KEGG   ORTHOLOGY: K25517
Entry
K25517                      KO                                     
Symbol
acnX1
Name
mevalonate 5-phosphate dehydratase large subunit [EC:4.2.1.-]
Pathway
map00900  Terpenoid backbone biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00849  C5 isoprenoid biosynthesis, mevalonate pathway, archaea
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    K25517  acnX1; mevalonate 5-phosphate dehydratase large subunit
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.-
     K25517  acnX1; mevalonate 5-phosphate dehydratase large subunit
Other DBs
RN: R12894
COG: COG1679
Genes
STEL: STAQ_21320
CLOS: DMR38_11020
LASA: L9O85_05120
MJA: MJ_1313
MFE: Mefer_1421
MVU: Metvu_1202
MFS: MFS40622_0378
MIF: Metin_0709
MJH: JH146_0315
MESG: MLAUSG7_1120
MMP: MMP1663
MMD: GYY_09170
MMAD: MMJJ_11690
MAE: Maeo_1036
MVO: Mvol_1301
MTH: MTH_1421
METC: MTCT_1292
METE: tca_01372
MST: Msp_0008
MRU: mru_2095
MSI: Msm_1192
MEB: Abm4_0086
MMIL: sm9_0097
MEYE: TL18_10225
MOL: YLM1_1724
METH: MBMB1_2037
MFC: BRM9_0006
MCUB: MCBB_2333
MFV: Mfer_0905
MKA: MK1639
AFU: AF_2333
FPL: Ferp_0108
GAC: GACE_1779
GAH: GAH_00857
PFU: PF0390
PFI: PFC_01030
PHO: PH0354(PH0354)
PAB: PAB1061
PYN: PNA2_0963
PYS: Py04_0662
TKO: TK1249
TON: TON_0514
TGA: TGAM_1120(acnX)
TSI: TSIB_1944
THE: GQS_02585
THA: TAM4_2182
THM: CL1_0165
TLT: OCC_10324
THS: TES1_0899
TNU: BD01_0421
TEU: TEU_08605
PPAC: PAP_03700
MBAR: MSBR2_2053
MBAK: MSBR3_2122
MAC: MA_0245
MMA: MM_1525
MMAC: MSMAC_3162
METM: MSMTP_3040
MTHR: MSTHT_2040
MTHE: MSTHC_1246
MHOR: MSHOH_3879
MBU: Mbur_1472
MMET: MCMEM_1972
MMH: Mmah_1772
MPY: Mpsy_2252
MTP: Mthe_0207
MCJ: MCON_2874
MHI: Mhar_1472
MHU: Mhun_2437
MLA: Mlab_0056
MEMA: MMAB1_1715
MPI: Mpet_1883
MBN: Mboo_0123
MPL: Mpal_0511
MPD: MCP_2308
MEZ: Mtc_1231
RCI: LRC243
HALH: HTSR_1040
HHSR: HSR6_1073
HUT: Huta_0616
HTI: HTIA_0364
MARC: AR505_0453
ABI: Aboo_0849
ACJ: ACAM_1307
SMR: Smar_0622
IHO: Igni_0695
IIS: EYM_07510
DKA: DKAM_0143
TAG: Tagg_1155
IAG: Igag_1938
HBU: Hbut_1634
PAI: PAE2233
PIS: Pisl_0855
PCL: Pcal_0949
PAS: Pars_1920
PYR: P186_0458
POG: Pogu_0207
TNE: Tneu_1398
CMA: Cmaq_0991
TTN: TTX_1590
TUZ: TUZN_1948
VDI: Vdis_1832
VMO: VMUT_0272
TPE: Tpen_0796
ASC: ASAC_0164
ACIA: SE86_01580
NMR: Nmar_0053
NCT: NMSP_0055
NEV: NTE_02684
NCV: NCAV_0094
NBV: T478_0049
NDV: NDEV_0071
CCAI: NAS2_0339
KCR: Kcr_1257
BARC: AOA65_2274
 » show all
Reference
  Authors
Hayakawa H, Motoyama K, Sobue F, Ito T, Kawaide H, Yoshimura T, Hemmi H.
  Title
Modified mevalonate pathway of the archaeon Aeropyrum pernix proceeds via trans-anhydromevalonate 5-phosphate.
  Journal
Proc Natl Acad Sci U S A 115:10034-10039 (2018)
DOI:10.1073/pnas.1809154115
  Sequence
LinkDB

