KEGG ORTHOLOGY: K28229

ORTHOLOGY: K28229

Entry

K28229                      KO

Symbol

scdL2, ipdB

Name

COCHEA-CoA hydrolase beta subunit [EC:4.1.-.-]

Pathway

map00984

Steroid degradation

Reaction

R13482

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00984 Steroid degradation
    K28229  scdL2, ipdB; COCHEA-CoA hydrolase beta subunit

Other DBs

COG:

COG2057

Genes

RGL:	CS053_01810

VAF:	D1115_22670

PRE:	PCA10_13400

PFUW:

PLAL:

PPUT:

PPUN:

PPUU:

PKC:

PFZ:	AV641_10725

PLQ:	AA042_19970

PPSY:

AOC04_08030

PSET:

THL1_1412

PSIL:

PMA3_11810

PKE:	DLD99_14635

PUM:	HGP31_20690

PPSH:

G5J76_13980

PAZE:

KSS91_19150

PTAE:

NCTC10697_02094(catJ)

PCAV:

D3880_17215

PPHN:

HU825_14500

PIZ:	LAB08_R40710

PKM:	PZ739_11720

PSHS:

PLAU:

PFOU:

PSKP:

PDEU:

PBUB:

PSML:

PSMZ:

PSWO:

PMOR:

PKH:	JLK41_05805

SDEG:

HARR:

PPHA:

HASM:

KAK:	Kalk_07815

SPL:

SHL:

COLW:

CBER:

PHA:

PTN:	PTRA_a1034(gctB)

PNG:	PNIG_a1086(gctB)

SNAN:

I6N98_06940

ZAL:	AZF00_05280

MSPN:

M8T91_14325

HJA:	BST95_08525

HALC:

EY643_14255

KIM:	G3T16_13750

AFUS:

EYZ66_12935

PAQM:

E0F26_07505

MSEC:

LN244_05130

MRZ:	KDW95_01135

ENW:	MJO57_22790

EMP:	EZMO1_1287(atoA)

SDF:	ACG33_00315

SOK:	D0B54_05290

SINI:

GT972_08450

FCE:	JN531_005440

GPB:	HDN1F_27390(tesB)

RIN:	ACS15_4382

REH:	H16_B0656(h16_B0656)

CNC:	CNE_2c06030

CUH:	BJN34_30705

REU:	Reut_A1559

CTI:	RALTA_B0498(gctB)

CBW:	RR42_s2334

COX:	E0W60_08225

CUK:	KB879_20725

CUPP:

CTP10_R38870

BUR:	Bcep18194_B1433

BCJ:

BCEN:

BCEO:

BCT:

BCED:

BCEP:

BPYR:

BCON:

BDF:	WI26_21310

BTEI:

BPSL:

BMEC:

BSTL:

BANN:

BARI:

BAEN:

BURK:

BFN:

PBRY:

PPAI:

PVE:	UC34_06945

CABA:

SBC2_48830

CTT:	CtCNB1_1277

CTES:

O987_07295

CRJ:	QMY55_06805

DIH:	G7047_10905

SMIO:

CATMQ487_32150

DOE:	DENOEST_1367

DENI:

B9N43_04460

AZD:	CDA09_09630

THU:	AC731_008505

THAU:

C4PIVTH_4230

THAG:

CKCBHOJB_02320

MESS:

ABSY17_13445

AAK:	AA2016_3652

AMIS:

Amn_27940

GYJ:	AADW23_16445

FRB:	AB6B37_08160

NAR:

Saro_3752

NPP:	PP1Y_Mpl3047

NOV:	TQ38_027265

NOT:	C7W88_20760

NOR:	FA702_21050

NOVO:

IM701_18095 IM701_20470

SPOG:

SWI:

SPHD:

SPHM:

SPHI:

SSAN:

SPKC:

SPHA:

SLAN:

SBIN:

SPCL:

SPHB:

EP837_03388(gctB)

SPCA:

GL174_15740

PHAO:

HF685_05550

CNA:	AB433_04800

PHZ:	CHX26_05285

NTD:	EGO55_13710

CAEN:

K5X80_14705

HFO:	ABFZ83_09715

MTU:

MTV:

MTC:

MRA:

