KEGG Orthology (KO) [BR:ko00001]
09190 Not Included in Pathway or Brite
09193 Unclassified: signaling and cellular processes
99995 Signaling proteins
K27587 JPT, HN; microtubule-associated protein Jupiter
Varisli L, Gonen-Korkmaz C, Debelec-Butuner B, Erbaykent-Tepedelen B, Muhammed HS, Bogurcu N, Saatcioglu F, Korkmaz KS
Title
Ubiquitously expressed hematological and neurological expressed 1 downregulates Akt-mediated GSK3beta signaling, and its knockdown results in deregulated G2/M transition in prostate cells.
Androgen regulated HN1 leads proteosomal degradation of androgen receptor (AR) and negatively influences AR mediated transactivation in prostate cells.