KEGG ORTHOLOGY: K28221

ORTHOLOGY: K28221

Entry

K28221                      KO

Symbol

scdC1, fadE33, ipdE2

Name

5OH-HIP-CoA dehydrogenase [EC:1.3.99.-]

Pathway

map00984

Steroid degradation

map01120

Microbial metabolism in diverse environments

Reaction

R13476

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00984 Steroid degradation
    K28221  scdC1, fadE33, ipdE2; 5OH-HIP-CoA dehydrogenase

Other DBs

COG:

COG1960

Genes

RGL:	CS053_01855

PRE:	PCA10_13730

PFUW:

KF707C_12080

PLAL:

FXN65_06375

PPUU:

PputUW4_01650(acdA)

PKC:

PKB_4249

PFZ:	AV641_09530

PLQ:	AA042_00525

PPSY:

AOC04_06355

PSET:

THL1_1424

PSIL:

PMA3_11795

PKE:	DLD99_14795

PUM:	HGP31_21155

PPSH:

G5J76_12640

PAZE:

KSS91_19345

PTAE:

NCTC10697_01823(acdA_1)

PCAV:

D3880_17230

PPHN:

HU825_14680

PIZ:	LAB08_R41060

PSHS:

PSKP:

PDEU:

PBUB:

PSML:

PSMZ:

PKH:	JLK41_05790

SDEG:

HARR:

PPHA:

HASM:

KAK:	Kalk_07770

SPL:

SHL:

COLW:

CBER:

PHA:

PTN:	PTRA_a2584

PNG:	PNIG_a2778

SNAN:

I6N98_06980

ZAL:	AZF00_05320

MSPN:

M8T91_14285

HJA:	BST95_08560

HALC:

EY643_14220

MSEC:

LN244_04965

MRZ:	KDW95_00900

ENW:	MJO57_21335

EMP:	EZMO1_1300

SDF:	ACG33_00360

GPB:	HDN1F_27480

RIN:	ACS15_4376

REH:	H16_B0664(h16_B0664)

CNC:	CNE_2c06110

REU:	Reut_A1568

CTI:	RALTA_B0506

CBW:	RR42_s2326

COX:	E0W60_08265

CUK:	KB879_20765

CUPP:

CTP10_R38950

BUR:	Bcep18194_B1441

BCJ:

BCEN:

BCEO:

BCT:

BCED:

BCEP:

BPYR:

BCON:

BDF:	WI26_21270

BTEI:

BPSL:

BMEC:

BSTL:

BANN:

BARI:

BAEN:

BURK:

BFN:

PBRY:

PPAI:

PVE:	UC34_06985

CABA:

SBC2_48910

CTT:	CtCNB1_1287

CTES:

O987_07340

CRJ:	QMY55_06845

DIH:	G7047_10860

SMIO:

CATMQ487_32060(acd_2)

DOE:	DENOEST_3482

DENI:

B9N43_11360

AZI:	AzCIB_1485

AZD:	CDA09_09850

THU:	AC731_008305

THAU:

C4PIVTH_4180

THAG:

CKCBHOJB_02284

MESS:

ABSY17_13510

AAK:	AA2016_3639

AMIS:

Amn_28070

MTU:	Rv3564(fadE33)

MTV:

RVBD_3564

MTC:

MT3669

MRA:	MRA_3603(fadE33)

MTF:	TBFG_13597

MTB:	TBMG_03603

MTK:	TBSG_03630

MTZ:	TBXG_003578

MTG:	MRGA327_22005

MTI:	MRGA423_22525

MTE:	CCDC5079_3305

MTUR:

CFBS_3780(fadE33)

MTL:	CCDC5180_3257

MTO:	MTCTRI2_3628(fadE33)

MTD:	UDA_3564(fadE33)

MTN:	ERDMAN_3909(fadE33)

MTJ:	J112_19190

MTUB:

MT7199_3626

MTUC:

J113_24960

MTUE:

