KEGG ORTHOLOGY: K26555

ORTHOLOGY: K26555

Entry

K26555                      KO

Symbol

DNHD1

Name

dynein heavy chain domain-containing protein 1

Disease

H01282

Spermatogenic failure

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins
    K26555  DNHD1; dynein heavy chain domain-containing protein 1
Cilium and associated proteins [BR:ko03037]
Motile cilia and associated proteins
  Sperm associated proteins
   K26555  DNHD1; dynein heavy chain domain-containing protein 1

Other DBs

GO:

0051959

Genes

HSA:	144132(DNHD1)

PTR:	748924(DNHD1)

PPS:	100968011(DNHD1)

GGO:	101127440(DNHD1)

PON:	100443908(DNHD1)

NLE:	100600084(DNHD1)

HMH:	116476574(DNHD1)

SSYN:

129484471(DNHD1)

MCC:	712311(DNHD1)

MCF:	102128197(DNHD1)

MTHB:

126935007

MNI:	105488785(DNHD1)

CSAB:

103241319(DNHD1)

CATY:

105575048(DNHD1)

PANU:

101007978(DNHD1)

TGE:	112606150(DNHD1)

MLEU:

105533907(DNHD1)

RRO:	104678301(DNHD1)

RBB:	108543235(DNHD1)

TFN:	117081031(DNHD1)

PTEH:

111524692

CANG:

105520540(DNHD1)

CJC:	100411684(DNHD1)

SBQ:

101036455

CIMI:

108288331(DNHD1)

ANAN:

105720316(DNHD1)

CSYR:

103251427(DNHD1)

MMUR:

105883446(DNHD1)

LCAT:

123642359(DNHD1)

ERUF:

138385201(DNHD1)

PCOQ:

105818386(DNHD1)

OGA:	100948862(DNHD1)

MMU:	77505(Dnhd1)

MCAL:

110298214(Dnhd1)

MPAH:

110322796(Dnhd1)

RNO:	690115(Dnhd1)

MCOC:

116102734(Dnhd1)

ANU:	117698916(Dnhd1)

ASYL:

127663732(Dnhd1)

MUN:	110559578(Dnhd1)

CGE:	100761219(Dnhd1)

MAUA:

101831824(Dnhd1)

PROB:

127228107(Dnhd1)

PLEU:

114683841(Dnhd1)

PMAV:

102911335(Dnhd1)

MORG:

121457538(Dnhd1)

MFOT:

126494109

AAMP:

119817614(Dnhd1)

NGI:	103737593(Dnhd1)

HGL:	101724986(Dnhd1)

CPOC:

100719202(Dnhd1)

CCAN:

109696305(Dnhd1)

DORD:

106000341(Dnhd1)

DSP:	122117639(Dnhd1)

PLOP:

125362404(Dnhd1)

MMMA:

107157723(Dnhd1)

ITI:	101968985(Dnhd1)

OCU:

100337869

OPI:	101529139(DNHD1)

TUP:	102488908(DNHD1)

GVR:

103597706

CFA:	485335(DNHD1)

CLUD:

112667564(DNHD1)

VVP:	112910906(DNHD1)

VLG:	121476091(DNHD1)

NPO:	129504829(DNHD1)

AML:	100480009(DNHD1)

UMR:	103681436(DNHD1)

UAH:	113245860(DNHD1)

UAR:	123782787(DNHD1)

ELK:

111159633

LLV:

125078226

MPUF:

101675420(DNHD1)

MNP:	132012569(DNHD1)

MLK:	131808618(DNHD1)

NVS:	122914248(DNHD1)

ORO:	101366060(DNHD1)

EJU:	114219291(DNHD1)

ZCA:	113914886(DNHD1)

MLX:	118003975(DNHD1)

MANO:

123858039(DNHD1)

NSU:	110576450(DNHD1)

FCA:	101099999(DNHD1)

PYU:	121021120(DNHD1)

PCOO:

112865665(DNHD1)

PBG:	122483495(DNHD1)

PVIV:

125176247(DNHD1)

LRUF:

124505521

LGF:	123601298(DNHD1)

AJU:

106981153

PTG:	102966064(DNHD1)

PPAD:

109271071(DNHD1)

PUC:

125936719

PLEZ:

122200450(DNHD1)

