KEGG   ORTHOLOGY: K27073
Entry
K27073                      KO                                     
Symbol
hadC
Name
meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadC [EC:4.2.1.-]
Pathway
map00074  Mycolic acid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00886  Meromycolic acid biosynthesis, initiation and elongation FAS II (KasA and KasB)
Reaction
R13272  ultra-long-chain-di-unsaturated-(3R)-3-hydroxyacyl-[acyl-carrier protein] hydro-lyase (ultra-long-chain di-unsaturated trans-2-enoyl-[acyl-carrier protein]-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00074 Mycolic acid biosynthesis
    K27073  hadC; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadC
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins
    K27073  hadC; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadC
Lipid biosynthesis proteins [BR:ko01004]
 Fatty acid synthase
  Component type
   K27073  hadC; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadC
Other DBs
COG: COG2030
Genes
MTU: Rv0637(hadC)
MTV: RVBD_0637
MTC: MT0666
MRA: MRA_0648
MTF: TBFG_10650
MTB: TBMG_00648
MTK: TBSG_00652
MTZ: TBXG_000641
MTG: MRGA327_04000
MTE: CCDC5079_0594
MTUR: CFBS_0669
MTL: CCDC5180_0587
MTO: MTCTRI2_0652
MTD: UDA_0637
MTN: ERDMAN_0705
MTJ: J112_03415
MTUB: MT7199_0655(hadC)
MTUC: J113_04555
MTUE: J114_03410
MTX: M943_03325
MTUH: I917_04555
MTUL: TBHG_00633
MTUT: HKBT1_0669
MTUU: HKBT2_0670
MTQ: HKBS1_0669
MBO: BQ2027_MB0656(hadC)
MBB: BCG_0686
MBT: JTY_0656
MBM: BCGMEX_0657
MBK: K60_006790
MBX: BCGT_0426
MAF: MAF_06460
MMIC: RN08_0712
MCE: MCAN_06361
MCQ: BN44_10699
MCV: BN43_20061
MCX: BN42_20381
MCZ: BN45_10731
MORY: MO_000677(hadC)
MLE: ML1908
MLB: MLBr01908
MPA: MAP_4109
MAO: MAP4_4234
MAVI: RC58_21025
MAVU: RE97_21075
MAV: MAV_4525
MAVM: MAA44156_03967
MIT: OCO_44190
MIA: OCU_43950
MID: MIP_06708
MYO: OEM_44400
MCHI: AN480_23010
MIR: OCQ_45340
MMAL: CKJ54_21035
MLP: MLM_3684
MMAN: MMAN_32390
MSER: MTY59_07540
MSA: Mycsm_00910
MUL: MUL_0722
MMI: MMAR_0970
MMAE: MMARE11_09190
MLI: MULP_01089
MPSE: MPSD_11020
MSHO: MSHO_27490
MMC: Mmcs_0920
MKM: Mkms_0937
MJL: Mjls_0948
MMM: W7S_22260
MKN: MKAN_19345
MYV: G155_06835
MYE: AB431_05140
MHAD: B586_19020
MDX: BTO20_07105
MSHG: MSG_00832
MFJ: MFLOJ_26300
MSTO: MSTO_30110
MSIM: MSIM_16530
MSAK: MSAS_44090
MKU: I2456_04925(hadC)
MLW: MJO58_04435(hadC)
MXE: MYXE_40440
MNV: MNVI_24740
MPAG: C0J29_05310
MNM: MNVM_11710
MGOR: H0P51_04835(hadC)
MCOO: MCOO_41280
MBAI: MB901379_00829
MSEO: MSEO_47810
MHEK: JMUB5695_03949
MGAU: MGALJ_53990
MLJ: MLAC_35410
MBRD: MBRA_06980
MSHJ: MSHI_28040
MMAM: K3U93_04030(hadC)
MSPG: F6B93_04005(hadC)
MOT: LTS72_20810(hadC)
MLM: MLPF_2420
MPAA: MKK62_20385(hadC)
MMEH: M5I08_03280(hadC)
MKY: IWGMT90018_09660
MADI: A7U43_25720
MWU: PT015_22080(hadC)
MYW: BVC93_04795 BVC93_26820
MYJ: BCA37_07215
MHAF: ACEL92_23170(hadC)
MSM: MSMEG_1342
MSG: MSMEI_1304
MSB: LJ00_06690
MSN: LI99_06690
MSH: LI98_06690
MVA: Mvan_1232
MGI: Mflv_5119
MSP: Mspyr1_45370
MCB: Mycch_0878
MNE: D174_06265
MYN: MyAD_06140
MFT: XA26_13650
MPHL: MPHLCCUG_01195
MVQ: MYVA_1041
MLL: B1R94_04870
MRH: MycrhN_0781
MTHN: 4412656_00851
MHAS: MHAS_00158
MDU: MDUV_34740
MCHT: MCHIJ_01640
MDR: MDOR_05180
MAUU: NCTC10437_01014
MMAG: MMAD_10310
MMOR: MMOR_54920
MFX: MFAL_21730
MAIC: MAIC_46630
MIJ: MINS_12810
MALV: MALV_24900
MTY: MTOK_31170
MPSC: MPSYJ_54450
MARZ: MARA_28750
MGAD: MGAD_28910
MHEV: MHEL_12730
MSAR: MSAR_24530
MANY: MANY_48880
MAUB: MAUB_22710
MPOF: MPOR_15080
MPHU: MPHO_47780
MMUC: C1S78_023350(hadC)
MMAT: MMAGJ_41940
MBOK: MBOE_62960
MFG: K6L26_25810(hadC)
MSEI: MSEDJ_23070
MFLV: NCTC10271_04187
MCEE: MCEL_23810
MBRM: L2Z93_003294(hadC)
MMON: EWR22_04970(hadC)
MGO: AFA91_32180
MHOL: K3U96_21965(hadC)
MSEN: K3U95_05920(hadC)
MPAE: K0O64_04720(hadC)
MRF: MJO55_04995(hadC)
MDF: K0O62_05325(hadC)
MCRO: MI149_05375(hadC)
MGRO: FZ046_10995(hadC)
MAUS: JN090_04900(hadC)
MFRE: EXE63_09900(hadC)
MBUG: MU0053_003877(hadC)
MYQ: TUM20985_48200
MFLU: HZU40_09755(hadC)
MYH: QU592_06220(hadC)
MPAT: MPNTM1_00272
MKR: MKOR_23110
MPAK: MIU77_15280(hadC)
MAB: MAB_3896c
MMV: MYCMA_2160
MABB: MASS_3909
MABL: MMASJCM_3913
MCHE: BB28_19980
MIZ: BAB75_22225
MSTE: MSTE_04048
MSAO: MYCSP_18035
MSAL: DSM43276_03692
MJD: JDM601_0660
MTER: 4434518_00646
MMIN: MMIN_23290
MHIB: MHIB_01750
MHER: K3U94_03710(hadC)
MVM: MJO54_03690(hadC)
MKK: MU0083_000613(hadC)
 » show all
Reference
PMID:17804795
  Authors
Sacco E, Covarrubias AS, O'Hare HM, Carroll P, Eynard N, Jones TA, Parish T, Daffe M, Backbro K, Quemard A
  Title
The missing piece of the type II fatty acid synthase system from Mycobacterium tuberculosis.
  Journal
Proc Natl Acad Sci U S A 104:14628-33 (2007)
DOI:10.1073/pnas.0704132104
  Sequence
[mtu:Rv0637]
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