KEGG   ORTHOLOGY: K09128
Entry
K09128                      KO                                     
Symbol
acnX2
Name
mevalonate 5-phosphate dehydratase small subunit [EC:4.2.1.-]
Pathway
map00900  Terpenoid backbone biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00849  C5 isoprenoid biosynthesis, mevalonate pathway, archaea
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    K09128  acnX2; mevalonate 5-phosphate dehydratase small subunit
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.-
     K09128  acnX2; mevalonate 5-phosphate dehydratase small subunit
Other DBs
RN: R12894
COG: COG1786
Genes
RTEA: HK414_17570
DEK: DSLASN_10080
STEL: STAQ_21330
ETM: CE91St48_33550
MJA: MJ_1407
MFE: Mefer_0080
MVU: Metvu_1439
MFS: MFS40622_0336
MIF: Metin_0203
MJH: JH146_0335
MMP: MMP0902
MMD: GYY_05225
MMAD: MMJJ_00900
MAE: Maeo_0452
MVO: Mvol_0933
MTH: MTH_1530
METC: MTCT_1393
METE: tca_01478
MST: Msp_0225
MRU: mru_0202
MSI: Msm_1155
MEB: Abm4_0127
MMIL: sm9_0159
MEYE: TL18_10020
MOL: YLM1_1820
METH: MBMB1_0075
MFC: BRM9_0139
MCUB: MCBB_0100
MFV: Mfer_0495
MKA: MK1486
AFU: AF_0055
FPL: Ferp_0107
GAC: GACE_1778
GAH: GAH_00858
PFU: PF0391
PFI: PFC_01035
PHO: PH0353(PH0353)
PAB: PAB1062
PYN: PNA2_0962
PYS: Py04_0661
TKO: TK1248
TON: TON_0513
TGA: TGAM_1119(acnX)
TSI: TSIB_1943
THE: GQS_02590
THA: TAM4_1938
THM: CL1_0166
TLT: OCC_10319
THS: TES1_0898
TNU: BD01_0420
TEU: TEU_08600
PPAC: PAP_03695
MBAR: MSBR2_2054
MBAK: MSBR3_2123
MAC: MA_0244
MMA: MM_1524
MMAC: MSMAC_3163
METM: MSMTP_3041
MTHR: MSTHT_2041
MTHE: MSTHC_1245
MHOR: MSHOH_3880
MBU: Mbur_1471
MMET: MCMEM_1971
MMH: Mmah_1771
MPY: Mpsy_2251
MTP: Mthe_0208
MCJ: MCON_2875
MHI: Mhar_1471
MHU: Mhun_1041
MLA: Mlab_0800
MEMA: MMAB1_2659
MPI: Mpet_2083
MBN: Mboo_1457
MPL: Mpal_0506
MPD: MCP_2309
MEZ: Mtc_1230
RCI: LRC241
HALH: HTSR_1041
HHSR: HSR6_1074
HUT: Huta_0615
HTI: HTIA_0363
MELU: MTLP_11110
MEAR: Mpt1_c03830(nudI)
MARC: AR505_0454
ABI: Aboo_0848
APE: APE_2089
ACJ: ACAM_1308
SMR: Smar_0623
IHO: Igni_0694
IIS: EYM_07505
DKA: DKAM_0142
TAG: Tagg_1154
IAG: Igag_1937
HBU: Hbut_1633
PAI: PAE2234
PIS: Pisl_0854
PCL: Pcal_0950
PAS: Pars_1919
PYR: P186_0459
POG: Pogu_0208
TNE: Tneu_1399
CMA: Cmaq_1865
TTN: TTX_1589
TUZ: TUZN_1949
VDI: Vdis_2182
VMO: VMUT_0577
TPE: Tpen_0797
ASC: ASAC_0163
ACIA: SE86_01575
NMR: Nmar_0054
NCT: NMSP_0056
NEV: NTE_02685
NCV: NCAV_0093
NBV: T478_0051
NDV: NDEV_0072
CCAI: NAS2_1614
BARC: AOA65_2273
BARB: AOA66_0499
 » show all
Reference
  Authors
Hayakawa H, Motoyama K, Sobue F, Ito T, Kawaide H, Yoshimura T, Hemmi H.
  Title
Modified mevalonate pathway of the archaeon Aeropyrum pernix proceeds via trans-anhydromevalonate 5-phosphate.
  Journal
Proc Natl Acad Sci U S A 115:10034-10039 (2018)
DOI:10.1073/pnas.1809154115
  Sequence
[ape:APE_2089]
LinkDB

KEGG   REACTION: R12894
Entry
R12894                      Reaction                               
Definition
(R)-5-Phosphomevalonate <=> trans-Anhydromevalonate phosphate + H2O
Equation
Comment
mevalonate 5-phosphate dehydratase
Enzyme
4.2.1.-
Pathway
rn00900  Terpenoid backbone biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00849  C5 isoprenoid biosynthesis, mevalonate pathway, archaea
Orthology
K09128  mevalonate 5-phosphate dehydratase small subunit [EC:4.2.1.-]
K25517  mevalonate 5-phosphate dehydratase large subunit [EC:4.2.1.-]
LinkDB

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