KEGG   ORTHOLOGY: K26037
Entry
K26037                      KO                                     
Symbol
CYP76AD1
Name
tyrosine hydroxylase / L-DOPA oxygenase [EC:1.14.-.-]
Pathway
map00950  Isoquinoline alkaloid biosynthesis
map00965  Betalain biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00961  Betacyanin biosynthesis, L-tyrosine => amaranthin
M01072  Mescaline biosynthesis, tyrosine => mescaline
Reaction
R13031  
R13032  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00950 Isoquinoline alkaloid biosynthesis
    K26037  CYP76AD1; tyrosine hydroxylase / L-DOPA oxygenase
   00965 Betalain biosynthesis
    K26037  CYP76AD1; tyrosine hydroxylase / L-DOPA oxygenase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K26037  CYP76AD1; tyrosine hydroxylase / L-DOPA oxygenase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, plant type
  CYP76 family
   K26037  CYP76AD1; tyrosine hydroxylase / L-DOPA oxygenase
Genes
BVG: 104904803(LOC104904803) 104904820(LOC104904820) 104904821(LOC104904821) 104904822(LOC104904822) 104908380(LOC104908380)
SOE: 110779367 110779509 110786794 110786796 110788013 110788024 110792889 110792903
CQI: 110685025 110685039 110699385 110733547 110740013
CALB: 145556763(LOC145556763) 145592601(LOC145592601) 145592603(LOC145592603) 145593160(LOC145593160) 145594909(LOC145594909) 145594935(LOC145594935) 145642451(LOC145642451)
ATRI: 130803140 130806374 130819900 130820538 130820773 130820799
SLAF: 141611400 141613443
AG: AET43289(CYP76AD1) WMX25291(CYP76AD94)
Reference
PMID:22660548
  Authors
Hatlestad GJ, Sunnadeniya RM, Akhavan NA, Gonzalez A, Goldman IL, McGrath JM, Lloyd AM
  Title
The beet R locus encodes a new cytochrome P450 required for red betalain production.
  Journal
Nat Genet 44:816-20 (2012)
DOI:10.1038/ng.2297
  Sequence
[ag:AET43289]
Reference
PMID:34782819
  Authors
Tomizawa E, Ohtomo S, Asai K, Ohta Y, Takiue Y, Hasumi A, Nishihara M, Nakatsuka T
  Title
Additional betalain accumulation by genetic engineering leads to a novel flower color in lisianthus (Eustoma grandiflorum).
  Journal
Plant Biotechnol (Tokyo) 38:323-330 (2021)
DOI:10.5511/plantbiotechnology.21.0516a
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