KEGG ORTHOLOGY: K25206

ORTHOLOGY: K25206

Entry

K25206                      KO

Symbol

TMEM127

Name

transmembrane protein 127

Disease

H01510

Malignant paraganglioma

Brite

KEGG Orthology (KO) [BR:ko00001]
09190 Not Included in Pathway or Brite
  09193 Unclassified: signaling and cellular processes
   99995 Signaling proteins
    K25206  TMEM127; transmembrane protein 127

Genes

HSA:	55654(TMEM127)

PTR:	740173(TMEM127)

PPS:	100976030(TMEM127)

GGO:	101152216(TMEM127)

PON:	100442976(TMEM127)

PPYG:

129030485(TMEM127)

NLE:	100594796(TMEM127)

HMH:	116483515(TMEM127)

SSYN:

129461865(TMEM127)

MCC:	705069(TMEM127)

MCF:	102119995(TMEM127)

MTHB:

126934330

MNI:	105490032(TMEM127)

CSAB:

103241066(TMEM127)

CATY:

105583718(TMEM127)

PANU:

100998217(TMEM127)

TGE:	112604813(TMEM127)

MLEU:

105531707(TMEM127)

RRO:	104661454(TMEM127)

RBB:	108520917(TMEM127)

TFN:	117099586(TMEM127)

PTEH:

111542232(TMEM127)

CANG:

105522206(TMEM127)

CJC:	100413365(TMEM127)

SBQ:	101048603(TMEM127)

CIMI:

108294720 108301061(TMEM127)

ANAN:

105711883(TMEM127) 105725050

CSYR:

103261398(TMEM127)

MMUR:

105883638(TMEM127)

LCAT:

123637203(TMEM127)

PCOQ:

105808327(TMEM127)

OGA:	100951920(TMEM127)

MMU:	69470(Tmem127)

MCAL:

110287240(Tmem127)

MPAH:

110318001(Tmem127)

RNO:	311405(Tmem127)

MCOC:

116090875(Tmem127)

ANU:	117703073(Tmem127)

ASYL:

127685868(Tmem127)

MUN:	110560921(Tmem127)

CGE:	100758246(Tmem127)

MAUA:

101832010(Tmem127)

PROB:

127221493(Tmem127)

PLEU:

114709077(Tmem127)

MORG:

121460318 121465665

MFOT:

126494396

AAMP:

119814907(Tmem127)

NGI:	103738255(Tmem127)

HGL:	101702991(Tmem127)

CPOC:

100715704(Tmem127)

CCAN:

109683016(Tmem127)

DORD:

105988248(Tmem127)

DSP:	122121317(Tmem127)

DMER:

138821208(Tmem127)

PLOP:

125356066(Tmem127)

NCAR:

124963722

MMMA:

107154138(Tmem127)

ITI:	101959671(Tmem127)

OCU:

100351727

OPI:	101533113(TMEM127)

OCZ:	121165058(TMEM127)

TUP:	102498481(TMEM127)

GVR:	103586605(TMEM127)

CFA:	609057(TMEM127)

CLUD:

112664445(TMEM127)

VVP:	112916619(TMEM127)

VLG:	121491284(TMEM127)

NPO:	129510755(TMEM127)

AML:	100477750(TMEM127)

UMR:	103671883(TMEM127)

UAH:	113241963(TMEM127)

UAR:	123799786(TMEM127)

ELK:

111158433

LLV:

125110048

MPUF:

101675072(TMEM127)

MNP:	132021330(TMEM127)

MLK:	131840471(TMEM127)

NVS:	122915117(TMEM127)

ORO:	101372963(TMEM127)

EJU:	114219625(TMEM127)

ZCA:	113937996(TMEM127)

MLX:	118007826(TMEM127)

NSU:	110587185(TMEM127)

LWW:	102747350(TMEM127)

FCA:	101091188(TMEM127)

PYU:	121044404(TMEM127)

PCOO:

112864064(TMEM127)

PBG:	122497217(TMEM127)

PVIV:

125162158(TMEM127)

LRUF:

124502884

LGF:	123581174(TMEM127)

AJU:

106976049

PTG:	102964238(TMEM127)

PPAD:

109265137(TMEM127)

PUC:

125937484

PLEZ:

122216369(TMEM127)

HHV:	120231598(TMEM127)

BTA:	513620(TMEM127)

BOM:	102282808(TMEM127)

BIU:	109565758(TMEM127)

BBUB:

102400117(TMEM127)

BBIS:

104980801(TMEM127)

CHX:	102173665(TMEM127)

OAS:	101113833(TMEM127)

BTAX:

128055431(TMEM127)

CSUM:

138079675(TMEM127)

ODA:	120883546(TMEM127)

CCAD:

122441360(TMEM127)

MREE:

136164602(TMEM127)