HHV:	120221465(DNHD1)

CCRU:

144227797(DNHD1)

BTA:	617229(DNHD1)

BOM:	102287186(DNHD1)

BIU:	109568855(DNHD1)

BBUB:

102405189(DNHD1)

BKE:	129627756(DNHD1)

BBIS:

104988009(DNHD1)

CHX:	102186033(DNHD1)

OAS:	101110446(DNHD1)

BTAX:

128059839(DNHD1)

CSUM:

138092130(DNHD1)

ODA:	120875879(DNHD1)

CCAD:

122449500(DNHD1)

MREE:

136175895(DNHD1)

MBEZ:

129554584(DNHD1)

SSC:	100518441(DNHD1)

CFR:	102519164(DNHD1)

CBAI:

105076691

CDK:	105097985(DNHD1)

VPC:	102537885(DNHD1)

BACU:

103010845(DNHD1)

BMUS:

118899528(DNHD1)

LVE:	103072312(DNHD1)

OOR:	101282007(DNHD1)

LALB:

132526495(DNHD1)

GMF:	115839518(DNHD1)

DDP:	132430268(DNHD1)

DLE:	111169178(DNHD1)

PCAD:

102977504(DNHD1)

PSIU:

116758609(DNHD1)

PPHC:

136126955(DNHD1)

NASI:

112407684(DNHD1)

ECB:	100070035(DNHD1)

EPZ:	103553535(DNHD1)

EAI:

106838177

MYB:	102256285(DNHD1)

MYD:	102774886(DNHD1)

MMYO:

118665398(DNHD1)

MLF:	102422251(DNHD1)

MDT:	132241891(DNHD1)

MYUM:

139018386(DNHD1)

PKL:	118712970(DNHD1)

EFUS:

103302823(DNHD1)

MNA:	107540480(DNHD1)

DRO:	112312789(DNHD1)

SHON:

118990813(DNHD1)

AJM:	119041141(DNHD1)

PDIC:

114498941(DNHD1)

PHAS:

123819271(DNHD1)

MMF:	118616768(DNHD1)

PPAM:

129076459(DNHD1)

HAI:

109376523

RFQ:	117029691(DNHD1)

PALE:

102881212(DNHD1)

PGIG:

120590226(DNHD1)

PVP:	105309106(DNHD1)

RAY:	107504367(DNHD1)

MJV:	108384230(DNHD1)

TOD:	119255540(DNHD1)

SARA:

101553998(DNHD1)

SFUM:

130025413(DNHD1)

SETR:

126018506(DNHD1)

LAV:	100664186(DNHD1)

TMU:

101347721

ETF:	101648744(DNHD1)

DNM:	101443280(DNHD1)

MDO:	100030927(DNHD1)

GAS:	123241085(DNHD1)

SHR:	100917677(DNHD1)

AFZ:

127557498

PCW:	110200484(DNHD1)

TVP:	118836503(DNHD1)

OAA:	103167328(DNHD1)

TACU:

119942365(DNHD1)

NPD:	112955768(DNHD1)

ASN:

106723078

AMJ:	102560103(DNHD1) 106737442

CPOO:

109305566(DNHD1)

GGN:	109302193(DNHD1)

PSS:

112546998

CMY:	122462520(DNHD1)

NDS:	141998423(DNHD1)

DCC:	119861510(DNHD1)

CPIC:

101953907(DNHD1)

TST:	117882230(DNHD1)

CABI:

116818204(DNHD1) 116826882

MRV:	120400745(DNHD1)

ACS:	103281636(dnhd1)

ASAO:

132770315(DNHD1)

PVT:	110078108(DNHD1)

SUND:

121926882(DNHD1)

PBI:	103059369(DNHD1) 103063936

PMUR:

114922657(DNHD1)

CTIG:

120310038(DNHD1)

TSR:	106541887(DNHD1)

PGUT:

117670861(DNHD1)

PCAE:

139317196(DNHD1)

APRI:

131199214(DNHD1)

PTEX:

113450415(DNHD1)

NSS:	113426071(DNHD1)

VKO:	123022451(DNHD1)

PMUA:

114595134(DNHD1)

PRAF:

128412419(DNHD1)

ZVI:	118085052(DNHD1)

HCG:	128350063(DNHD1)

GJA:	107121990(DNHD1)

