KEGG ORTHOLOGY: K28230

ORTHOLOGY: K28230

Entry

K28230                      KO

Symbol

scdM1, fadE31

Name

acyl-CoA dehydrogenase [EC:1.3.99.-]

Pathway

map00984

Steroid degradation

map01120

Microbial metabolism in diverse environments

Reaction

R13484

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00984 Steroid degradation
    K28230  scdM1, fadE31; acyl-CoA dehydrogenase

Other DBs

COG:

COG1960

Genes

RGL:	CS053_01830

VAF:	D1115_22690

PRE:	PCA10_13440

PFUW:

PLAL:

PPUT:

PPUN:

PPUU:

PKC:

PFZ:	AV641_09540

PPSY:

AOC04_06365

PSET:

THL1_1416

PSIL:

PMA3_11830

PKE:	DLD99_14615

PUM:	HGP31_20670

PPSH:

PAZE:

PTAE:

PCAV:

PPHN:

PIZ:	LAB08_R40670

PKM:	PZ739_11740

PSHS:

PLAU:

PFOU:

PSKP:

PDEU:

PBUB:

PSML:

PSMZ:

PSWO:

PMOR:

PKH:	JLK41_05825

SDEG:

GOM96_01475

HARR:

HV822_17710

PPHA:

BVH74_17645

KAK:	Kalk_07790

SPL:

SHL:

COLW:

CBER:

PHA:

PTN:	PTRA_a1040(ivd)

PNG:	PNIG_a1091(ivd)

SNAN:

I6N98_06955

ZAL:	AZF00_05295

MSPN:

M8T91_14305

HJA:	BST95_08540

HALC:

AFUS:

PAQM:

MSEC:

MRZ:	KDW95_01155

EMP:	EZMO1_1291

SDF:	ACG33_00340

SOK:	D0B54_05320

SINI:

GT972_08425

FCE:	JN531_005420

GPB:	HDN1F_27440

REH:	H16_B0660(h16_B0660)

CNC:	CNE_2c06070(mmgC2)

CUH:	BJN34_30685

REU:	Reut_A1563

CTI:	RALTA_B0502

CBW:	RR42_s2330

COX:	E0W60_08245

CUK:	KB879_20745

CUPP:

CTP10_R38910

CUPA:

LPA45_23970

BUR:	Bcep18194_B1437

BCJ:

BCEN:

BCEO:

BCT:

BCED:

BCEP:

BPYR:

BCON:

BDF:	WI26_21290

BTEI:

BPSL:

BMEC:

BSTL:

BANN:

BARI:

BAEN:

BURK:

BURF:

BFN:

PBRY:

PPAI:

PVE:	UC34_06965

CABA:

SBC2_48870

CTT:	CtCNB1_1281

CTES:

O987_07315

CRJ:	QMY55_06825

DIH:	G7047_10885

SMIO:

CATMQ487_32110

DOE:	DENOEST_1369

DENI:

B9N43_04450

AZD:	CDA09_09650

THU:	AC731_008485

THAU:

C4PIVTH_4226

THAG:

CKCBHOJB_02316

MESS:

ABSY17_13335

AAK:	AA2016_3678

AMIS:

Amn_27680

AMIO:

N7E70_017980

GYJ:	AADW23_16390

FRB:	AB6B37_08140

NAR:

Saro_3756

NPP:	PP1Y_Mpl3014

NOV:	TQ38_027245

NOT:	C7W88_20780

NOR:	FA702_21070

NOVO:

IM701_15475 IM701_20450

SPHM:

SPHI:

SSAN:

SPKC:

SPHA:

SLAN:

SBIN:

SPCL:

SPOG:

SWI:

SPHD:

SPHB:

SPCA:

PHAO:

CNA:	AB433_04820

PHZ:	CHX26_05265

NTD:	EGO55_13740

CAEN:

K5X80_14675

HFO:	ABFZ83_09735

ERZ:	ER308_05800

EUZ:	DVS28_a3719

MTU:	Rv3562(fadE31)

MTV:

RVBD_3562

MTC:

MT3667

MRA:	MRA_3601(fadE31)

MTF:	TBFG_13595

MTB:	TBMG_03601

MTK:	TBSG_03628

MTZ:	TBXG_004055

MTG:	MRGA327_21995

MTI:	MRGA423_22510

MTE:	CCDC5079_3303

MTUR:

CFBS_3778(fadE31)

