-1)

LOA:	LOAG_17116

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CVN:

CANU:

MYI:

PMAX:

MMER:

RPHI:

OBI:

OSN:

LAK:	106156423 106170285

SMM:	Smp_152570

SHX:	MS3_00009307

OVI:	T265_15013

EGL:

NVE:

EPA:

ATEN:

ADF:

AMIL:

SPIS:

DGT:

XEN:

HMG:

TAD:	TRIADDRAFT_55864

AQU:

ATH:

ALY:

CRB:

CSAT:

104739739 104755338 104769697

EUS:	EUTSA_v10006765mg

BRP:	103843279 103871874

BNA:	106350069(BNAA06G06790D) 106357951 106416157 106420204

BOE:	106295653 106312736

RSZ:	108814180 108856229

THJ:

104809573

CPAP:

110817858

CIT:

102612111

CIC:	CICLE_v10014178mg

PVY:	116108712 116108725

MINC:

123192560 123218302

TCC:

18596884

GRA:

105773498

GHI:	107901668 107962986

GAB:

108486641

HSYR:

120119425 120146768 120147281 120217213

DZI:	111275068 111278193 111280291

EGR:

104445307

GMX:	100789737 100806542

GSJ:	114375319 114419523

PVU:	PHAVU_002G226800g

VRA:

VAR:

VUN:

VUM:

CCAJ:

APRC:

MTR:

TPRA:

CAM:

PSAT:

VVO:

LJA:	Lj4g3v0450800.1(Lj4g3v0450800.1)

ADU:	107468485 107480587

AIP:	107619980 107631003

AHF:	112714616 112733463 112783363 112791447

LANG:

109331474 109349342

PCIN:

129305939

QSA:	O6P43_012616

FVE:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:	103427850 103446440

MSYL:

PXB:

ZJU:

MNT:

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

JCU:

HBR:	110641689 110643000

MESC:

110604043 110605252

POP:	18102992 7490818

PEU:	105112753 105116963 105128068

PALZ:

118031312 118039512 118047336

JRE:	108982234 108990613

CILL:

CAVE:

QSU:

QLO:

TWL:	119988793 119989438

VVI:

VRI:

SLY:

SPEN:

SOT:

SSTN:

SDUL:

CANN:

LBB:

NTA:	107766628 107783281

NSY:

NTO:

NAU:

INI:

ITR:

SIND:

OEU:

EGT:	105951484 105969183

SSPL:

121775236 121777046 121784816 121787411

SMIL:

130985561 131013382

SHIS:

125209470 125213669

APAN:

127253413

HAN:	110871749 110937881

ECAD:

LSV:

CCAV:

DCR:

CSIN:

RVL:

AEW:	130782232 130795342

BVG:

104900745

SOE:

110786582

CQI:	110693585 110706874

ATRI:

MOF:

NNU:

MING:

TSS:

PSOM:

OSA:

DOSA:

Os10t0497000-01(Os10g0497000)

OBR:

OGL:

BDI:

ATS:

TDC:	119270648 119334688

TAES:

123047433 123122722 123181245

TUA:	125508071 125508095

LPER:

127302535

LRD:	124705766 124705779

SBI:

8065809

ZMA:	100191427 103643407

SITA:

SVS:

PVIR:

PHAI:

PDA:	103698433 103721114 120109106

EGU:

105042809

MUS:	103972100 103985731

ZOF:	121971202 121971205 121976462

DCT:

PEQ:

AOF:

MSIN:

NCOL:

ATR:

SMO:	SELMODRAFT_419261

PPP:

112286865

NGR:	NAEGRDRAFT_68378

» show all

Reference

PMID:15150110

Authors

Oikawa K, Ohbayashi T, Kiyono T, Nishi H, Isaka K, Umezawa A, Kuroda M, Mukai K

Title

Expression of a novel human gene, human wings apart-like (hWAPL), is associated with cervical carcinogenesis and tumor progression.

Journal

Cancer Res 64:3545-9 (2004)
DOI:10.1158/0008-5472.CAN-03-3822

Sequence

[hsa:23063]

Reference

PMID:10747063

Authors

Verni F, Gandhi R, Goldberg ML, Gatti M

Title

Genetic and molecular analysis of wings apart-like (wapl), a gene controlling heterochromatin organization in Drosophila melanogaster.

Journal

Genetics 154:1693-710 (2000)

Sequence

[dme:Dmel_CG3707]

LinkDB

DBGET integrated database retrieval system