KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09110 Biosynthesis of other secondary metabolites
00999 Biosynthesis of various plant secondary metabolites
K27602 PT4; geranyl-pyrophosphate---olivetolic acid geranyltransferase
Enzymes [BR:ko01000]
2. Transferases
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
2.5.1.102 geranyl-pyrophosphate---olivetolic acid geranyltransferase
K27602 PT4; geranyl-pyrophosphate---olivetolic acid geranyltransferase
Luo X, Reiter MA, d'Espaux L, Wong J, Denby CM, Lechner A, Zhang Y, Grzybowski AT, Harth S, Lin W, Lee H, Yu C, Shin J, Deng K, Benites VT, Wang G, Baidoo EEK, Chen Y, Dev I, Petzold CJ, Keasling JD
Title
Complete biosynthesis of cannabinoids and their unnatural analogues in yeast.
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
Part of the cannabinoids biosynthetic pathway of the plant Cannabis sativa. The enzyme can also use neryl diphosphate as substrate, forming cannabinerolate.
Enzymatic reactions [BR:br08201]
2. Transferase reactions
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
2.5.1.102
R10176 Geranyl diphosphate + 2,4-Dihydroxy-6-pentylbenzoate <=> Diphosphate + Cannabigerolate