MTF:	TBFG_13585

MTB:	TBMG_03591

MTK:	TBSG_03618

MTZ:	TBXG_003567

MTG:	MRGA327_21930

MTI:	MRGA423_22450

MTE:	CCDC5079_3293

MTUR:

CFBS_3768

MTL:	CCDC5180_3245

MTO:	MTCTRI2_3616

MTD:

UDA_3552

MTN:	ERDMAN_3897

MTJ:	J112_19120

MTUB:

MT7199_3614

MTUC:

J113_24840

MTUE:

J114_18995

MTX:	M943_18260

MTUH:

MTUL:

MTUT:

MTUU:

MTQ:	HKBS1_3765

MBO:	BQ2027_MB3582

MBB:

BCG_3616

MBT:

JTY_3617

MBM:	BCGMEX_3614

MBK:	K60_036900

MBX:

BCGT_3418

MAF:

MAF_35640

MMIC:

RN08_3928

MCE:	MCAN_35631

MCQ:	BN44_110044

MCV:	BN43_90050

MCX:	BN42_90047

MCZ:	BN45_100047

MORY:

MPA:

MAO:

MAVI:

MAVU:

MAV:

MAVM:

MAA44156_00527(catJ)

MIT:

MIA:

MID:

MYO:

MCHI:

MIR:

MMAL:

MLP:

MMAN:

MSER:

MSA:	Mycsm_05817

MUL:

MUL_4115

MMI:

MMAR_5041

MMAE:

MMARE11_48510

MLI:	MULP_05294

MPSE:

MSHO:

MMC:

MKM:

MJL:

MMM:

MKN:	MKAN_11945

MYV:	G155_26230

MYE:	AB431_26460

MHAD:

B586_04540

MDX:	BTO20_31455

MSHG:

MSG_04539

MFJ:	MFLOJ_40840

MSTO:

MSTO_44810

MSIM:

MSIM_29260

MSAK:

MSAS_28960

MKU:	I2456_25595

MLW:	MJO58_25000

MXE:	MYXE_05970

MNV:	MNVI_12360

MPAG:

C0J29_27640

MNM:	MNVM_23670

MGOR:

H0P51_25720

MCOO:

MCOO_27070

MBAI:

MB901379_04431(catJ)

MSEO:

MSEO_34340

MHEK:

JMUB5695_00495

MGAU:

MGALJ_38280

MLJ:	MLAC_47550

MBRD:

MSHJ:

MMAM:

MSPG:

MOT:	LTS72_28015

MPAA:

MKK62_02505

MKY:	IWGMT90018_57270

MADI:

A7U43_06840

MWU:	PT015_15465

MYW:	BVC93_09185

MYJ:	BCA37_02820

MSM:	MSMEG_6003

MSG:	MSMEI_5842

MSB:	LJ00_29680

MSN:	LI99_29685

MSH:	LI98_29690

MVA:

Mvan_5268

MGI:

Mflv_1488

MSP:	Mspyr1_46790

MCB:	Mycch_4646

MNE:	D174_24550

MYN:	MyAD_24085

MFT:	XA26_53160

MPHL:

MPHLCCUG_00524(catJ)

MVQ:

MYVA_5182

MLL:	B1R94_25300

MRH:	MycrhN_2277

MTHN:

4412656_04070(gctB)

MHAS:

MHAS_03748

MDU:	MDUV_49290

MCHT:

MCHIJ_19600

MAUU:

NCTC10437_05022(catJ)

MMAG:

MMAD_48360

MMOR:

MMOR_12100

MFX:	MFAL_32900

MAIC:

MAIC_05390

MIJ:	MINS_00380

MALV:

MALV_42490

MTY:	MTOK_22220

MPSC:

MARZ:

MGAD:

MHEV:

MSAR:

MANY:

MAUB:

MPOF:

MPHU:

MMUC:

MMAT:

MBOK:

MFG:	K6L26_05560

MSEI:

MSEDJ_02260

MFLV:

NCTC10271_00490(catJ)

MCEE:

MCEL_38020

MMON:

EWR22_25350

MGO:	AFA91_10775

MHOL:

K3U96_03200

MSEN:

K3U95_25275

MPAE:

K0O64_25955

MRF:	MJO55_24015

MDF:	K0O62_25805

MCRO:

MGRO:

MAUS:

MFRE:

MBUG:

MYQ:	TUM20985_06640

MFLU:

HZU40_32895

MKR:	MKOR_35580

MPAK:

MIU77_02090

MAB:

MAB_0604c

MMV:	MYCMA_0311

MABB:

MASS_0574

MABL:

MMASJCM_0593

MCHE:

BB28_02890

MIZ:	BAB75_03640

MSTE:

MSTE_00563

MSAO:

MYCSP_02590

MSAL:

DSM43276_00522(catJ)

MJD:	JDM601_3706

MTER:

4434518_03706(catJ)

MMIN:

MMIN_12300

MHIB:

MHIB_30970

MHER:

K3U94_20910

MVM:	MJO54_20810

MKK:	MU0083_003453

ASD:

AS9A_0956

NFA:

NFA_5080

NFR:	ERS450000_03724(catJ_2)

NCY:	NOCYR_0521

NBR:	O3I_002820

NNO:	NONO_c05230

NSL:	BOX37_02280

NSR:	NS506_01288(gctB)

NTP:	CRH09_03425

NOZ:	DMB37_23720

NOD:	FOH10_28550

NAH:	F5544_02755

NAD:	NCTC11293_01269(catJ)

NWL:	NWFMUON74_05170

NIE:	KV110_03140

NTC:	KHQ06_03500

NHU:	H0264_03985

NYA:	LTV02_28755

NGP:	LTT66_15635

NSPU:

IFM12276_02010

NYU:	D7D52_04635

NVU:	V7968_10235

RHA:	RHA1_ro04650

RER:

RER_09180

REY:

O5Y_04085

REB:	XU06_04330

RQI:	C1M55_04565 C1M55_18945

ROP:

ROP_47480

ROA:	Pd630_LPD01152

RPY:	Y013_19195

RBY:	CEJ39_05560

RAV:	AAT18_04095

RHW:	BFN03_14790

RRZ:	CS378_19730

RHOD:

AOT96_14970 AOT96_29575

RRT:	4535765_00615(catJ_1)

RCR:	NCTC10994_02106(catJ)

RTM:	G4H71_07220

RKO:	JWS14_25645

RGO:	KYT97_14660

ROZ:	CBI38_04815

RPSK:

JWS13_18745

RGOR:

NMQ04_02680

RHOP:

D8W71_08030

RHOO:

RA302_04435 RA302_18445

RHOU:

KZJ41_04090

RHOW:

A4U64_20680

RHOJ:

JVH1_13000(ipdB)

RHOS:

RHOQ:

RHOY:

RHOH:

RHOX:

RHJS:

RSF:	OED52_02440

RHZQ:

GO592_26310

RHZG:

BO226_23610

RHBH:

A0W34_04375

RHPD:

U9J23_02875(ipdB)

REQ:	REQ_00860 REQ_07160

PDEF:

P9209_03040

PSOW:

ABI214_10060 ABI214_13585

WHR:	OG579_09385

GBR:

Gbro_3983

GPO:	GPOL_c43050

GOR:	KTR9_3915(ipdB)

GOQ:	ACH46_17565

GTA:	BCM27_20520

GOC:	CXX93_00600

GIT:	C6V83_03865

GRU:	GCWB2_20015(catJ)

GOM:	D7316_04500

GAV:	C5O27_08100

GOD:	GKZ92_18940

GOJ:	GR168_18770

GAM:	GII34_18920

GPD:	GII33_03825

GJI:	H1R19_18870

GOI:	LK459_13740

GHN:	MVF96_19455

GAMI:

IHQ52_22995

GMG:	NWF22_06435

GSI:	P5P27_01130

GOO:	HUN08_15910

GOP:	ACE11G_15675

SPIN:

KV203_17235

TPR:

Tpau_3828

TSM:	ASU32_21815

TPUL:

TPB0596_41690

TSD:	MTP03_43120

DTM:	BJL86_0728

DIT:	C3V38_09365

DIZ:	CT688_03285

DPC:	A6048_03235

DLU:	A6035_03525

DKN:	NHB83_03095

DCD:	VYL96_03310

TOY:	FO059_13865

SMA:	SAVERM_6201(cotB)