MTL:	CCDC5180_3255

MTO:	MTCTRI2_3626(fadE31)

MTD:	UDA_3562(fadE31)

MTN:	ERDMAN_3907(fadE31)

MTJ:	J112_19180

MTUB:

MT7199_3624

MTUE:

J114_19050

MTX:	M943_18310

MTUL:

TBHG_03502

MTUT:

HKBT1_3763(fadE31)

MTUU:

HKBT2_3772(fadE31)

MTQ:	HKBS1_3775(fadE31)

MBO:	BQ2027_MB3592(fadE31)

MBB:	BCG_3626(fadE31)

MBT:	JTY_3627(fadE31)

MBM:	BCGMEX_3624(fadE31)

MBK:	K60_037000

MBX:

BCGT_3428

MAF:	MAF_35740(fadE31)

MMIC:

RN08_3939

MCE:	MCAN_35731(fadE31)

MCQ:	BN44_110054(fadE)

MCV:	BN43_90060(fadE)

MCX:	BN42_90059(fadE)

MCZ:	BN45_100061(fadE)

MORY:

MO_003719

MPA:	MAP_0505c(fadE31)

MAO:

MAVI:

MAVU:

MAV:

MAVM:

MAA44156_00518(mmgC_2)

MIT:

MIA:

MID:

MYO:

MCHI:

MIR:

MMAL:

MLP:

MMAN:

MMAN_48030(fadE31)

MSER:

MTY59_24380(fadE31)

MSA:	Mycsm_05825

MUL:	MUL_4127(fadE31)

MMI:	MMAR_5051(fadE31)

MMAE:

MMARE11_48660(fadE31)

MLI:	MULP_05309(fadE31)

MPSE:

MPSD_52510(fadE31)

MSHO:

MSHO_05330(fadE31)

MMC:

MKM:

MJL:

MMM:

MKN:	MKAN_12045

MYV:	G155_26345

MYE:	AB431_26510

MHAD:

B586_04500

MDX:	BTO20_04535

MSHG:

MSG_04548(fadE31)

MFJ:	MFLOJ_40770(fadE31)

MSTO:

MSTO_44740(fadE31)

MSIM:

MSIM_29190(fadE31)

MSAK:

MSAS_29050(fadE31)

MKU:	I2456_25640

MLW:	MJO58_25040

MXE:	MYXE_05140(fadE31)

MNV:	MNVI_12430

MPAG:

C0J29_27715

MNM:	MNVM_23550

MGOR:

H0P51_25770

MCOO:

MCOO_27200

MBAI:

MB901379_04441(mmgC_21)

MSEO:

MSEO_34460(fadE31)

MHEK:

JMUB5695_00475(fadE31)

MGAU:

MGALJ_38380

MLJ:	MLAC_47420(fadE31)

MBRD:

MBRA_20080

MSHJ:

MSHI_38730(fadE31)

MMAM:

K3U93_22645

MSPG:

F6B93_20450

MOT:	LTS72_27955

MPAA:

MKK62_02445

MKY:	IWGMT90018_57390(fadE31)

MADI:

A7U43_06730

MWU:	PT015_15520

MYW:	BVC93_09220

MYJ:	BCA37_02775

MHAF:

ACEL92_03035

MSM:	MSMEG_6014

MSG:	MSMEI_5854(fadE31)

MSB:	LJ00_29735

MSN:	LI99_29740

MSH:	LI98_29745

MVA:

Mvan_5287

MGI:

Mflv_1479

MSP:	Mspyr1_46880

MCB:	Mycch_4657

MNE:	D174_24630

MYN:	MyAD_24165

MFT:	XA26_53350

MPHL:

MPHLCCUG_00511(mmgC_1)

MVQ:

MYVA_5197

MLL:	B1R94_25350

MRH:	MycrhN_2264

MTHN:

4412656_04085(caiA_8)

MHAS:

MHAS_03766

MDU:	MDUV_49140

MCHT:

MCHIJ_19450

MAUU:

NCTC10437_05045(fadE31)

MMAG:

MMAD_48450

MMOR:

MMOR_11940

MFX:	MFAL_32660

MAIC:

MAIC_05280

MIJ:	MINS_00630

MALV:

MALV_42350

MTY:	MTOK_22120

MPSC:

MARZ:

MGAD:

MHEV:

MSAR:

MANY:

MAUB:

MPOF:

MPHU:

MMUC:

MMAT:

MBOK:

MFG:	K6L26_05480

MSEI:

MSEDJ_02400

MFLV:

NCTC10271_00479(fadE31)

MCEE:

MCEL_37850

MMON:

EWR22_25400

MGO:	AFA91_10710

MHOL:

K3U96_03155 K3U96_25210

MSEN:

K3U95_25375

MPAE:

K0O64_26005

MRF:	MJO55_24070

MDF:	K0O62_25860

MCRO:

MGRO:

MAUS:

MFRE:

MBUG:

MYQ:	TUM20985_06510

MFLU:

HZU40_32950

MYH:	QU592_27335

MPAT:

MPNTM1_01940

MKR:	MKOR_35460

MPAK:

MIU77_02030

MAB:

MAB_0595c

MMV:	MYCMA_0304

MABB:

MASS_0565

MABL:

MMASJCM_0584

MCHE:

BB28_02840

MIZ:	BAB75_03590

MSTE:

MSTE_00553

MSAO:

MYCSP_02545

MSAL:

DSM43276_00513(acdA_3)

MJD:	JDM601_3718(fadE31)

MTER:

4434518_03720(fadE31)

MMIN:

MMIN_12420

MHIB:

MHIB_31070

MHER:

K3U94_20975

MVM:	MJO54_20870

MKK:	MU0083_003468

ASD:

AS9A_0942

NFA:	NFA_4810(fadE7)

NFR:	ERS450000_03755(bbsG_5)

NCY:	NOCYR_0511

NBR:	O3I_002765

NNO:	NONO_c05100

NSL:	BOX37_02230

NSR:	NS506_01274

NTP:	CRH09_03375

NOZ:	DMB37_23665

NOD:	FOH10_28635

NAH:	F5544_02700

NAD:	NCTC11293_01255(caiA_2)

NWL:	NWFMUON74_05050

NIE:	KV110_03095

NTC:	KHQ06_03590

NHU:	H0264_03905

NYA:	LTV02_28815

NGP:	LTT66_15505

NSPU:

IFM12276_01850

NYU:	D7D52_04570

NVU:	V7968_10185

RHA:	RHA1_ro04593

RER:

RER_08880

REY:

O5Y_03930

REB:	XU06_04170

RQI:	C1M55_04400

ROP:

ROP_45380

ROA:	Pd630_LPD01070

RPY:	Y013_19120

RBY:	CEJ39_05485

RAV:	AAT18_04015

RHW:	BFN03_15070

RRZ:	CS378_19660

RHQ:	IM25_08970

RHOD:

AOT96_14800

RRT:	4535765_00600(caiA_2)

RCR:	NCTC10994_02120(caiA_1)

RTM:	G4H71_07305

RKO:	JWS14_25295

RGO:	KYT97_23445

ROZ:	CBI38_04295

RPSK:

RGOR:

RHOP:

RHOO:

RHOU:

RHOW:

RHOJ:

RHOS:

RHOQ:

RHOY:

RHOH:

RHOX:

RHJS:

RSF:	OED52_02380

RHZQ:

RHZG:

RHBH:

RHPD:

RHON:

RHWB:

REQ:

PDEF:

PSOW:

WHR:	OG579_17680

GBR:

Gbro_0928

GPO:	GPOL_c40950

GOR:	KTR9_0829(fadE31)

GOQ:	ACH46_03330

GTA:	BCM27_05155

GOC:	CXX93_06520

GIT:	C6V83_04320

GRU:	GCWB2_04220(mmgC4)

GOM:	D7316_02446

GAV:	C5O27_00815

GOD:	GKZ92_04015

GOS:	QAD21_04170

GOJ:	GR168_04295

GAM:	GII34_18745

GPD:	GII33_03990

GJI:	H1R19_04095

GOI:	LK459_05040

GHN:	MVF96_04295

GAMI:

IHQ52_06875

GMG:	NWF22_15835

GSI:	P5P27_15735

GOO:	HUN08_03035

GOP:	ACE11G_03210

SPIN:

KV203_17320

TPR:

Tpau_3838

TSM:	ASU32_21865

TPUL:

TPB0596_41780

DTM:	BJL86_0712

DIT:	C3V38_09305

DIZ:	CT688_03225

DPC:	A6048_03170

DLU:	A6035_03465

DKN:	NHB83_03020

DCD:	VYL96_03250

DID:	GJR88_01043

TOY:	FO059_13905

SMA:	SAVERM_6196(fadE20)

