KEGG   ORTHOLOGY: K27792
Entry
K27792                      KO                                     
Symbol
PAS
Name
precondylocarpine acetate synthase [EC:1.21.3.11]
Pathway
map00901  Indole alkaloid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00965  Vinblastine biosynthesis, geissoschizine => vinblastine
Reaction
R13344  stemmadenine acetate:oxygen oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00901 Indole alkaloid biosynthesis
    K27792  PAS; precondylocarpine acetate synthase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.21  Catalysing the reaction X-H + Y-H = X-Y
   1.21.3  With oxygen as acceptor
    1.21.3.11  precondylocarpine acetate synthase
     K27792  PAS; precondylocarpine acetate synthase
Genes
AG: AWJ76616(PAS)
Reference
  Authors
Caputi L, Franke J, Farrow SC, Chung K, Payne RME, Nguyen TD, Dang TT, Soares Teto Carqueijeiro I, Koudounas K, Duge de Bernonville T, Ameyaw B, Jones DM, Vieira IJC, Courdavault V, O'Connor SE
  Title
Missing enzymes in the biosynthesis of the anticancer drug vinblastine in Madagascar periwinkle.
  Journal
Science 360:1235-1239 (2018)
DOI:10.1126/science.aat4100
  Sequence
LinkDB

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