KEGG ORTHOLOGY: K25233

ORTHOLOGY: K25233

Entry

K25233                      KO

Symbol

ambB

Name

L-alanine---[L-alanyl-carrier protein] ligase [EC:6.2.1.67]

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K25233  ambB; L-alanine---[L-alanyl-carrier protein] ligase
Enzymes [BR:ko01000]
6. Ligases
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.67  L-alanine---[L-alanyl-carrier protein] ligase
     K25233  ambB; L-alanine---[L-alanyl-carrier protein] ligase
Polyketide biosynthesis proteins [BR:ko01008]
Nonribosomal peptide synthetase (NRPS)
  Linear NRPS
   L-2-amino-4-methoxy-trans-3-butenoic acid synthetase
    K25233  ambB; L-alanine---[L-alanyl-carrier protein] ligase

Other DBs

COG:

COG1020

Genes

PAE:	PA2305(ambB)

PAEV:

N297_2378(lgrD)

PAEI:

N296_2378(lgrD)

PAU:	PA14_34810(mxaA)

PAG:	PLES_29991

PAF:	PAM18_2735

PNC:	NCGM2_3315(mxaA)

PAEB:

NCGM1900_4225

PDK:	PADK2_13745

PSG:	G655_13525

PAEP:

PAER:

PAEM:

PAEL:

PAES:

PAEU:

PAEG:

PAEC:

PAEO:

SECH:

MHAW:

Reference

PMID:25814981

Authors

Rojas Murcia N, Lee X, Waridel P, Maspoli A, Imker HJ, Chai T, Walsh CT, Reimmann C.

Title

The Pseudomonas aeruginosa antimetabolite L -2-amino-4-methoxy-trans-3-butenoic acid (AMB) is made from glutamate and two alanine residues via a thiotemplate-linked tripeptide precursor.

Journal

Front Microbiol 6:170 (2015)
DOI:10.3389/fmicb.2015.00170

Sequence

[pae:PA2305]

LinkDB

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