KEGG   ORTHOLOGY: K27778
Entry
K27778                      KO                                     
Symbol
DHVR, RR4
Name
1,2-dihydrovomilenine 19,20-reductase [EC:1.3.1.73]
Pathway
map00901  Indole alkaloid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00979  Ajmaline biosynthesis, geissoschizine => ajmaline
Reaction
R05879  17-O-acetylnorajmaline:NADP+ oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00901 Indole alkaloid biosynthesis
    K27778  DHVR, RR4; 1,2-dihydrovomilenine 19,20-reductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.73  1,2-dihydrovomilenine 19,20-reductase
     K27778  DHVR, RR4; 1,2-dihydrovomilenine 19,20-reductase
Other DBs
GO: 0050615
Genes
AG: ALW82981(VR2) WKU61918(DHVR)
Reference
PMID:38212296
  Authors
Guo J, Gao D, Lian J, Qu Y
  Title
De novo biosynthesis of antiarrhythmic alkaloid ajmaline.
  Journal
Nat Commun 15:457 (2024)
DOI:10.1038/s41467-024-44797-z
  Sequence
[ag:WKU61918 ALW82981]
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