KEGG ORTHOLOGY: K25435

ORTHOLOGY: K25435

Entry

K25435                      KO

Symbol

ASMTL

Name

putative bifunctional nucleoside triphosphate pyrophosphatase / methyltransferase [EC:3.6.1.- 2.1.1.-]

Pathway

map00240

Pyrimidine metabolism

map01100

Metabolic pathways

map01232

Nucleotide metabolism

Reaction

R00515

CTP diphosphohydrolase (diphosphate-forming)

R00662

uridine triphosphate pyrophosphohydrolase

R11323

dTTP diphosphohydrolase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    K25435  ASMTL; putative bifunctional nucleoside triphosphate pyrophosphatase / methyltransferase

Genes

HSA:	8623(ASMTL)

PTR:	739415(ASMTL)

PPS:	100991935(ASMTL)

GGO:	101150363(ASMTL)

PON:	100189752(ASMTL)

PPYG:

129025660(ASMTL)

NLE:	105738521(ASMTL)

SSYN:

129475914(ASMTL)

MCC:

106995141

MCF:	102127776 141406856

MTHB:

126946848 126947136

MNI:	105478258(ASMTL)

CSAB:

103247521(ASMTL)

CATY:

105574817(ASMTL)

PANU:

101024698

TGE:	112616384(ASMTL)

MLEU:

105554245(ASMTL)

TFN:	117076065(ASMTL)

CANG:

105500635

CJC:	100387365 128930662

SBQ:	101045614(ASMTL)

CIMI:

108296376(ASMTL)

ANAN:

105710569(ASMTL) 135269930

MMUR:

105870819(ASMTL)

LCAT:

123628070(ASMTL)

ERUF:

138377993(ASMTL)

PCOQ:

105820354(ASMTL)

OGA:	100945794(ASMTL)

HGL:	101704436(Asmtl)

CCAN:

109688725(Asmtl)

DORD:

106000182(Asmtl)

NCAR:

124972226

MMMA:

107160185(Asmtl)

ITI:	101964135(Asmtl)

OCU:

100352740

OPI:	101521300(ASMTL)

OCZ:	121166479 121168550

TUP:	102475198(ASMTL)

GVR:	103586746(ASMTL)

CFA:	609318(ASMTL)

CLUD:

112651972(ASMTL)

VVP:	112908948(ASMTL)

VLG:	121482905(ASMTL)

NPO:	129518675(ASMTL)

AML:	100469251(ASMTL)

UMR:	103666291(ASMTL)

UAH:

113240811

UAR:	123802744(ASMTL)

ELK:

111157121

LLV:

125091649

MPUF:

101670296(ASMTL)

MNP:	132007679(ASMTL)

MLK:	131822208(ASMTL)

NVS:	122897565(ASMTL)

ORO:	101379223(ASMTL)

EJU:	114218081(ASMTL)

ZCA:	113931199(ASMTL)

MLX:	118026669(ASMTL)

NSU:	110579668(ASMTL)

LWW:	102750563(ASMTL)

FCA:	101101111(ASMTL)

PYU:	121020206(ASMTL)

PBG:	122477974(ASMTL)

PVIV:

125159251(ASMTL)

LRUF:

124509314

LGF:	123594897(ASMTL)

AJU:

106982057

PTG:	102965902(ASMTL)

PPAD:

109256145(ASMTL)

PUC:

125932328

PLEZ:

122212620(ASMTL)

HHV:	120240561(ASMTL)

BTA:	132344461 508458(ASMTL)

BOM:	102280403(ASMTL)

BBUB:

102400570(ASMTL)

BBIS:

104982068(ASMTL)

CHX:	102179088(ASMTL)

OAS:

105611964

BTAX:

128069773(ASMTL)

CSUM:

138071135(ASMTL)

ODA:	120882421(ASMTL)

CCAD:

122434352

MREE:

136153212(ASMTL)

OVR:	110129977(ASMTL)

MBEZ:

129534807(ASMTL)

SSC:	110258198(ASMTL)

CFR:	102512624(ASMTL)

CBAI:

105079527(ASMTL)

VPC:	102541745(ASMTL)

BACU:

103009194(ASMTL)

BMUS:

118888924(ASMTL)

LVE:	103086931(ASMTL)

OOR:	101280726(ASMTL)

LALB:

132514068(ASMTL)

GMF:	115842362(ASMTL)

DDP:	132418560(ASMTL)

DLE:	111168266(ASMTL)

PCAD:

102985611(ASMTL)

PSIU:

116746992(ASMTL)

PPHC:

136142635

NASI:

112415224(ASMTL)

EPZ:	103544760(ASMTL)