SGR:

SGB:

SFI:

SANL:

SGRF:

SCYE:

SCB:	SCAB_68661

SVL:	Strvi_3829

SRC:	M271_12405 M271_44215

SMAL:

SAUO:

SSOI:

SANT:

SBH:	SBI_01738(fadE8)

SVE:

SVEN_1668

SDV:	BN159_6430(fadE20)

SCI:	B446_10600

SVT:	SVTN_35790

STRE:

GZL_01219

SLD:

T261_0448

SLC:	SL103_14995

STRM:

M444_10290

SPRI:

SPRI_5488

SCZ:	ABE83_27905

SCX:	AS200_32845

SRW:	TUE45_02548(mmgC_4)

SCLF:

BB341_21950

SGS:	AVL59_37080

STSI:

A4E84_00860

SALW:

CP975_30845

SGM:	GCM10017557_61910

SCAD:

DN051_28295

SPHW:

NFX46_30895

SLS:	SLINC_2350

SNR:	SNOUR_05145

SALU:

SALL:

SPLU:

SSIA:

SVU:	B1H20_06980

SPUN:

BFF78_01855

SGV:	B1H19_37105

SLAU:

SLA_1569

SALF:

SMD44_07220

SALJ:

SMD11_0786

SLX:	SLAV_27260(mmgC12)

STRO:

STRMOE7_04835

SFK:

KY5_7026c

SNZ:	DC008_08475

SGE:	DWG14_08130

SRJ:

SRO_5446

SLK:	SLUN_09870

SDX:	C4B68_30100

SGD:	ELQ87_29215

SQZ:	FQU76_06710

SCYA:

EJ357_11890

STIR:

DDW44_03355

SKA:	CP970_04930

SGZ:	C0216_23165

SVN:	CP980_24815

SNK:	CP967_03145

SHAW:

CEB94_10950

SRK:	FGW37_28030

SFIC:

EIZ62_25025

SGAL:

CP966_08950

SSPO:

DDQ41_02725

SFY:	GFH48_29850

SAQU:

EJC51_13660

SGF:	HEP81_05752

SCAV:

SRIM:

SSUB:

SPHV:

STSU:

SCHA:

SGX:	H4W23_38425

SCOE:

CP976_11725

SSPB:

CP982_33775

SNF:	JYK04_02680

SPLA:

SBRO:

STUI:

SATA:

SHUN:

SCYG:

S1361_11160(mmgC4)

SFEU:

IM697_11810

SDW:	K7C20_03245

SCAL:

I6J39_07175

SAUH:

SU9_002460

SROI:

IAG44_03070

SXN:	IAG42_26545

SHK:	J2N69_32340

SANU:

K7396_32180

SGOB:

test1122_18985

SINE:

KI385_05775

SLF:	JEQ17_34390

SDEC:

SAOV:

SDUR:

SYAN:

SRUG:

SAKB:

STAA:

SNIG:

SCAE:

STUB:

SSPN:

SCIR:

SXT:	KPP03845_102244

SLON:

LGI35_13960

STUD:

STRTU_006616

SGK:	PET44_08910

SYUN:

MOV08_04935

SJN:	RI060_31880

SCYN:

N8I84_11305

SOV:	QZH56_03680

SFIY:

F0344_28305

SHAU:

K9S39_08245

SKG:	KJK29_28830

SCOA:

QU709_32705

SLAI:

P8A22_33535

SROC:

RGF97_25940

SFP:	QUY26_06140

STTN:

BSL84_08755

SINN:

ABB07_34025

KBU:	Q4V64_12715

SLUO:

STPB:

SRPA:

SMIB:

SCAJ:

STRW:

STRL:

STSD:

SRPZ:

SCHE:

SCAT:

STII:

STIC:

SABD:

SPAZ:

SMOD:

SPOF:

STBR:

STAC:

STVB:

SSOC:

SSLI:

STYI:

C9F11_32910(mmgC10)

SCIT:

SSIR:

SEXP:

SFLU:

SSTO:

STGO:

STCM:

STID:

STCZ:

STSG:

STHU:

STRQ:

SCT:

SCY:	SCATT_56170

KAB:	B7C62_06865

YIA:	LO772_20285

STRH:

GXP74_18345

AGLA:

OIE69_15310

MRN:	K8F61_15925

MSUF:

KV394_02690

MWN:	QNO26_01555

ARL:	AFL94_16430

ARY:	ATC04_01440

ASUN:

KG104_08955

ARTA:

OL239_10530

GPR:	JQN66_16745

PAEY:

KUF55_17825

JAI:	V1351_13890

SERJ:

SGUI_2666

NCA:

Noca_2769

NDK:	I601_0621(acdA_4)

NBE:	Back2_27280

NANO:

G5V58_09815

NARO:

CFH99_13490

NPI:	G7071_15910

NPC:	KUV85_04310 KUV85_14970

NMAR:

HPC71_09575

NFC:	KG111_08345

NBI:	SHK19_12440

NOF:	MF408_21070

NOCR:

OSR43_09620

NOCW:

ABFU82_07520

NOCL:

KM427_03340 KM427_12600

NOCD:

QJ852_14465 QJ852_24880

NOCQ:

QI633_11935

PSIM:

KR76_14445

AEZ:	C3E78_14075

AEB:	C6I20_03315

TCU:

ACTW:

AMAZ:

ACIR:

AWS:	ACN3XK_49550 ACN3XK_50285 ACN3XK_68870

SPIQ:

OHA34_00110 OHA34_33565

ACTQ:

OG417_40430

SRO:

Sros_1985

NOA:	BKM31_34700

NCX:	Nocox_09485(mmgC3)

NGN:	LCN96_10705

NFS:	OIE67_36325

FRI:	FraEuI1c_1263 FraEuI1c_3241

AMD:

AMN:

AMM:

AMZ:

AOI:

AJA:	AJAP_26340

AMQ:	AMETH_4457

AMYC:

CU254_23955

AMYB:

BKN51_05095

AAB:	A4R43_16010

AMYY:

YIM_33160(acdA11)

AORI:

SD37_13540

AACD:

LWP59_05570 LWP59_29170

APRT:

AROO:

ATHM:

ARHD:

AMOG:

ACYN:

ACOR:

AMYZ:

ANW:	QP939_43970

AMYD:

ABAR:

AMYE:

AMYS:

PPEL:

PSDS:

KAL:

KUT:	JJ691_29500

KBR:	Q4V65_00890

KPHY:

AOZ06_42715

LED:	BBK82_38885

LXR:	ACRSBM_25880

PMAD:

BAY61_16155

SACE:

GIY23_13160

CROS:

N8J89_29345

STP:	Strop_2617

SAQ:

Sare_2816

MICB:

MicB006_5703

MCHL:

PVK74_03285

AMS:	AMIS_19250

AIH:	Aiant_18760

ACTL:

L3i22_084280

ASIC:

Q0Z83_065510

AOU:	ACTOB_004130

ACTE:

ACTI_41270

DVC:	Dvina_21530

DFU:	Dfulv_15915 Dfulv_25815

DROS:

DAUR:

DMAT:

DACT:

CAI:

JCY:	M6B22_17410

ABAI:

IMCC26256_111844

CWO:

Cwoe_2351

ADAE:

ACE2AJ_17045

IAM:	HC251_18125

IMA:	PO878_16960

DHI:	LH044_15625

AHAI:

AB8619_00185

LEPV:

J4558_08145

» show all

Reference

PMID:12676694

Authors

Horinouchi M, Hayashi T, Koshino H, Yamamoto T, Kudo T

Title

Gene encoding the hydrolase for the product of the meta-cleavage reaction in testosterone degradation by Comamonas testosteroni.

Journal

Appl Environ Microbiol 69:2139-52 (2003)
DOI:10.1128/AEM.69.4.2139-2152.2003

Sequence

[ctt:CtCNB1_1281]

Reference

PMID:37815342

Authors

Horinouchi M, Hayashi T.

Title

Identification of "missing links" in C- and D-ring cleavage of steroids by Comamonas testosteroni TA441.

Journal

Appl Environ Microbiol 89:e0105023 (2023)
DOI:10.1128/aem.01050-23

Reference

PMID:28377529

Authors

Crowe AM, Casabon I, Brown KL, Liu J, Lian J, Rogalski JC, Hurst TE, Snieckus V, Foster LJ, Eltis LD.

Title

Catabolism of the Last Two Steroid Rings in Mycobacterium tuberculosis and Other Bacteria.

Journal

mBio 8:e00321-17 (2017)
DOI:10.1128/mBio.00321-17

Sequence

[mtu:Rv3562]

LinkDB

DBGET integrated database retrieval system