OVR:	110135397(TMEM127)

MBEZ:

129539579(TMEM127)

SSC:	100522794(TMEM127)

CFR:	102511440(TMEM127)

CBAI:

105072170(TMEM127)

CDK:	105092816(TMEM127)

VPC:	102537129(TMEM127)

BACU:

103020218(TMEM127)

BMUS:

118905745(TMEM127)

LVE:	103089236(TMEM127)

OOR:	101269327(TMEM127)

LALB:

132531842(TMEM127)

GMF:	115843165(TMEM127)

DDP:	132435223(TMEM127)

DLE:	111187365(TMEM127)

PCAD:

102982721(TMEM127)

PSIU:

116763958(TMEM127)

PPHC:

136134113(TMEM127)

NASI:

112398889(TMEM127)

ECB:	100062454(TMEM127)

EPZ:	103564058(TMEM127)

EAI:	106842522(TMEM127)

MYB:	102243936(TMEM127)

MYD:	102751841(TMEM127)

MMYO:

118652466(TMEM127) 118668839

MLF:	102434874(TMEM127)

MDT:	132213064(TMEM127)

MYUM:

139020113 139020182

PKL:	118727969(TMEM127)

EFUS:

103299641(TMEM127)

MNA:	107542046(TMEM127)

DRO:	112315137(TMEM127)

SHON:

118992944(TMEM127)

AJM:	119064536(TMEM127)

PDIC:

114499687(TMEM127)

PHAS:

123811488(TMEM127)

MMF:	118630874(TMEM127)

PPAM:

129080450(TMEM127)

HAI:	109392015(TMEM127)

RFQ:	117019294(TMEM127)

PALE:

102887490(TMEM127)

PGIG:

120610263(TMEM127)

PVP:	105306815(TMEM127)

RAY:	107509954(TMEM127)

MJV:	108396935(TMEM127)

TOD:	119259220(TMEM127)

SARA:

101543899(TMEM127)

SFUM:

130031444(TMEM127)

SETR:

126024661(TMEM127)

LAV:	100663556(TMEM127)

TMU:

101345672

ETF:	101663404(TMEM127)

DNM:	101445684(TMEM127)

MDO:	100030922(TMEM127)

GAS:	123234808(TMEM127)

SHR:	100926095(TMEM127)

AFZ:

127548371

PCW:	110209792(TMEM127)

TVP:	118843282(TMEM127)

PBRV:

138151992(TMEM127)

MLAO:

141504300(TMEM127)

OAA:	100085820(TMEM127)

TACU:

119939631(TMEM127)

GGA:	100857207(TMEM127)

PCOC:

116240130(TMEM127)

MGP:	100542880(TMEM127)

CJO:	107323656(TMEM127)

TPAI:

128071856(TMEM127)

LMUT:

125685199(TMEM127)

NMEL:

110387194(TMEM127)

APLA:

101793896(TMEM127)

ACYG:

106048900(TMEM127)

CATA:

118259315(TMEM127)

AFUL:

116499454(TMEM127)

TGU:	115498158(TMEM127)

LSR:	110478276(TMEM127)

PMOA:

120499164(TMEM127)

PRUF:

121355613(TMEM127)

ATRC:

139585174(TMEM127)

OMA:	130261988(TMEM127)

PHI:	102101254(TMEM127)

PMAJ:

107199451(TMEM127)

CCAE:

111945106(TMEM127)

ACOE:

138121728(TMEM127)

ETL:	114069665(TMEM127)

ZLE:	135456992(TMEM127)

ACHL:

103811182(TMEM127)

SVG:	106863964(TMEM127)

MMEA:

130588323(TMEM127)

HRT:	120748285(TMEM127)

CCIC:

134054676(TMEM127)

FPG:	101915672(TMEM127)

FCH:	102058423(TMEM127)

CCRI:

104164334(TMEM127)

SHAB:

115618449(TMEM127)

ACUN:

113490441(TMEM127)

TALA:

116964813(TMEM127)

ACHC:

115349982(TMEM127)

HALD:

104322749(TMEM127)

HLE:	104829005(TMEM127)

AGEN:

126051646

HHAR:

128149918(TMEM127)

AVIT:

104272933(TMEM127)

EGZ:	104123288(TMEM127)

NNI:	104021437(TMEM127)

PCRI:

104027683(TMEM127)

PCAO:

104045727(TMEM127)

FGA:	104075659(TMEM127)

CBOR:

142093497(TMEM127)

CBOY:

140643839(TMEM127)

MAME:

142420143(TMEM127)

CLV:	102085239(TMEM127)

CNIC:

135998481(TMEM127)

MUI:	104535002(TMEM127)

PLET:

104622753(TMEM127)

CUCA:

104067009(TMEM127)

OHA:	104338001(TMEM127)

ACAR:

104532325(TMEM127)