SGR:

SGB:

SFI:

SANL:

SGRF:

SCYE:

SCB:	SCAB_68711

SVL:	Strvi_4080

SRC:	M271_04990 M271_44245

SMAL:

SSOI:

SBH:

SVE:

SDV:	BN159_6436

SCI:	B446_10575

SVT:	SVTN_35830

STRE:

GZL_01199

SLD:

T261_0444

SLC:	SL103_15020

STRM:

M444_10250

SPRI:

SPRI_5497

SCZ:	ABE83_27940

SCX:	AS200_32870

SRW:	TUE45_02543(catJ)

SCLF:

BB341_21985

SGS:	AVL59_37055

STSI:

A4E84_00875

SALW:

CP975_30875

SGM:	GCM10017557_61960

SCAD:

DN051_28320

SPHW:

NFX46_30865

SLS:	SLINC_2345

SNR:	SNOUR_05110

SALU:

SALL:

SPLU:

SAUO:

SSIA:

SVU:	B1H20_06945

SPUN:

BFF78_01780

SGV:	B1H19_37140

SLAU:

SLA_1557

SALF:

SMD44_07226

SALJ:

SMD11_0774

SLX:	SLAV_27315(catJ)

STRO:

STRMOE7_04810

SFK:

KY5_7032c

SNZ:	DC008_08450

SGE:	DWG14_08123

SRJ:

SRO_5451

SLK:	SLUN_09835

SDX:	C4B68_30130

SGD:	ELQ87_29245

SQZ:	FQU76_06675

SCYA:

EJ357_11865

STIR:

DDW44_03315

SKA:	CP970_04900

SGZ:	C0216_23135

SVN:	CP980_24855

SNK:	CP967_03035

SHAW:

CEB94_10925

SRK:	FGW37_28060

SFIC:

EIZ62_25060

SGAL:

CP966_08915

SSPO:

DDQ41_02685

SFY:	GFH48_29880

SAQU:

EJC51_13635

SGF:	HEP81_05758

SCAV:

SRIM:

SSUB:

SPHV:

STSU:

SCHA:

SGX:	H4W23_38465

SCOE:

CP976_11700

SSPB:

CP982_33805

SNF:	JYK04_02669

SPLA:

SBRO:

STUI:

SATA:

SHUN:

SCYG:

S1361_11135(catJ)

SFEU:

IM697_11835

SDW:	K7C20_03225

SCAL:

SAUH:

SPEU:

SROI:

SXN:	IAG42_26695

SHK:	J2N69_32370

SANU:

STRY:

SGOB:

SINE:

SLF:	JEQ17_34415

SDEC:

SAOV:

SDUR:

SYAN:

SRUG:

SAKB:

STAA:

SNIG:

SCAE:

STUB:

SSPN:

SCIR:

SXT:	KPP03845_102236

SLON:

LGI35_13910

STUD:

STRTU_006620

SGK:	PET44_08870

SANT:

QR300_02015

SYUN:

MOV08_04845

SJN:	RI060_31905

SCYN:

N8I84_11280

SOV:	QZH56_03650

SFIY:

F0344_28340

SHAU:

K9S39_08210

SKG:	KJK29_28855

SCOA:

QU709_32730

SLAI:

P8A22_33575

SFP:	QUY26_06110

STTN:

BSL84_08710

SINN:

ABB07_34050

KBU:	Q4V64_12690

SLUO:

STPB:

SRPA:

SMIB:

SCAJ:

STRW:

STRL:

STSD:

SRPZ:

SCHE:

SCAT:

STII:

STIC:

SABD:

SPAZ:

SMOD:

SPOF:

STBR:

STAC:

STVB:

SSOC:

SSLI:

STYI:

C9F11_32940(catJ)

SCT:

SCAT_5624

SCY:	SCATT_56220

KAB:	B7C62_06830

YIA:	LO772_20230

STRH:

GXP74_18325

AGLA:

OIE69_15350

MRN:	K8F61_15885 K8F61_15955

MSUF:

KV394_02660 KV394_02740

ARL:	AFL94_16380 AFL94_16460

ARY:	ATC04_01410 ATC04_01485

ASUN:

