KEGG ORTHOLOGY: K27097

ORTHOLOGY: K27097

Entry

K27097                      KO

Symbol

espR

Name

ESX-1-secreted protein regulator

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K27097  espR; ESX-1-secreted protein regulator
Transcription factors [BR:ko03000]
Prokaryotic type
  Helix-turn-helix
   Other families
    K27097  espR; ESX-1-secreted protein regulator

Genes

MTU:	Rv3849(espR)

MTV:

RVBD_3849

MTC:

MT3964

MRA:

MRA_3889

MTF:	TBFG_13885

MTB:	TBMG_03898

MTK:	TBSG_03922

MTZ:	TBXG_003869

MTI:	MRGA423_24305

MTE:	CCDC5079_3579

MTUR:

CFBS_4082

MTL:	CCDC5180_3527

MTO:	MTCTRI2_3928

MTD:

UDA_3849

MTN:	ERDMAN_4222

MTJ:	J112_20695

MTUB:

MT7199_3918

MTUC:

J113_26915

MTUE:

J114_20575

MTX:	M943_19775

MTUL:

TBHG_03788

MTUT:

HKBT1_4064

MTUU:

HKBT2_4074

MTQ:	HKBS1_4077

MBO:	BQ2027_MB3879(espr)

MBB:

BCG_3912

MBT:

JTY_3914

MBM:	BCGMEX_3914

MBK:	K60_039980

MBX:

BCGT_3720

MAF:

MAF_38640

MMIC:

RN08_4252

MCE:	MCAN_38711

MCQ:	BN44_120275

MCV:	BN43_90378

MCX:	BN42_90382

MCZ:	BN45_110223

MORY:

MO_004006(espR)

MLE:

MLB:

MPA:

MAO:

MAVI:

MAVU:

MAV:

MAVM:

MAA44156_00290(espR)

MIT:

MIA:

MID:

MYO:

MCHI:

MIR:

MMAL:

MLP:

MMAN:

MMAN_16170 MMAN_44350

MSER:

MTY59_04820 MTY59_04830 MTY59_20620 MTY59_39270

MSA:	Mycsm_06225

MUL:

MUL_5021

MMI:

MMAR_5399

MMAE:

MMARE11_52210

MLI:	MULP_05679(espR)

MPSE:

MSHO:

MMC:

MKM:

MJL:

MMM:

MKN:	MKAN_14380

MYV:	G155_28800

MYE:	AB431_28250

MHAD:

B586_02875 B586_05785 B586_10905

MDX:	BTO20_02095 BTO20_19945

MSHG:

MSG_04907

MFJ:	MFLOJ_36100

MSTO:

MSTO_22540 MSTO_40470

MSIM:

MSIM_25590

MSAK:

MSAS_32890 MSAS_40710

MKU:	I2456_27660

MLW:	MJO58_27045

MXE:	MYXE_00680

MNV:	MNVI_16300

MPAG:

C0J29_29835

MNM:	MNVM_20230

MGOR:

H0P51_27640

MCOO:

MCOO_30710

MBAI:

MB901379_04843(espR)

MSEO:

MSEO_38460

MHEK:

JMUB5695_00065

MGAU:

MGALJ_44970

MLJ:	MLAC_43810

MBRD:

MBRA_16600

MSHJ:

MSHI_34480

MMAM:

K3U93_24340

MSPG:

F6B93_18075 F6B93_22110

MOT:	LTS72_25615

MLM:

MLPF_0081

MPAA:

MKK62_00275

MMEH:

M5I08_00365

MKY:	IWGMT90018_61930

MADI:

A7U43_04625

MWU:	PT015_17075

MYW:	BVC93_11285 BVC93_31295 BVC93_31555

MYJ:	BCA37_00565 BCA37_30655 BCA37_30815

MSM:	MSMEG_6431

MSG:	MSMEI_6263

MSB:	LJ00_31790

MSN:	LI99_31795

MSH:	LI98_31800

MVA:

Mvan_5673

MGI:

Mflv_1133

MSP:	Mspyr1_50540

MCB:	Mycch_0719 Mycch_5024

MNE:	D174_00600 D174_10250

MYN:	MyAD_00570 MyAD_10040

MFT:	XA26_58230(espR)

MPHL:

MPHLCCUG_00168(espR_1) MPHLCCUG_01233(espR_3)

MVQ:

MYVA_5602

MLL:	B1R94_27465

MRH:	MycrhN_1906

MTHN:

4412656_04436(espR)

MHAS:

MHAS_04462(espR)

MDU:	MDUV_45500

MCHT:

MCHIJ_16180

MDR:	MDOR_35850

MAUU:

NCTC10437_05439(espR)

MMAG:

MMAD_03830 MMAD_18550 MMAD_52060

MMOR:

MMOR_07410

MFX:	MFAL_27950

MAIC:

MAIC_01780

MIJ:	MINS_04840

MALV:

MALV_38300

MTY:	MTOK_17910

MPSC:

MPSYJ_12060 MPSYJ_21070

MARZ:

MGAD:

MHEV:

MSAR:

MANY:

MAUB:

MAUB_04640 MAUB_30520 MAUB_53070 MAUB_56220

MPOF:

MPOR_02910

MPHU:

MPHO_08010 MPHO_39130 MPHO_56280

MMUC:

C1S78_004905 C1S78_011935 C1S78_014260 C1S78_028215

MMAT:

MMAGJ_27980

MBOK:

MBOE_09520

MFG:	K6L26_02725 K6L26_30860

MSEI:

MSEDJ_06740

MFLV:

NCTC10271_00173(espR)

MCEE:

MCEL_33850

MBRM:

L2Z93_000060

MMON:

EWR22_27225

MGO:	AFA91_04490

MHOL:

K3U96_01450

MSEN:

K3U95_27710

MPAE:

K0O64_28340

MRF:	MJO55_21550 MJO55_26120

MDF:	K0O62_27805

MCRO:

MI149_28165

MGRO:

FZ046_01110 FZ046_04740

MAUS:

JN090_28375

MFRE:

EXE63_00745 EXE63_16505

MBUG:

MU0053_000091

MYQ:	TUM20985_02850

MFLU:

HZU40_01610 HZU40_01980 HZU40_09050

MYH:	QU592_29805

MPAT:

MPNTM1_01575

MKR:	MKOR_13790 MKOR_32590

MPAK:

MIU77_00900

MAB:	MAB_0115c MAB_0495c MAB_1173c MAB_4885

MMV:	MYCMA_0069 MYCMA_0245 MYCMA_07870 MYCMA_11490

MABB:

MASS_0117 MASS_0463 MASS_0810 MASS_1170

MABL:

MMASJCM_0120 MMASJCM_1182 MMASJCM_2875

MCHE:

BB28_00580 BB28_02320 BB28_05780 BB28_08210

MIZ:	BAB75_00875 BAB75_03070 BAB75_06220

MSTE:

MSTE_00114 MSTE_00441 MSTE_01127

MSAO:

MYCSP_00540 MYCSP_02065 MYCSP_05115 MYCSP_13145

MSAL:

DSM43276_00096(espR_1) DSM43276_00405(espR_2) DSM43276_01029(espR_3) DSM43276_02655(espR_4)

MJD:	JDM601_4161

MTER:

4434518_04101(espR)

MMIN:

MMIN_15970

MHIB:

MHIB_34760

MHER:

K3U94_22690

MVM:	MJO54_22755

MKK:	MU0083_003807

ASD:

AS9A_0265

CCN:	H924_13440

CCJZ:

ccrud_14150

NFA:

NFA_5160

NFR:	ERS450000_03715(espR_2)

