KEGG ORTHOLOGY: K26130

ORTHOLOGY: K26130

Entry

K26130                      KO

Symbol

SHLD3

Name

shieldin complex subunit 3

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins
    K26130  SHLD3; shieldin complex subunit 3
DNA repair and recombination proteins [BR:ko03400]
Eukaryotic type
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    Other NHEJ factors
     K26130  SHLD3; shieldin complex subunit 3

Genes

HSA:	112441434(SHLD3)

PPS:	117980281(SHLD3)

GGO:	115931265(SHLD3)

NLE:	100601509(SHLD3)

HMH:	116462552(SHLD3)

MCC:

114678803

MCF:	123573969(SHLD3)

MTHB:

126956658

MNI:

105499485

CSAB:

103222379

PANU:

116275026(SHLD3)

TGE:

112626515

MLEU:

105529578

RRO:	104665792(SHLD3)

TFN:	117065195(SHLD3)

PTEH:

113225040(SHLD3)

CANG:

105510789

CJC:	118151685(SHLD3)

SBQ:

101037034

CIMI:

119472594(SHLD3)

MMUR:

105882023

LCAT:

123647957(SHLD3)

PCOQ:

105826538

MMU:	113002583(Shld3)

MCAL:

115029092

RNO:	120101079(Shld3)

MCOC:

116083235(Shld3)

ANU:	117723651(Shld3)

MUN:	132654716(Shld3)

MAUA:

121133122(Shld3)

PLEU:

114703167(Shld3)

MORG:

121455573(Shld3)

MFOT:

126512597

AAMP:

119809512(Shld3)

DSP:	122117151(Shld3)

PLOP:

125367617(Shld3)

NCAR:

124987377

MMMA:

107139445(Shld3)

OCU:

127492811

OPI:	118758215(SHLD3)

TUP:

102475944

GVR:

103586477

CFA:	119870270(SHLD3)

CLUD:

118354000(SHLD3)

VVP:

112935675

VLG:	121497317(SHLD3)

NPO:	129513441(SHLD3)

AML:	117801506(SHLD3)

UMR:	103663630(SHLD3)

UAH:

113255280

UAR:	123790147(SHLD3)

LLV:

125100435

MNP:	132028687(SHLD3)

MLK:	131832295(SHLD3)

NVS:	122919196(SHLD3)

EJU:

114224648

ZCA:	113928711(SHLD3)

MLX:	118016848(SHLD3)

NSU:	110590948(SHLD3)

LWW:	115940667(SHLD3)

FCA:	123386538(SHLD3)

PYU:	121015218(SHLD3)

PBG:	122489505(SHLD3)

PVIV:

125165461(SHLD3)

LRUF:

124517747

PUC:

125935697

AJU:

113594209

HHV:	120247556(SHLD3)

BTA:	132343178(SHLD3)

BBUB:

123330566(SHLD3)

OAS:	114118731(SHLD3)

BTAX:

128065975(SHLD3) 128071312

ODA:	120879590(SHLD3)

CCAD:

122454481(SHLD3)

CFR:	102516108(SHLD3)

CBAI:

105064424

CDK:	105084750(SHLD3)

VPC:	116279401(SHLD3)

BACU:

103014077

BMUS:

118893256(SHLD3)

LVE:

103074416

OOR:	105748059(SHLD3)

DLE:	115801637(SHLD3)

PCAD:

102975410(SHLD3)

PSIU:

116752258(SHLD3)

NASI:

112404909

EPZ:

103553152

EAI:	123286608(SHLD3)

MYB:

106728099

MYD:

102756471

MMYO:

118657011(SHLD3)

MLF:

102432466

PKL:	118702828(SHLD3)

EFUS:

114230135(SHLD3)

SHON:

118998605(SHLD3)

AJM:	119053298(SHLD3)

PDIC:

114491802(SHLD3)

PHAS:

123824844(SHLD3)

MMF:	118641432(SHLD3)

PPAM:

129074583(SHLD3)

RFQ:	117024545(SHLD3)

PGIG:

120608239(SHLD3)

RAY:

107505855

MJV:	118971582(SHLD3)

SARA:

101538988

SETR:

126001526(SHLD3)

LAV:

111749974

TMU:

101352104

GAS:	123232545(SHLD3)

SHR:	116423264(SHLD3)

AFZ:

127558141

PCOC:

116241012(SHLD3)

MGP:	116217525(SHLD3)

CJO:	116652481(SHLD3)

TPAI:

128074533(SHLD3)

LMUT:

125686559(SHLD3)

APLA:

106017265(SHLD3)

ACYG:

125184787(SHLD3)

CATA:

118251459(SHLD3)

AFUL:

116500864(SHLD3)

TGU:	115491223(SHLD3)

LSR:	116184558(SHLD3)

SCAN:

115485082(SHLD3)

PMOA:

120502325(SHLD3)

OTC:	121341245(SHLD3)

PRUF:

121355331(SHLD3)

GFR:

102031415

OMA:	130266813(SHLD3)

PMAJ:

117245587(SHLD3)

CCW:	120411476(SHLD3)

ETL:

114059385

ZAB:

113460018

MMEA:

130588732(SHLD3)

HRT:	120765448(SHLD3)

FPG:

FCH:

CLV:

ACUN:

TALA:

116965505(SHLD3)