CPEA:

104397474(TMEM127)

CVF:	104285431(TMEM127)

RTD:	128919592(TMEM127)

CRID:

134526716(TMEM127)

LMIC:

141733474(TMEM127)

AAM:	106484273 106486886

AROW:

112975343(TMEM127)

NPD:	112950115(TMEM127)

TGT:	104564634(TMEM127)

DNE:	112995076(TMEM127)

SCAM:

104149046(TMEM127)

ASN:	102368559(TMEM127)

AMJ:	102575502(TMEM127)

CPOO:

109313316(TMEM127)

GGN:	109291295(TMEM127)

PSS:	102453954(TMEM127)

CIZ:	142004380(TMEM127)

CMY:	102944415(TMEM127)

CCAY:

125626440(TMEM127)

DCC:	119848793(TMEM127)

CPIC:

101934921(TMEM127)

TST:	117872858(TMEM127)

CABI:

116815208(TMEM127)

MRV:	120397898(TMEM127)

ACS:	100557988(tmem127)

ASAO:

132782322(TMEM127)

PVT:	110072124(TMEM127)

SUND:

121933263(TMEM127)

PBI:	103062464(TMEM127)

PMUR:

107283691(TMEM127)

CTIG:

120299379 120318786(TMEM127)

TSR:	106548269(TMEM127)

PGUT:

117673392(TMEM127)

APRI:

131203657(TMEM127)

PTEX:

113445865(TMEM127)

NSS:	113426319(TMEM127)

VKO:	123016749(TMEM127)

PMUA:

114602636(TMEM127)

PRAF:

128420080(TMEM127)

ZVI:	118086332(TMEM127)

HCG:	128333691(TMEM127)

GJA:	107118466(TMEM127)

STOW:

125442181(TMEM127)

EMC:	129341945(TMEM127)

XLA:	108711558 447044(tmem127.S)

XTR:	549686(tmem127)

NPR:	108797676(TMEM127)

RTEM:

120933005(TMEM127)

ACAT:

141133006(TMEM127)

BBUF:

120986126(TMEM127)

BGAR:

122929495(TMEM127)

DTC:	141070524(TMEM127)

PWL:	138266067(TMEM127)

MUO:	115469217(TMEM127)

GSH:	117362585(TMEM127)

DRE:	553545(tmem127)

SRX:	107713035 107714579

SANH:

107671030 107699648

SGH:

107552193

CCAR:

109105672(tmem127)

CAUA:

113052712 113052755 113106931

CGIB:

127964146 128019004

PTET:

122350332(tmem127)

LROH:

127170137(tmem127)

GRF:	141287178(tmem127)

OMC:	131545361(tmem127)

PPRM:

120481263(tmem127)

RKG:	130091461(tmem127)

MAMB:

125279378(tmem127)

CIDE:

127518129

CERY:

137026824(tmem127)

MASI:

127415426 127423759

TROS:

130568566(tmem127)

TDW:	130407135(tmem127)

MANU:

129414466(tmem127)

PDAB:

135730352(tmem127)

IPU:

108265579

IFU:	128607757(tmem127)

PHYP:

113524496(tmem127)

SMEO:

124400321(tmem127)

TFD:	113656251(tmem127)

TVC:	132853439(tmem127)

CGAR:

128530790(tmem127)

NGRA:

132893044(tmem127)

TRN:	134317576(tmem127)

AMEX:

103021830(tmem127)

CMAO:

118813468(tmem127)

EEE:	113571061(tmem127)

CHAR:

105894897(tmem127)

SPIL:

134088438(tmem127)

ASAD:

121715044(tmem127)

TRU:	101078124(tmem127)

TFS:	130525516(tmem127)

TNG:	GSTEN00007266G001

LCO:	104934628(tmem127)

NCC:	104961731(tmem127)

TBEN:

117472883(tmem127)

CGOB:

115013141(tmem127)

PGEO:

117452719(tmem127)

GACU:

117543867(tmem127)

EMAC:

134873192(tmem127)

ELY:	117251990(tmem127)

EFO:	125890651(tmem127)

PLEP:

121944217(tmem127)

SLUC:

116054365(tmem127)

ECRA:

117944595(tmem127)

ESP:	116686646(tmem127)

PFLV:

114555773(tmem127)

GAT:	120830241(tmem127)

PPUG:

119224596(tmem127)

AFB:	129101418(tmem127)

CLUM:

117736741(tmem127)

PSWI:

130196245(tmem127)

CANA:

137804925(tmem127)

CVE:	137867466(tmem127)

MSAM:

119891979(tmem127)

SCHU:

122876644(tmem127)

CUD:	121510526(tmem127)

SPUL:

138610400(tmem127)

LMIX:

132974011(tmem127)

HTC:	141791011(tmem127)

ALAT:

119019055(tmem127)