STOW:

125431240(DNHD1)

EMC:	129326434(DNHD1)

XLA:

108707607

XTR:	100485299(dnhd1)

NPR:

108801555

RTEM:

120928859(DNHD1)

ACAT:

141126736(DNHD1)

PADS:

140321839(DNHD1)

BBUF:

120996653(DNHD1)

BGAR:

122930526(DNHD1)

DTC:

141078346

GSH:	117362300(DNHD1)

DRE:	110437768(dnhd1)

SRX:

SANH:

SGH:

CCAR:

CAUA:

113055167(dnhd1)

CGIB:

OMC:

PPRM:

RKG:

MAMB:

CIDE:

CERY:

MASI:

TROS:

TDW:

MANU:

129428158(dnhd1)

PDAB:

135719357(dnhd1)

IPU:

108278093

IFU:

128621097

PHYP:

113532491(dnhd1)

SMEO:

TFD:

TVC:

TRN:

AMEX:

CMAO:

EEE:

CHAR:

SPIL:

TRU:	115253247(dnhd1)

TFS:

130526796

LCO:	104925461(dnhd1)

NCC:	104959432(dnhd1)

TBEN:

CGOB:

PGEO:

GACU:

EMAC:

ELY:

EFO:

PLEP:

SLUC:

ECRA:

ESP:

PFLV:

GAT:	120825451 120825452

PPUG:

AFB:

CLUM:

PSWI:

CANA:

CVE:

MSAM:

SCHU:

EARM:

CUD:

SPUL:

LMIX:

HTC:	141805475(dnhd1)

ALAT:

ASTR:

PKLU:

MZE:

ONL:

OAU:

OLA:	101171640(dnhd1)

OML:

CSAI:

XMA:

XCO:

XHE:

PRET:

PFOR:

PLAI:

PMEI:

GAF:

PPRL:

CVG:	107090054(dnhd1)

CTUL:

119796312

GMU:

124868983

NFU:	107375035(dnhd1)

KMR:

NWH:

EJA:

BFRE:

MCEP:

CSEM:

103383233(dnhd1)

POV:	109639249(dnhd1)

SSEN:

SSOE:

HHIP:

HSP:

PPLT:

SMAU:

LCF:

SLAL:

XGL:

HCQ:	109511165(dnhd1)

SSCV:

SBIA:

PEE:

PTAO:

MALB:

BSPL:

SJO:

SSCO:

TTY:

GMH:	115540446(dnhd1)

SASA:

106581207(dnhd1)

STRU:

OTW:

OMY:

OGO:

ONE:	115137768(dnhd1)

OKI:	109904842(dnhd1)

OKE:

OMM:

OCLA:

SFON:

CCLU:

ELS:	105024052(dnhd1)

OEP:

134029391

PKI:	111856811(dnhd1)

AANG:

118209172

AROT:

135235726

CCOG:

133107315

LOC:	102698365(dnhd1)

PSPA:

121327792 121328037

ARUT:

117406109 117406232

LCM:	102365102(DNHD1)

RTP:

109916102

CPLA:

122551092

LERI:

129698445

PMRN:

116948461(DNHD1)

LRJ:	133345202(DNHD1)

BFO:

BBEL:

CIN:

SCLV:

SPU:	100890248 754570

LPIC:

APLC:

ARUN:

AJC:

SKO:

PFLL:

LGI:	LOTGIDRAFT_173233

PCAN:

112564650

LSAX:

138982022

BGT:

106064182

GAE:	121381031 121381492

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

LLON:

NVE:

EPA:

ATEN:

ADF:	107357377 107357380

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HSY:

RES:

TAD:	TRIADDRAFT_54030

» show all

Reference

PMID:34932939

Authors

Tan C, Meng L, Lv M, He X, Sha Y, Tang D, Tan Y, Hu T, He W, Tu C, Nie H, Zhang H, Du J, Lu G, Fan LQ, Cao Y, Lin G, Tan YQ

Title

Bi-allelic variants in DNHD1 cause flagellar axoneme defects and asthenoteratozoospermia in humans and mice.

Journal

Am J Hum Genet 109:157-171 (2022)
DOI:10.1016/j.ajhg.2021.11.022

Sequence

[hsa:144132]

LinkDB

DBGET integrated database retrieval system