J114_19060

MTX:	M943_18320

MTUL:

TBHG_03504

MTUT:

HKBT1_3765(fadE33)

MTUU:

HKBT2_3774(fadE33)

MTQ:	HKBS1_3777(fadE33)

MBO:	BQ2027_MB3594(fadE33)

MBB:	BCG_3628(fadE33)

MBT:	JTY_3629(fadE33)

MBM:	BCGMEX_3626(fadE33)

MBK:	K60_037020

MBX:

BCGT_3430

MAF:	MAF_35760(fadE33)

MMIC:

RN08_3941

MCE:	MCAN_35751(fadE33)

MCQ:	BN44_110056(fadE)

MCV:	BN43_90062(fadE)

MCX:	BN42_90061(fadE)

MCZ:	BN45_100063(fadE)

MORY:

MO_003721

MPA:	MAP_0503c(fadE33)

MAO:

MAVI:

MAVU:

MAV:

MAVM:

MAA44156_00516(acdA_3)

MIT:

MIA:

MID:

MYO:

MCHI:

MIR:

MMAL:

MLP:

MMAN:

MMAN_48010(fadE33_2)

MSER:

MTY59_24360(fadE33)

MSA:	Mycsm_05827

MUL:	MUL_4129(fadE33)

MMI:	MMAR_5053(fadE33)

MMAE:

MMARE11_48680(fadE33)

MLI:	MULP_05311(fadE33)

MPSE:

MPSD_52530(fadE33)

MSHO:

MSHO_05350(fadE33)

MMC:

MKM:

MJL:

MMM:

MKN:	MKAN_12055

MYV:	G155_26355

MYE:	AB431_26520

MHAD:

B586_04490

MDX:	BTO20_04525

MSHG:

MSG_04550(fadE33)

MFJ:	MFLOJ_40750(fadE33)

MSTO:

MSTO_44720(fadE33)

MSIM:

MSIM_29170(fadE33)

MSAK:

MSAS_29070(fadE33)

MKU:	I2456_25650

MLW:	MJO58_25050

MXE:	MYXE_05120(fadE33)

MNV:	MNVI_12450(fadE33)

MPAG:

C0J29_27725

MNM:	MNVM_23530(fadE33)

MGOR:

H0P51_25780

MCOO:

MCOO_27220(fadE33)

MBAI:

MB901379_04443

MSEO:

MSEO_34480(fadE33)

MHEK:

JMUB5695_00473(fadE33_1)

MGAU:

MGALJ_38400

MLJ:	MLAC_47400(fadE33)

MBRD:

MBRA_20060(fadE33)

MSHJ:

MSHI_38710(fadE33)

MMAM:

K3U93_22655

MSPG:

F6B93_20460

MOT:	LTS72_27945

MPAA:

MKK62_02435

MKY:	IWGMT90018_57410(fadE33)

MADI:

A7U43_06720

MWU:	PT015_15530

MYJ:	BCA37_02765

MHAF:

ACEL92_03025

MSM:	MSMEG_6016

MSG:	MSMEI_5856(fadE33)

MSB:	LJ00_29745

MSN:	LI99_29750

MSH:	LI98_29755

MVA:

Mvan_5289

MAUS:

JN090_26490

MGI:

Mflv_1477

MSP:	Mspyr1_46900

MCB:	Mycch_4659

MNE:	D174_24640

MYN:	MyAD_24175

MFT:	XA26_53370

MPHL:

MPHLCCUG_00509(acdA_3)

MVQ:	MYVA_5199(fadE33)

MRH:	MycrhN_2262

MTHN:

4412656_04087

MHAS:

MHAS_03768

MDU:	MDUV_49120

MCHT:

MCHIJ_19430(fadE33)

MAUU:

NCTC10437_05047

MMAG:

MMAD_48470

MMOR:

MMOR_11920

MFX:	MFAL_32640(fadE33)

MAIC:

MAIC_05260(fadE33)

MIJ:	MINS_00650

MALV:

MALV_42330

MTY:	MTOK_22100(fadE33)

MPSC:

MPSYJ_15960

MARZ:

MARA_47530

MGAD:

MGAD_37480

MHEV:

MHEL_27710(fadE33)

MSAR:

MSAR_10940(fadE33)

MANY:

MAUB:

MPOF:

MPHU:

MMUC:

MMAT:

MBOK:

MFG:	K6L26_05470

MSEI:

MFLV:

MCEE:

MMON:

MGO:	AFA91_10700

MHOL:

K3U96_03145

MSEN:

K3U95_25385

MPAE:

K0O64_26015

MRF:	MJO55_24080

MDF:	K0O62_25870

MCRO:

MGRO:

MFRE:

MBUG:

MYQ:	TUM20985_06490(fadE33)

MFLU:

HZU40_32960

MYH:	QU592_27345

MPAT:

MPNTM1_01938

MWJ:	ACOI2T_03835

MKR:	MKOR_35440(fadE33)

MPAK:

MIU77_02020

MAB:

MAB_0593c

MMV:	MYCMA_12615

MABB:

MASS_0563

MABL:

MMASJCM_0582

MCHE:

BB28_02830

MIZ:	BAB75_03580

MSTE:

MSTE_00551

MSAO:

MYCSP_02535

MSAL:

DSM43276_00511(acdA_2)

MYY:	RHO23_23795

MJD:	JDM601_3720(fadE33)

MTER:

4434518_03722(fadE33)

MMIN:

MMIN_12440

MHIB:

MHIB_31090(fadE33)

MHER:

K3U94_20985

MVM:	MJO54_20880

MKK:	MU0083_003470

NFA:	NFA_4790(fadE5)

NFR:	ERS450000_03757(caiA_4)

NCY:	NOCYR_0509(fadE)

NBR:	O3I_002755

NNO:	NONO_c05080

NSL:	BOX37_02220

NSR:	NS506_01272

NTP:	CRH09_03365

NOZ:	DMB37_23655

NOD:	FOH10_28645

NAH:	F5544_02690

NAD:	NCTC11293_01253

NWL:	NWFMUON74_05030

NIE:	KV110_03085

NTC:	KHQ06_03600

NHU:	H0264_03895

NYA:	LTV02_28830

NGP:	LTT66_15495

NSPU:

IFM12276_01830

NYU:	D7D52_04560

NVU:	V7968_10175

RHA:	RHA1_ro04591

RER:

RER_08860

REY:

O5Y_03920

REB:	XU06_04160

RQI:	C1M55_04390

ROP:

ROP_45360

ROA:	Pd630_LPD01068

RPY:	Y013_19110

RBY:	CEJ39_05475

RAV:	AAT18_04005

RHW:	BFN03_15080

RRZ:	CS378_19650

RHQ:	IM25_08960

RHOD:

AOT96_14790

RRT:	4535765_00598(caiA_1)

RCR:	NCTC10994_02122

RTM:	G4H71_07315

RKO:	JWS14_25285

RGO:	KYT97_23435

ROZ:	CBI38_04285

RPSK:

RGOR:

RHOP:

RHOO:

RHOU:

RHOW:

RHOJ:

RHOS:

RHOQ:

RHOY:

RHOH:

RHOX:

RHJS:

RSF:	OED52_02370

RHZQ:

RHZG:

RHBH:

RHPD:

RHON:

RHWB:

RHPM:

RHPC:

RHSQ:

RHWY:

GFS60_00892(fadE)

RHDM:

RHWQ:

RHMM:

RHZP:

RHRC:

RHNY:

RHRD:

RHDK:

RHMZ:

RIO:	ACM26Y_03545

RHDE:

PSR88_23350

REQ:

REQ_06980

PSOW:

ABI214_10150

WHR:	OG579_17670

GBR:

Gbro_0926

GPO:	GPOL_c40970

GOR:	KTR9_0827(fadE33)