ASTR:

137592674(tmem127)

MZE:	101473885(tmem127)

ONL:	100711836(tmem127)

OAU:	116323863(tmem127)

OLA:	101175169(tmem127)

OML:	112148673(tmem127)

CSAI:

133451006(tmem127)

XMA:	102237441(tmem127)

XCO:	114154043(tmem127)

XHE:	116729147(tmem127)

PRET:

103470570(tmem127)

PFOR:

103146431(tmem127)

PLAI:

106950439(tmem127)

PMEI:

106921247(tmem127)

GAF:	122827881(tmem127)

PPRL:

129373123(tmem127)

CVG:	107104635(tmem127)

CTUL:

119783974(tmem127)

GMU:	124877538(tmem127)

NFU:	107393696(tmem127)

KMR:	108236454(tmem127)

ALIM:

106520118(tmem127)

NWH:	119413496(tmem127)

AOCE:

111580368(tmem127)

EJA:	138191992(tmem127)

BFRE:

138621579(tmem127)

MCEP:

125011609(tmem127)

CSEM:

103397018 103397396

POV:	109633734(tmem127)

SSEN:

122768976(tmem127)

SSOE:

131464253(tmem127)

HHIP:

117767448(tmem127)

HSP:	118115354(tmem127)

PPLT:

128437713(tmem127)

SMAU:

118313492(tmem127)

LCF:

108878387

SDU:	111226136(tmem127)

SLAL:

111645043(tmem127)

XGL:	120804641(tmem127)

HCQ:	109511641(tmem127)

SSCV:

125993542(tmem127)

SBIA:

133499906(tmem127)

PEE:	133400510(tmem127)

PTAO:

133475568(tmem127)

BPEC:

110169871(tmem127)

ENY:	140346724(tmem127)

MALB:

109954988(tmem127)

BSPL:

114862983(tmem127)

SJO:	128365085(tmem127)

SSCO:

133979150(tmem127)

TTY:	137194147(tmem127)

GMH:	115553342(tmem127)

SASA:

106579884(TM127) 106585551(TM127)

STRU:

115164578 115200071

OTW:	112248434 112262966

OMY:	110525613 110535979

OGO:	124034356 124036262

ONE:	115111553 115139990

OKI:	109879091 109895853

OKE:	118358292 118393157

OMM:	135514152 135541015

OCLA:

139389716 139410875

SALP:

111957786 111974050

SNH:	120063204 120066080

SFON:

129826253 129853513

CCLU:

121530850 121584798

ELS:	105027594(tmem127)

OEP:	134011921(tmem127)

SFM:	108938003(tmem127)

PKI:	111856539(tmem127)

AANG:

118206888(tmem127)

AROT:

135233087(tmem127)

CCOG:

133140515(tmem127)

LOC:	102694721(tmem127)

PSPA:

121302373 121303154

ARUT:

117397810 117966136

PSEX:

120539378(tmem127)

LCM:	102358194(TMEM127)

CMK:	103187787(tmem127)

RTP:	109918940(tmem127)

CPLA:

122543088(tmem127)

HOC:	132837016(tmem127)

SCAU:

119957377(tmem127)

LERI:

129713169(tmem127)

HAKA:

140733571(tmem127)

PMRN:

116937841(TMEM127)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

LVG:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

SKO:

PFLL:

TCA:

TMOL:

DPA:

ESIM:

EFOR:

SOY:

AGRG:

ATD:

CSET:

HAXR:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_203149

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ONU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CSTB:

CFUM:

DCI:	103515030 113469855 113473289

CLEC:

HHAL:

NLU:

LDA:

HVI:

MQU:

ZNE:

CSEC:

PAME:

BROR:

IEL:

HAMR:

DPX:	DAPPUDRAFT_312225

DMK:

116921763

PVM:	113802804 113802805

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

MRJ:

PORN:

ISC:

DSV:

RSAN:

RMP:

GOE:

TUT:

DPTE:

CSCU:

CVS:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

LGI:	LOTGIDRAFT_115322

PVUL:

PCAN:

LSAX:

BGT:

GAE:

HRF:	124138110 124138112

HRJ:	124284822 124284823

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

LLON:

NVE:

EPA:

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

HMG:

HSY:

RES:

Reference

PMID:20154675

Authors

Qin Y, Yao L, King EE, Buddavarapu K, Lenci RE, Chocron ES, Lechleiter JD, Sass M, Aronin N, Schiavi F, Boaretto F, Opocher G, Toledo RA, Toledo SP, Stiles C, Aguiar RC, Dahia PL

Title

Germline mutations in TMEM127 confer susceptibility to pheochromocytoma.

Journal

Nat Genet 42:229-33 (2010)
DOI:10.1038/ng.533

Sequence

[hsa:55654]

LinkDB

DBGET integrated database retrieval system