EAI:	106842516(ASMTL)

MYB:	102248407(ASMTL)

MYD:

102758497

MMYO:

118657292(ASMTL)

MDT:	132224871(ASMTL)

MYUM:

139000561(ASMTL)

EFUS:

114229695(ASMTL)

MNA:	107543959(ASMTL)

DRO:

112313316

SHON:

118974339(ASMTL)

AJM:	119045714(ASMTL)

PDIC:

114489865 114489866 114489869 114489870 114489871 114489872 114489873 114489885 114489896

PHAS:

123829977 123829978 123829979 123829980 123829989 123829990 123829991 123829992

MMF:	118636416(ASMTL)

PPAM:

129079752(ASMTL)

HAI:	109375574(ASMTL)

RFQ:	117035713(ASMTL)

PALE:

102878000(ASMTL)

PGIG:

120599712

PVP:	105308000(ASMTL)

MJV:	108389195(ASMTL)

TOD:	119245759(ASMTL)

SARA:

101543452(ASMTL)

SFUM:

130019010(ASMTL)

SETR:

126000581(ASMTL)

LAV:	100656748(ASMTL)

TMU:

101359050

ETF:	123522370(ASMTL)

DNM:

101437075

MDO:	100010804(ASMTL)

GAS:	123242566(ASMTL)

SHR:	100933575(ASMTL)

AFZ:

127553683

PCW:	110212824(ASMTL)

TVP:	118837248 118838394

PBRV:

138149694(ASMTL)

MLAO:

141506681(ASMTL)

OAA:	100074781(ASMTL)

TACU:

119937659(ASMTL)

GGA:	769097(ASMTL)

PCOC:

116230786(ASMTL)

CJO:	107305863(ASMTL)

TPAI:

128071778(ASMTL)

LMUT:

125688402(ASMTL)

NMEL:

110405883(ASMTL)

APLA:

101794913(ASMTL)

AACU:

137856455(ASMTL)

ACYG:

106035721(ASMTL)

CATA:

118245731(ASMTL)

AFUL:

116490263(ASMTL)

TGU:	105758650(ASMTL)

LSR:	110479347(ASMTL)

SCAN:

103812319(ASMTL)

PMOA:

120510185(ASMTL)

OTC:	121345332(ASMTL)

PRUF:

121354086(ASMTL)

ATRC:

139604153(ASMTL)

GFR:	102038329(ASMTL)

FAB:	101818685(ASMTL)

OMA:	130248365(ASMTL)

PHI:	102112527(ASMTL)

PMAJ:

107201447(ASMTL)

CCAE:

111945741(ASMTL)

CCW:	104686015(ASMTL)

CBRC:

103611791(ASMTL)

ACOE:

138106422(ASMTL)

ETL:	114066991(ASMTL)

ZAB:	102061351(ASMTL)

ZLE:	135447009(ASMTL)

ACHL:

103800544(ASMTL)

SVG:	106862919(ASMTL)

MMEA:

130577910(ASMTL)

HRT:	120748990(ASMTL)

SATI:

136357899(ASMTL)

CFAI:

136285381(ASMTL)

CCIC:

134057956(ASMTL)

FPG:	101917540(ASMTL)

FCH:	102056953(ASMTL)

CCRI:

104166185(ASMTL)

NNT:	104400792(ASMTL)

SHAB:

115604304(ASMTL)

ACUN:

113478666(ASMTL)

SURA:

141939351(ASMTL)

TALA:

104356354(ASMTL)

ACHC:

115334640(ASMTL)

HALD:

104315930(ASMTL)

HLE:	104839872(ASMTL)

AGEN:

126053043

HHAR:

128135111(ASMTL)

BBUT:

142044591(ASMTL)

GCL:

127026668

LDI:	104339988(ASMTL)

MNB:	103768911(ASMTL)

DPUB:

104302127(ASMTL)

PPUS:

135175397(ASMTL)

AVIT:

104269392(ASMTL)

BRHI:

104488289

EGZ:	104125149(ASMTL)

NNI:	104009845(ASMTL)

PCRI:

104025720(ASMTL)

PCAO:

104050926(ASMTL)

PADL:

103923030(ASMTL)

AFOR:

103900636(ASMTL)

FGA:	104073644(ASMTL)

CBOR:

142073882(ASMTL)

GSTE:

104261261(ASMTL)

CBOY:

140646126(ASMTL)

MAME:

142419747(ASMTL)

CLV:	102093979(ASMTL)

CNIC:

136001911(ASMTL)

MUI:	104541450(ASMTL)

PGUU:

104470243

PLET:

104614184(ASMTL)

EHS:	104511530(ASMTL)

CMAC:

104474782

CUCA:

104063720(ASMTL)

TEO:	104381364(ASMTL)

BREG:

104629752(ASMTL)

GAME:

129201661(ASMTL)

OHA:	104326403(ASMTL)

ACAR:

104527130(ASMTL)

CPEA:

104391842(ASMTL)

CVF:	104290364(ASMTL)

RTD:	128915552(ASMTL)

CRID:

134518226(ASMTL)

LMIC:

141751164(ASMTL)

AAM:	106491282(ASMTL)

AROW:

112960573(ASMTL)

NPD:	112944014(ASMTL)

TGT:	104570665(ASMTL)

DNE:	112992414(ASMTL)

SCAM:

104138693(ASMTL)

ASN:	102385205(ASMTL)

AMJ:	102576538(ASMTL)

CPOO:

109306130(ASMTL)

GGN:	109302598(ASMTL)

PSS:	102458570(ASMTL)

CIZ:	142012350(ASMTL)

CMY:	102941189(ASMTL)

CCAY:

125640759(ASMTL)

LKP:	140914923(ASMTL)

NDS:	141995164(ASMTL)

DCC:	119855639(ASMTL)

CPIC:

101937587(ASMTL)

TST:	117870450(ASMTL)

CABI:

116829736(ASMTL)

MRV:	120399546(ASMTL)

ACS:	100556310(asmtl)

ASAO:

132771632(ASMTL)

PVT:	110089752(ASMTL)

SUND:

121926421(ASMTL)

PMUR:

107289683(ASMTL)

CTIG:

120297527(ASMTL)

TSR:	106547815(ASMTL)

PGUT:

117673790(ASMTL)

PCAE:

139316598(ASMTL)

APRI:

131200122(ASMTL)

PTEX:

113440851(ASMTL)

NSS:	113411674(ASMTL)

VKO:	123024729(ASMTL)

PMUA:

114596326(ASMTL)

PRAF:

128413246(ASMTL)

ZVI:	118084910(ASMTL)

HCG:	128350828(ASMTL)

GJA:	107120381(ASMTL)

STOW:

125430487(ASMTL)

EMC:	129326502(ASMTL)

XLA:	444241(asmtl.L)

XTR:	548765(asmtl)

NPR:	108790889(ASMTL)

RTEM:

120927484(ASMTL)

ACAT:

141128848(ASMTL)

PADS:

140341775(ASMTL)

BBUF:

120994860(ASMTL)

BGAR:

122930547(ASMTL)

DTC:	141080596(ASMTL)

PWL:	138250110(ASMTL)

MUO:	115469443(ASMTL)

GSH:	117362522(ASMTL)

DRE:	324134(asmtl)

SRX:	107748137(asmtl)

SANH:

107673687

SGH:

107597490

CCAR:

109070282(asmtl)

CAUA:

113108145 113108478

CGIB:

127965561

PTET:

122352148(asmtl)

LROH:

127171428(asmtl)

GRF:	141340594(asmtl)

OMC:	131547260(asmtl)

PPRM:

120489388(asmtl)

RKG:	130069226(asmtl)

MAMB:

125270148(asmtl)

CIDE:

127519429

CERY:

137035679(asmtl)

MASI:

127447501 127448214

TROS:

130555987(asmtl)

TDW:	130427656(asmtl)

MANU:

129452167(asmtl)

PDAB:

135733398(asmtl)

IPU:

108266971

IFU:	128608763(asmtl)

PHYP:

113546984(asmtl)

SMEO:

124382807(asmtl)

TFD:	113654403(asmtl)

TVC:	132850137(asmtl)

CGAR:

128524274(asmtl)

NGRA:

132891808(asmtl)

TRN:	134324467(asmtl)

AMEX:

103043619(asmtl)

CMAO:

118819531(asmtl)

EEE:	113568051(asmtl)

CHAR:

105905963(asmtl)

SPIL:

134078360(asmtl)

ASAD:

121698412(asmtl)

TRU:	101066859(asmtl)

TFS:	130526046(asmtl)

LCO:	104926305(asmtl)

NCC:

104960522

TBEN:

117481027(asmtl)

CGOB:

115026473(asmtl)

PGEO:

117466951(asmtl)

GACU:

117544515(asmtl)

EMAC:

134867183(asmtl)

ELY:	117251705(asmtl)

EFO:	125899354(asmtl)

PLEP:

121948969(asmtl)

SLUC:

116039529(asmtl)

ECRA:

117952735(asmtl)

ESP:

116698158

PFLV:

114564563

GAT:	120833730(asmtl)

PPUG:

119228382(asmtl)

AFB:	129104770(asmtl)

CLUM:

117750993(asmtl)

PSWI:

130203200(asmtl)

CANA:

137783163(asmtl)

CVE:	137878077(asmtl)

MSAM:

119904378(asmtl)

SCHU:

122885816(asmtl)

CUD:	121523132(asmtl)

SPUL:

138592642(asmtl)

LMIX:

132986657(asmtl)

HTC:	141808824(asmtl)

ALAT:

119025986(asmtl)

ASTR:

137604985(asmtl)

MZE:	101472013(asmtl)

ONL:	100692091(asmtl)

OAU:	116321566(asmtl)

OLA:	101167082(asmtl)

OML:	112155025(asmtl)

CSAI:

133446235 133446248

XMA:	102219166(asmtl)

XCO:	114148578(asmtl)

XHE:	116722819(asmtl)

PRET:

103478993(asmtl)

PFOR:

103134758(asmtl)

PLAI:

106950312(asmtl)

PMEI:

106918901(asmtl)

GAF:	122839983(asmtl)

PPRL:

129361458(asmtl)

CVG:	107091806(asmtl)

CTUL:

119783343(asmtl)

GMU:	124871729(asmtl)

NFU:	107389707(asmtl)

KMR:	108232334(asmtl)

ALIM:

106524830(asmtl)

NWH:	119419296(asmtl)

AOCE:

111584059(asmtl)

EJA:	138201119(asmtl)

BFRE:

138625783(asmtl)

MCEP:

125017306(asmtl)

CSEM:

103391813(asmtl)

POV:	109638014(asmtl)

SSEN:

122765200(asmtl)

SSOE:

131455611(asmtl)

HHIP:

117754795(asmtl)

HSP:	118120344(asmtl)

PPLT:

128455779(asmtl)

SMAU:

118282594(asmtl)

LCF:	108901284(asmtl)

SDU:	111218733(asmtl)

SLAL:

111653848(asmtl)

XGL:	120801898(asmtl)

HCQ:	109510215(asmtl)

SSCV:

125973504(asmtl)

SBIA:

133512045(asmtl)

PEE:	133410829(asmtl)

PTAO:

133486585(asmtl)

BPEC:

110170600(asmtl)

ENY:	140359742(asmtl)

MALB:

109965509(asmtl)

BSPL:

114846849(asmtl)

SJO:	128367740(asmtl)

SSCO:

133992799(asmtl)

TTY:	137192964(asmtl)

GMH:	115533040(asmtl)

SASA:

106586022(asmtl)

STRU:

115160608(asmtl)

OTW:	112234782(asmtl)

OMY:	110519966(asmtl)

OGO:	124043742(asmtl)

ONE:	115107522(asmtl)

OKI:	109865418(asmtl)

OKE:	118367206(asmtl)

OMM:	135519919(asmtl)

OCLA:

139396187

SALP:

111973323(asmtl)

SNH:	120058183(asmtl)

SFON:

129821465(asmtl)

CCLU:

121536619(asmtl)

ELS:	105031342(asmtl)

OEP:	134017635(asmtl)

SFM:	108928380(asmtl)

PKI:	111838444(asmtl)

AANG:

118213948(asmtl)

AROT:

135240456(asmtl)

CCOG:

133116346(asmtl)

LOC:

102687381

PSPA:

121320701 121328015

ARUT:

117405108 117407337

PSEX:

120523444(asmtl)

LCM:	102349285(ASMTL)

CMK:

103177097

RTP:	109914048(asmtl)

CPLA:

122550914(asmtl)

CPUN:

140481157(asmtl)

HOC:	132816869(asmtl)

SCAU:

119977332(asmtl)

LERI:

129697802 129697817

HAKA:

140727027(asmtl)

LRJ:

133357796

PFLL:

139120596 139141268 139146244 139146271

HASI:

HCRA:

CANU:

OED:

YBA:

MCAZ:

138015611 138015669 138015864 138015865 138017093

MFOO:

137998901 137998903 137999681 137999682 138000979

» show all

Reference

PMID:24210219

Authors

Tchigvintsev A, Tchigvintsev D, Flick R, Popovic A, Dong A, Xu X, Brown G, Lu W, Wu H, Cui H, Dombrowski L, Joo JC, Beloglazova N, Min J, Savchenko A, Caudy AA, Rabinowitz JD, Murzin AG, Yakunin AF

Title

Biochemical and structural studies of conserved Maf proteins revealed nucleotide pyrophosphatases with a preference for modified nucleotides.

Journal

Chem Biol 20:1386-98 (2013)
DOI:10.1016/j.chembiol.2013.09.011

Sequence

[hsa:8623]

LinkDB

DBGET integrated database retrieval system