GOQ:	ACH46_03320

GTA:	BCM27_05145

GOC:	CXX93_06510

GIT:	C6V83_04310

GRU:	GCWB2_04210(acdA4)

GOM:	D7316_02448

GAV:	C5O27_00825

GOD:	GKZ92_04005

GOS:	QAD21_04160

GOJ:	GR168_04285

GAM:	GII34_18755

GPD:	GII33_03980

GJI:	H1R19_04085

GOI:	LK459_05050

GAMI:

IHQ52_06865

GMG:	NWF22_15825

GSI:	P5P27_15745

GOO:	HUN08_03025

GOP:	ACE11G_03200

SPIN:

KV203_17330

TPR:

Tpau_3840

TSM:	ASU32_21875

TPUL:

TPB0596_41800

DTM:	BJL86_0710

DIT:	C3V38_09295

DIZ:	CT688_03215

DPC:	A6048_03160

DLU:	A6035_03455

DKN:	NHB83_03010

DCD:	VYL96_03240

DID:	GJR88_01040

TOY:	FO059_13915

MRN:	K8F61_15915

MSUF:

KV394_02700

MWN:	QNO26_01545

MICJ:

LRQ07_15400

ARL:	AFL94_16440

ARY:	ATC04_01430

ASUN:

KG104_08945

ARTA:

OL239_10540

GPR:	JQN66_16755

PAEY:

KUF55_17835

NCA:

Noca_2771

NDK:	I601_0623(mmgC_7)

NBE:	Back2_27260

NANO:

G5V58_09805

NARO:

CFH99_13500

NPI:	G7071_15920

NPC:	KUV85_04300

NMAR:

HPC71_09565

NFC:	KG111_08335

NBI:	SHK19_12450

NOF:	MF408_21055

NOCR:

NOCW:

NOCD:

NOCQ:

PSIM:

AEB:	C6I20_03305

AMD:

AMN:

AMM:

AMZ:

AOI:

AJA:	AJAP_26350

AMQ:	AMETH_4455(acd)

AMYC:

CU254_23965

AMYB:

BKN51_05085

AMYY:

YIM_33150(mmgC17)

AORI:

AACD:

APRT:

AROO:

ATHM:

ARHD:

AMOG:

ACYN:

ACOR:

AMYZ:

ANW:	QP939_43960

AMYD:

ABAR:

AMYE:

AMYS:

KAL:

LED:	BBK82_38895

ALO:

CRK57778

STP:	Strop_2619

SAQ:

Sare_2818

JAT:	SAMN05892883_1542

» show all

Reference

PMID:12676694

Authors

Horinouchi M, Hayashi T, Koshino H, Yamamoto T, Kudo T

Title

Gene encoding the hydrolase for the product of the meta-cleavage reaction in testosterone degradation by Comamonas testosteroni.

Journal

Appl Environ Microbiol 69:2139-52 (2003)
DOI:10.1128/AEM.69.4.2139-2152.2003

Sequence

[ctt:CtCNB1_1287]

Reference

PMID:31375491

Authors

Horinouchi M, Koshino H, Malon M, Hirota H, Hayashi T.

Title

Steroid Degradation in Comamonas testosteroni TA441: Identification of the Entire beta-Oxidation Cycle of the Cleaved B Ring.

Journal

Appl Environ Microbiol 85:e01204-19 (2019)
DOI:10.1128/AEM.01204-19

Reference

PMID:32101684

Authors

Gadbery JE, Round JW, Yuan T, Wipperman MF, Story KT, Crowe AM, Casabon I, Liu J, Yang X, Eltis LD, Sampson NS

Title

IpdE1-IpdE2 Is a Heterotetrameric Acyl Coenzyme A Dehydrogenase That Is Widely Distributed in Steroid-Degrading Bacteria.

Journal

Biochemistry 59:1113-1123 (2020)
DOI:10.1021/acs.biochem.0c00005

Sequence

[mtu:Rv3564]

LinkDB

DBGET integrated database retrieval system