NCY:	NOCYR_0529

NBR:	O3I_002860 O3I_018725

NNO:	NONO_c05310

NSL:	BOX37_02320 BOX37_28080

NSR:	NS506_01298 NS506_04786

NTP:	CRH09_01350 CRH09_01370 CRH09_03465 CRH09_04520 CRH09_09140 CRH09_24050 CRH09_25725 CRH09_30050 CRH09_38345

NOZ:	DMB37_23760

NOD:	FOH10_28510

NAH:	F5544_02795 F5544_12895

NAD:	NCTC11293_01277(espR)

NWL:	NWFMUON74_05250 NWFMUON74_24880 NWFMUON74_44710

NIE:	KV110_03180

NTC:	KHQ06_03475

NHU:	H0264_04025

NYA:	LTV02_28710

NGP:	LTT66_15675

NSPU:

IFM12276_02090

NYU:	D7D52_04675 D7D52_17355 D7D52_32425

NVU:	V7968_03905 V7968_10275 V7968_22185 V7968_26415 V7968_31935

RHA:	RHA1_ro05642 RHA1_ro08680

RER:

RER_43820

REY:

O5Y_20555

REB:	XU06_20725

RQI:	C1M55_22075 C1M55_31350

ROP:

ROP_57050

ROA:	Pd630_LPD02243

RHB:

NY08_4472

RHW:	BFN03_01640 BFN03_19860

RHQ:	IM25_24675

RHOD:

AOT96_02115

RTM:	G4H71_05080

RKO:	JWS14_30890 JWS14_45710

RGO:	KYT97_29105

ROZ:	CBI38_23080 CBI38_33950

RPSK:

JWS13_13405

RANT:

RHODO2019_17975

RHOO:

RA302_21335 RA302_21630 RA302_23040 RA302_30905 RA302_34050 RA302_34125

RHOJ:

JVH1_08115

RHOH:

CPI83_06705 CPI83_08050 CPI83_08325 CPI83_30245 CPI83_30465

RHOX:

RBB84_12030

RHJS:

OYT95_08410

RHZQ:

GO592_21525 GO592_35935

RHZG:

BO226_25445

RHBH:

A0W34_21015 A0W34_21295 A0W34_22735 A0W34_31220 A0W34_31640

REQ:

REQ_11790

PSOW:

ABI214_07360

WHR:	OG579_11690

GBR:

Gbro_0151

GPO:	GPOL_c03290

GOR:

KTR9_0132

GOQ:	ACH46_18200

GTA:	BCM27_01215

GRU:	GCWB2_00655(espR)

GOM:	D7316_03518(espR)

GAV:	C5O27_03955

GOD:	GKZ92_00990

GOS:	QAD21_01035 QAD21_25170

GOJ:	GR168_01170

GPD:	GII33_22390

GJI:	H1R19_00680

GOI:	LK459_08255

GAMI:

IHQ52_03560

GMG:	NWF22_10655

GOO:	HUN08_00355

SPIN:

KV203_17200

TPR:	Tpau_0121 Tpau_1054 Tpau_1548 Tpau_4027 Tpau_4134

TSM:	ASU32_01265 ASU32_23435

TPUL:

TPB0596_01990 TPB0596_10190 TPB0596_43910 TPB0596_45100

TSD:	MTP03_01100 MTP03_46450(espR)

SRT:

Srot_2459

DCD:	VYL96_17140

TOY:	FO059_18235

SGB:

SFI:

SGRF:

SCYE:

SCB:	SCAB_21711 SCAB_32231

SVL:	Strvi_3257 Strvi_3766 Strvi_9314

SRC:	M271_06630 M271_08925 M271_34550

SMAL:

SMALA_6730 SMALA_7087

SSOI:

I1A49_37420 I1A49_39190

SANT:

QR300_05650 QR300_07600

SBH:	SBI_01035 SBI_01779

SVE:	SVEN_0146 SVEN_0911

SALS:

SLNWT_1203

STRE:

GZL_01954

SLD:	T261_1162 T261_8509

SLC:	SL103_23470

STRM:

M444_05230

SLE:	sle_08170(sle_08170) sle_23340(sle_23340)

SRN:	A4G23_05131(espR)

STRT:

A8713_01070

SCLF:

BB341_30320

SGS:	AVL59_22920

SCAD:

DN051_07345

SNR:	SNOUR_08730

SALU:

DC74_6812

SALL:

SAZ_35380

STRD:

NI25_06470

SAUO:

BV401_37250 BV401_39060

SSIA:

A7J05_08040

SVU:	B1H20_22685 B1H20_30755

SPUN:

BFF78_08075

SGV:	B1H19_34595

SALF:

SMD44_00182 SMD44_04069

SALJ:

SMD11_0314 SMD11_0870 SMD11_6588

SLX:	SLAV_32790(espR1) SLAV_35315(espR2)

STRO:

STRMOE7_32015

SFK:

KY5_0027

SDX:	C4B68_07300

SGD:	ELQ87_00790 ELQ87_25610 ELQ87_38975

SCYA:

EJ357_39515

STIR:

DDW44_30545

SKA:	CP970_02715 CP970_06635

SGZ:	C0216_14295 C0216_19355

SVN:	CP980_08135 CP980_10845 CP980_31390

SHAW:

CEB94_33650

SRK:	FGW37_04225 FGW37_27755

SSPO:

DDQ41_25175

SVR:	CP971_00435

SPAD:

DVK44_17705

SAQU:

EJC51_18105

SGF:	HEP81_01517(espR) HEP81_02030

SSEO:

D0Z67_22510

SRIM:

CP984_03680 CP984_09010 CP984_20545

SSUB:

CP968_32485

SPHV:

F9278_26900

SNF:	JYK04_06301(espR_1) JYK04_07646(espR_2)

SPLA:

CP981_00395 CP981_32600

SCHF:

IPT68_25145

SHUN:

DWB77_07146(espR)

SHAR:

HUT13_23145

SDW:	K7C20_31175

SCAL:

I6J39_30560

SAUH:

SU9_004710 SU9_022185 SU9_027045 SU9_029560

SMOB:

J7W19_02480 J7W19_28870

SPRA:

SPEU:

SANU:

SACT:

SMAO:

SGOB:

test1122_09685 test1122_11515 test1122_22780

SINE:

KI385_33440 KI385_36990

SDEC:

SAOV:

SYAN:

SAKB:

STAA:

SNIG:

SCAE:

IHE65_15105 IHE65_19775

SXT:	KPP03845_100559(espR_1) KPP03845_100785(espR_2)

STUD:

STRTU_000983 STRTU_001898

SENG:

OJ254_27195

SGK:	PET44_03805

SYUN:

MOV08_08620

SOV:	QZH56_03900

SFIY:

F0344_07620 F0344_21290 F0344_24345

SHAU:

K9S39_00610 K9S39_07690 K9S39_10980 K9S39_13595 K9S39_21580

SFP:	QUY26_20835

SCHG:

STTN:

SINN:

STRZ:

SCAY:

SARM:

SLUO:

PS467_04635 PS467_34995

SRPA:

HEP86_00520 HEP86_34025

SMIB:

SMIR_04550

SCAJ:

O1G22_11570 O1G22_40660

STRW:

QHG49_09055

STSD:

HEP87_29790

SGLY:

P8A20_07250 P8A20_30235

SCAT:

STII:

STIC:

SABD:

SPAZ:

STBR:

STVB:

STYI:

C9F11_34920(espR)

SSIR:

WAB15_20095 WAB15_33780

SEXP:

SLV14_001196

SSTO:

ACE1OC_09055 ACE1OC_28495

SLUA:

AB8735_06775 AB8735_31385

STCM:

SCMC78_14210

STID:

G7Z12_05420

SCT:	SCAT_2813 SCAT_3287 SCAT_5001 SCAT_p0262 SCAT_p1288

SCY:	SCATT_27980 SCATT_32840 SCATT_49950 SCATT_p04350 SCATT_p14800

KSK:

KSE_41720

KAB:	B7C62_28905

KIT:	CFP65_0163 CFP65_1890

KIS:	HUT16_19285

KCH:	O1G21_04660 O1G21_37775

KNB:	ACF9IK_18370 ACF9IK_34135

KIC:	KCMC57_up51100

PPOD:

AB0761_02600

YIA:	LO772_29850

STRH:

GXP74_02740 GXP74_22845 GXP74_27900

AREV:

RVR_143 RVR_876

ARX:	ARZXY2_1363

PUE:	FV140_13180

PAYJ:

HMI59_09130

PHRZ:

QN084_01780

PANY:

ACPFL9_09145 ACPFL9_09160

BRX:	BH708_03095

BKI:	M4486_04590

DAY:	FV141_14290

CET:	B8281_13690

CCEU:

CBR64_17930

CPRT:

FIC82_012535

OEK:	FFI11_012830

PSEK:

GCM125_11360

PFR:	PFREUD_22690

PFRE:

RM25_2142

MIK:	FOE78_04990

MICG:

GJV80_18500

AER:	AERYTH_07125

NEX:	NE857_21650

ACIR:

OG979_07215

AWS:	ACN3XK_44900 ACN3XK_45830 ACN3XK_66460

ACTQ:

SRO:

MHAI:

NML:

NAKA:

KRA:

SEN:

SACG:

SVI:	Svir_26750

AMD:	AMED_0904 AMED_1799 AMED_4558 AMED_7104

AMN:	RAM_04610 RAM_09130 RAM_23210 RAM_36455

AMM:	AMES_0901 AMES_1786 AMES_4503 AMES_6996

AMZ:	B737_0902 B737_1787 B737_4503 B737_6996

AOI:	AORI_0901 AORI_1520 AORI_2929 AORI_6078

AJA:	AJAP_09045 AJAP_12330 AJAP_31900 AJAP_35065 AJAP_38685

AMQ:	AMETH_4272

AMYC:

CU254_22115 CU254_26140 CU254_30440 CU254_42200

AMYB:

BKN51_12260 BKN51_23920 BKN51_38615

AAB:	A4R43_10195 A4R43_37995

AMYY:

YIM_11460(espR1) YIM_26330(espR2) YIM_40050(espR3)

AORI:

SD37_22710 SD37_29785 SD37_36745 SD37_39895

APRT:

MUY14_07005 MUY14_14240 MUY14_27490 MUY14_32270

AROO:

NQK81_15260 NQK81_18390 NQK81_22085 NQK81_36290

ATHM:

L1857_24220

ARHD:

VSH64_17215 VSH64_26935 VSH64_42100 VSH64_46950

AMOG:

QRX60_01715 QRX60_06765 QRX60_32805 QRX60_37130

ACOR:

LCL61_00395 LCL61_33000 LCL61_40240

AMYZ:

HUW46_01899 HUW46_02369 HUW46_02800(espR_1) HUW46_03853(espR_2) HUW46_08657

ACAB:

QRX50_03010 QRX50_17855 QRX50_27875 QRX50_47670

ANW:	QP939_01895 QP939_04840 QP939_08040 QP939_11635 QP939_40830

AMYD:

K1T34_07565 K1T34_23060 K1T34_27465 K1T34_50575

AMYE:

MJQ72_25585 MJQ72_29740 MJQ72_33765 MJQ72_37025

AMYS:

CVV72_11285 CVV72_21380 CVV72_24400 CVV72_38915

PDX:	Psed_6070 Psed_6762

PSEH:

XF36_29255

PSEQ:

AD006_15720 AD006_30405

PECQ:

AD017_23560 AD017_30845

PHH:	AFB00_31210 AFB00_31215

PAUT:

Pdca_69330 Pdca_69350

PSDS:

K1T35_47715 K1T35_47865 K1T35_47880

PALQ:

PaSha_28210

KAL:	KALB_1370 KALB_2371 KALB_2580 KALB_374 KALB_637 KALB_8354

KUT:	JJ691_01450(espR_1) JJ691_09440(espR_2) JJ691_35980 JJ691_43660(espR_3) JJ691_51630(espR_4) JJ691_52980

KBR:	Q4V65_08855 Q4V65_11020 Q4V65_12965 Q4V65_16210 Q4V65_22835 Q4V65_25095 Q4V65_40085 Q4V65_43670 Q4V65_45915 Q4V65_47645 Q4V65_53470

KPHY:

AOZ06_09245 AOZ06_23265 AOZ06_38100 AOZ06_40030

LED:	BBK82_46840

LXR:	ACRSBM_02365 ACRSBM_12310 ACRSBM_24310

AHM:	TL08_10710

ACTI:

UA75_11430

ACAD:

UA74_11345

AHG:	AHOG_10670(espR)

ACTA:

C1701_21930

ACAU:

ACOJVX_15835

PMAD:

BAY61_32170

ACTU:

Actkin_03511(espR_1) Actkin_03867(espR_3)

AAUR:

V5P93_003241

CROS:

N8J89_16240 N8J89_28385 N8J89_29530 N8J89_35510 N8J89_38210

UME:	RM788_02930 RM788_33950

STP:	Strop_2282 Strop_4197

SAQ:	Sare_0544 Sare_3100

MTUA:

CSH63_05715

MICH:

FJK98_12085

MSAG:

GCM10017556_27860

VMA:	VAB18032_21945

VER:	HUT12_14310

MENO:

Jiend_54230

MCAY:

PVK37_07100 PVK37_18210 PVK37_19815

MICF:

QQG74_20370

MICN:

WHN02_20610 WHN02_22570 WHN02_22805

VET:	ACQVFL_17760

ASE:

ACPL_3277

ACTS:

ACWT_3149

AIH:	Aiant_71980

ACTR:

Asp14428_40260 Asp14428_77280

ACTL:

L3i22_051070 L3i22_085240

AOU:	ACTOB_002596

ACTE:

ACTI_75890

AFS:

AFR_03400

PLK:	CIK06_27540

PLAB:

PLAT:

PFLA:

PSUU:

PRY:	Prubr_00080

CATI:

CS0771_39440

DVC:	Dvina_40365

DROS:

Drose_22900

DAUR:

Daura_29205 Daura_39355

DMAT:

Dmats_35225

DACT:

KZZ52_19400

CCAZ:

COUCH_36310

CAI:	Caci_3238 Caci_8936

ASLA:

NCTC11923_00393(espR)

ACAP:

MANAM107_09720

ALIL:

D5R93_09775

AEY:	CDG81_02140

JAT:	SAMN05892883_4391

» show all

Reference

PMID:18685700

Authors

Raghavan S, Manzanillo P, Chan K, Dovey C, Cox JS

Title

Secreted transcription factor controls Mycobacterium tuberculosis virulence.

Journal

Nature 454:717-21 (2008)
DOI:10.1038/nature07219

Sequence

[mtu:Rv3849]

Reference

PMID:22479184

Authors

Blasco B, Chen JM, Hartkoorn R, Sala C, Uplekar S, Rougemont J, Pojer F, Cole ST

Title

Virulence regulator EspR of Mycobacterium tuberculosis is a nucleoid-associated protein.

Journal

PLoS Pathog 8:e1002621 (2012)
DOI:10.1371/journal.ppat.1002621

Sequence

[mtu:Rv3849]

LinkDB

DBGET integrated database retrieval system