KG104_08925 KG104_08990

ARTA:

OL239_10495 OL239_10550

GPR:	JQN66_16695 JQN66_16775

PAEY:

KUF55_17790 KUF55_17850

NCA:

Noca_2745

NDK:	I601_0612(catJ)

NBE:	Back2_27590

NANO:

G5V58_09880

NARO:

CFH99_13425

NPI:	G7071_15855

NPC:	KUV85_04355

NMAR:

HPC71_09620

NFC:	KG111_08420

NBI:	SHK19_12370

NOCR:

OSR43_09665

NOCW:

ABFU82_07440 ABFU82_23105

NOCA:

ncot_09635

NOCL:

KM427_12650

NOCD:

QJ852_14405

NOCQ:

QI633_11990 QI633_24875

PSIM:

KR76_14370 KR76_25110

AEB:	C6I20_03375

NGV:	CDO52_10830

TCU:

ACTW:

AMAZ:

ACIR:

AWS:	ACN3XK_35770 ACN3XK_36390

SPIQ:

OHA34_37845

ACTQ:

OG417_40405

SRO:

Sros_2063

NOA:	BKM31_34345

NCX:	Nocox_09765(catJ)

NGN:	LCN96_11025

NFS:	OIE67_36005

FRI:	FraEuI1c_1921

AMD:

AMN:

AMM:

AMZ:

AOI:

AJA:	AJAP_26230

AMQ:	AMETH_4464(catJ)

AMYC:

CU254_23980

AMYB:

BKN51_05205

AAB:	A4R43_15960

AMYY:

YIM_33200(catJ3)

AORI:

AACD:

APRT:

AROO:

ATHM:

ARHD:

AMOG:

ACYN:

ACOR:

AMYZ:

ANW:	QP939_44010

AMYD:

ABAR:

AMYE:

AMYS:

PSDS:

KAL:

KUT:	JJ691_41380

KBR:	Q4V65_07755

KPHY:

AOZ06_42555

LED:	BBK82_38845

ALO:

PMAD:

SACE:

CROS:

STP:	Strop_2606

SAQ:

Sare_2805

MICB:

MicB006_5694

MCHL:

PVK74_03240

AMS:	AMIS_21680

AIH:	Aiant_18410

ACTL:

L3i22_084040

ASIC:

Q0Z83_065040

AOU:	ACTOB_004184

ACTE:

ACTI_41580

DVC:	Dvina_21495

DFU:	Dfulv_25850

DROS:

DAUR:

DMAT:

DACT:

CAI:

JCY:	M6B22_17370

ABAI:

IMCC26256_111850

CWO:

Cwoe_2355

AQZ:	KSP35_09510

IAM:	HC251_18140

IMA:	PO878_16975

DHI:	LH044_15605

LEPV:

J4558_08960

» show all

Reference

PMID:12676694

Authors

Horinouchi M, Hayashi T, Koshino H, Yamamoto T, Kudo T

Title

Gene encoding the hydrolase for the product of the meta-cleavage reaction in testosterone degradation by Comamonas testosteroni.

Journal

Appl Environ Microbiol 69:2139-52 (2003)
DOI:10.1128/AEM.69.4.2139-2152.2003

Sequence

[ctt:CtCNB1_1277]

Reference

PMID:30194104

Authors

Horinouchi M, Koshino H, Malon M, Hirota H, Hayashi T.

Title

Steroid Degradation in Comamonas testosteroni TA441: Identification of Metabolites and the Genes Involved in the Reactions Necessary before D-Ring Cleavage.

Journal

Appl Environ Microbiol 84 (2018)
DOI:10.1128/AEM.01324-18

Reference

PMID:29581275

Authors

Crowe AM, Workman SD, Watanabe N, Worrall LJ, Strynadka NCJ, Eltis LD.

Title

IpdAB, a virulence factor in Mycobacterium tuberculosis, is a cholesterol ring-cleaving hydrolase.

Journal

Proc Natl Acad Sci U S A 115:E3378-E3387 (2018)
DOI:10.1073/pnas.1717015115

Sequence

[mtu:Rv3552]

LinkDB

DBGET integrated database retrieval system