KEGG ORTHOLOGY: K27902

ORTHOLOGY: K27902

Entry

K27902                      KO

Symbol

ACTL9

Name

actin-like protein 9

Disease

H01282

Spermatogenic failure

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins
    K27902  ACTL9; actin-like protein 9
Cilium and associated proteins [BR:ko03037]
Motile cilia and associated proteins
  Sperm associated proteins
   K27902  ACTL9; actin-like protein 9

Other DBs

GO:

0098973

Genes

HSA:	284382(ACTL9)

PTR:	468702(ACTL9)

PPS:	100969933(ACTL9)

GGO:	129528876(ACTL9)

PON:	100441397(ACTL9)

PPYG:

129019277(ACTL9)

NLE:	100607409(ACTL9)

HMH:	116478389(ACTL9)

SSYN:

129460306(ACTL9)

MCC:	708303(ACTL9)

MCF:	102141538(ACTL9)

MTHB:

126942661

MNI:	105481831(ACTL9)

CSAB:

103233845(ACTL9)

CATY:

105593812(ACTL9)

PANU:

100997794(ACTL9)

TGE:	112613104(ACTL9)

MLEU:

105529184(ACTL9)

RRO:	104682277(ACTL9)

RBB:	108534503(ACTL9)

TFN:	117075745(ACTL9)

PTEH:

111530301(ACTL9)

CANG:

105520916(ACTL9)

CJC:	100386032(ACTL9)

SBQ:	101041163(ACTL9)

CIMI:

108283627(ACTL9)

ANAN:

105705917(ACTL9)

CSYR:

103251506(ACTL9)

MMUR:

105885674(ACTL9)

LCAT:

123635723(ACTL9)

PCOQ:

105807880(ACTL9)

OGA:	100944532(ACTL9)

MMU:	69481(Actl9)

MCAL:

110312371(Actl9)

MPAH:

110336144(Actl9)

RNO:	314659(Actl9)

MCOC:

116076297(Actl9)

ANU:	117696847(Actl9)

MUN:	110558112(Actl9)

CGE:	100752462(Actl9)

MAUA:

101844054(Actl9)

PROB:

127217806(Actl9)

PLEU:

114685315(Actl9)

PMAV:

102922302(Actl9)

MORG:

121459200(Actl9)

MFOT:

126494062

AAMP:

119806611(Actl9)

NGI:	103743343(Actl9)

HGL:	101725244(Actl9)

CPOC:

100714799(Actl9)

CCAN:

109684125(Actl9)

DORD:

105992934(Actl9)

DSP:	122111935(Actl9)

DMER:

138810079(Actl9)

PLOP:

125346945(Actl9)

NCAR:

124967847

MMMA:

107157484(Actl9)

ITI:	101964584(Actl9)

OCU:

100353978

OPI:	101516139(ACTL9)

OCZ:	121162938(ACTL9)

TUP:	102501469(ACTL9)

GVR:	103602024(ACTL9)

CFA:	485013(ACTL9)

CLUD:

112666395(ACTL9)

VVP:	112909675(ACTL9)

VLG:	121494566(ACTL9)

NPO:	129522511(ACTL9)

AML:	100475672(ACTL9)

UMR:	103681717(ACTL9)

UAH:	113242687(ACTL9)

UAR:	123777558(ACTL9)

ELK:

111161626

LLV:

125092836

MPUF:

101676971(ACTL9)

MNP:	132009668(ACTL9)

MLK:	131823401(ACTL9)

NVS:	122910795(ACTL9)

ORO:	101376271(ACTL9)

EJU:	114200813(ACTL9)

ZCA:	113917983(ACTL9)

MLX:	118005560(ACTL9)

NSU:	110593988(ACTL9)

LWW:	102748543(ACTL9)

FCA:	101089585(ACTL9)

PYU:	121013846(ACTL9)

PCOO:

112853052(ACTL9)

PBG:	122486354(ACTL9)

PVIV:

125160562(ACTL9)

LRUF:

124523758

LGF:	123607553(ACTL9)

AJU:

113596585

PPAD:

109254228(ACTL9)

PUC:

125928942

PLEZ:

122213282(ACTL9)

HHV:	120244871(ACTL9)

BTA:	540051(ACTL9)

BOM:	102272529(ACTL9)

BIU:	109561206(ACTL9)

BBUB:

102404291(ACTL9)

BBIS:

104979926(ACTL9)

CHX:	102175669(ACTL9)

OAS:	101104573(ACTL9)

BTAX:

128051745(ACTL9)

CSUM:

138085145(ACTL9)

ODA:	120864450(ACTL9)

CCAD:

122439295(ACTL9)

MREE:

136166672(ACTL9)

OVR:	110140286(ACTL9)

MBEZ:

129558022(ACTL9)

SSC:	100736573(ACTL9)

CFR:	102523414(ACTL9)

CBAI:

105078308(ACTL9)

CDK:	105087589(ACTL9)

VPC:	102538355(ACTL9)

BACU:

103004831(ACTL9)

BMUS:

118893541(ACTL9)

LVE:	103073239(ACTL9)

OOR:	101272119(ACTL9)

LALB:

132518699(ACTL9)

GMF:	115865502(ACTL9)

DDP:	132421781(ACTL9)

DLE:	111166113(ACTL9)

PCAD:

102996564(ACTL9)

PSIU:

116752130(ACTL9)

PPHC:

136121389(ACTL9)

NASI:

112400317(ACTL9)

ECB:	100064420 111774306 111774307

EPZ:

EAI:

MYB:

MYD:

MMYO:

118657959(ACTL9)

MLF:

102427312

MDT:	132234206(ACTL9)

MYUM:

139009813(ACTL9)

PKL:	118731169(ACTL9)

EFUS:

103303163(ACTL9)

MNA:	107525722(ACTL9)

DRO:	112312769(ACTL9)

SHON:

118984600(ACTL9)

AJM:	119056012(ACTL9)

PDIC:

114503635(ACTL9)

PHAS:

123814216(ACTL9)

MMF:	118643491(ACTL9)

PPAM:

129061423(ACTL9)

HAI:	109376478(ACTL9)

RFQ:	117037845(ACTL9)

PALE:

102879596(ACTL9)

PGIG:

120599373(ACTL9)

PVP:	105307439(ACTL9)

RAY:	107519894(ACTL9)

MJV:	108401786(ACTL9)

TOD:	119239831(ACTL9)

SARA:

101556625(ACTL9)

SFUM:

130028087(ACTL9)

SETR:

126030097(ACTL9)

TMU:

101350063

ETF:	101656146(ACTL9)

DNM:	101414879(ACTL9)

MDO:	100026731(ACTL9)

GAS:	123232291(ACTL9)

SHR:	100927235(ACTL9)

AFZ:

127543562

PCW:	110202125(ACTL9)

TVP:	118843116(ACTL9)

PBRV:

138177676(ACTL9)

MLAO:

141497664(ACTL9)

GGA:	428337(ACTL9)

PCOC:

116236103

MGP:

104914672

CJO:

107325364

TPAI:

128090410(ACTL9)

LMUT:

125685124(ACTL9)

NMEL:

110389042

APLA:

101802332

ACYG:

106048396(ACTL9)

CATA:

126913582

AFUL:

116499273

GCL:

127025680

MNB:	103769729(ACTL9)

DPUB:

104309493(ACTL9)

PPUS:

135192045(ACTL9)

AVIT:

104272434(ACTL9)

CBOR:

142093690

GSTE:

104260940

AAM:	106486104(ACTL9)

NPD:	112949085(ACTL9)

DNE:	112989586(ACTL9)

ASN:	102378989(ACTL9)

AMJ:	102576457(ACTL9)

CPOO:

109324934(ACTL9)

GGN:	109295045(ACTL9)

PSS:

102449450

CIZ:	142002447(ACTL9)

CMY:	102939732(ACTL9)

CCAY:

125627110(ACTL9)

DCC:	119848434(ACTL9)

CPIC:

101935304(ACTL9)

TST:	117869113(ACTL9)

CABI:

116839632(ACTL9)

MRV:	120391679(ACTL9)

ACS:

100552961

ASAO:

132781483

PVT:	110072613(ACTL9)

SUND:

121937325(ACTL9)

PBI:	103050148 103050398

PMUR:

107282190 107282191

CTIG:

120301351 120301367 120303456 120303463

TSR:

106550827

PGUT:

117677513(ACTL9) 117677516

PCAE:

139308305 139308306

APRI:

131188100

PTEX:

113434970(ACTL9) 113434971

NSS:	113420950 113420951

VKO:	123021462(ACTL9)

PMUA:

114588570(ACTL9)

PRAF:

128405625(ACTL9)

ZVI:	118079241 118086096

HCG:	128330400 128342133

GJA:	107113430(ACTL9)

STOW:

125433269 125433271

EMC:	129329923(ACTL9)

PWL:	138267055 138267984

GSH:

117365485

PSPA:

121300537

ARUT:

117401289 117968487

LCM:	102355443 102355720

CMK:	103183475 103183476

CPLA:

HOC:

LERI:

Reference

PMID:33626338

Authors

Dai J, Zhang T, Guo J, Zhou Q, Gu Y, Zhang J, Hu L, Zong Y, Song J, Zhang S, Dai C, Gong F, Lu G, Zheng W, Lin G

Title

Homozygous pathogenic variants in ACTL9 cause fertilization failure and male infertility in humans and mice.

Journal

Am J Hum Genet 108:469-481 (2021)
DOI:10.1016/j.ajhg.2021.02.004

Sequence

[hsa:284382]

LinkDB

DBGET integrated database retrieval system