ACHC:

115336401(SHLD3)

AGEN:

126036073

GCL:

127027455

SHAB:

115601315(SHLD3)

ACAR:

114818714

RTD:	128902236(SHLD3)

SCAM:

104146884

ASN:

102369172

PSS:

102463139

CMY:	114019325(SHLD3)

DCC:	119855424(SHLD3)

CPIC:

122172316(SHLD3)

TST:	117878864(SHLD3)

CABI:

116820898(SHLD3)

MRV:	120408224(SHLD3)

ACS:

107982361

ASAO:

132767028(SHLD3)

SUND:

121923556(SHLD3)

PGUT:

117679246(SHLD3)

APRI:

131191441(SHLD3)

PTEX:

113447251

NSS:	113430139 113430140 113430141 113430142

VKO:	123031189(SHLD3)

PMUA:

114606502

PRAF:

128423202(SHLD3)

ZVI:	118077270(SHLD3)

STOW:

125436672(SHLD3)

MUO:	115463026(SHLD3)

GSH:	117353802(SHLD3)

DRE:	450064(zgc:101664)

SRX:

SANH:

SGH:

CCAR:

CAUA:

CGIB:

128019078(zgc:101664)

PTET:

122350982(zgc:101664)

LROH:

127169743(zgc:101664)

OMC:	131546375(zgc:101664)

MAMB:

125279364(zgc:101664)

CIDE:

127517391(zgc:101664)

MASI:

127423885

TROS:

130567782(zgc:101664)

MANU:

129414729(zgc:101664)

IPU:	108265953(zgc:101664)

IFU:	128607794(zgc:101664)

PHYP:

113535143

SMEO:

124400507(zgc:101664)

TFD:	113656280(zgc:101664)

TVC:	132853713(zgc:101664)

AMEX:

103035302

CMAO:

118812884(zgc:101664)

EEE:

113570981

CHAR:

105889960(zgc:101664)

TRU:	115247476(shld3)

TFS:	130525970(zgc:101664)

TNG:	GSTEN00034909G001

LCO:

104935223

TBEN:

117472998(zgc:101664)

CGOB:

115012978

PGEO:

117452440(zgc:101664)

GACU:

117535023(zgc:101664)

EMAC:

134872991(zgc:101664)

ELY:	117252230(zgc:101664)

EFO:	125890648(zgc:101664)

PLEP:

121964926

SLUC:

116056641(zgc:101664)

ECRA:

117945282(zgc:101664)

ESP:	116689973(shld3)

PFLV:

114555898

GAT:	120830755(zgc:101664)

PPUG:

119224675(zgc:101664)

AFB:	129101568(zgc:101664)

CLUM:

117736042(zgc:101664)

PSWI:

130196060(zgc:101664)

MSAM:

119891596(zgc:101664)

SCHU:

122876788(zgc:101664)

CUD:	121509247(zgc:101664)

ALAT:

119019186(zgc:101664)

MZE:

101480102

ONL:

100711619

OAU:	116321344(zgc:101664)

OLA:

110015669

OML:	112138445(zgc:101664)

CSAI:

133450873(zgc:101664)

XMA:

102237812

XCO:

114144579

XHE:	116729848(shld3)

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122828564(zgc:101664)

PPRL:

129365687(zgc:101664)

CVG:

107097796

CTUL:

119782414(zgc:101664)

GMU:	124877744(zgc:101664)

NFU:

107386135

KMR:	108245834(zgc:101664)

ALIM:

106527781

NWH:	119413778(zgc:101664)

MCEP:

125012821(zgc:101664)

CSEM:

103398007

POV:

109647847

SSEN:

122769186(zgc:101664)

HHIP:

117768387(zgc:101664)

HSP:	118114740(zgc:101664)

SMAU:

118314220(zgc:101664)

LCF:	108875247(zgc:101664)

SDU:

111236948

SLAL:

111651452

XGL:	120805839(zgc:101664)

HCQ:

109513483

SSCV:

125994195(zgc:101664)

SBIA:

133499257(zgc:101664)

PEE:	133400234(zgc:101664)

PTAO:

133475829(zgc:101664)

BPEC:

110170699

MALB:

109957365

BSPL:

114862289(zgc:101664)

SJO:	128364614(zgc:101664)

STRU:

115167651(shld3)

OTW:	121846369(zgc:101664)

OMY:	110526130(zgc:101664)

OGO:	124033193(zgc:101664)

ONE:	115112008(shld3)

OKI:	109884462(shld3)

OKE:	118393611(zgc:101664)

SALP:

111974932

SNH:	120045067(zgc:101664)

CCLU:

121584090(zgc:101664)

ELS:

105025379

SFM:

108938065

PKI:

111856595

AANG:

118237320(zgc:101664)

LCM:

106703783

CPLA:

122549748(zgc:101664)

HOC:	132819082(zgc:101664)

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

TAD:	TRIADDRAFT_57743

» show all

Reference

PMID:29656893

Authors

Gupta R, Somyajit K, Narita T, Maskey E, Stanlie A, Kremer M, Typas D, Lammers M, Mailand N, Nussenzweig A, Lukas J, Choudhary C

Title

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

Journal

Cell 173:972-988.e23 (2018)
DOI:10.1016/j.cell.2018.03.050

Sequence

[hsa:112441434]

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