KEGG ORTHOLOGY: K28414

ORTHOLOGY: K28414

Entry

K28414                      KO

Symbol

DENND10

Name

DENN domain-containing protein 10

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K28414  DENND10; DENN domain-containing protein 10
Membrane trafficking [BR:ko04131]
Endosome - Lysosome transport
  Rab GTPases and associated proteins
   Rab associated proteins
    K28414  DENND10; DENN domain-containing protein 10

Other DBs

GO:

0005085

Genes

HSA:	404636(DENND10)

PTR:	107966234(DENND10)

PPS:	100983138(DENND10)

GGO:	101139734(DENND10)

PON:	100453843(DENND10)

PPYG:

129006080(DENND10)

NLE:	100591568(DENND10)

HMH:	116482974(DENND10)

SSYN:

129465409(DENND10)

MCC:	713269(FAM45A)

MCF:	101925370(DENND10)

MTHB:

126962673

MNI:	105467721(FAM45A)

CSAB:

103216822(FAM45A) 103247254

CATY:

105577967(FAM45A)

PANU:

101022844(DENND10)

TGE:	112630954(FAM45A)

MLEU:

105554564(FAM45A)

RRO:	104672230(DENND10)

RBB:	108513864(FAM45A)

TFN:	117065935(DENND10)

PTEH:

111550739(DENND10)

CANG:

105503414(FAM45A)

CJC:	100399233(DENND10)

SBQ:	101039750(FAM45A)

CIMI:

108289588(DENND10)

ANAN:

105714179(DENND10)

CSYR:

103275857(FAM45A)

MMUR:

105857044(FAM45A)

LCAT:

123650212(DENND10)

ERUF:

138376027(DENND10)

PCOQ:

105808694(FAM45A)

OGA:	100946921(FAM45A)

MMU:	67894(Dennd10)

MCAL:

110285478(Fam45a)

MPAH:

110321265(Fam45a)

RNO:	308009(Dennd10)

MCOC:

116104069(Dennd10)

ANU:	117714202(Dennd10)

ASYL:

127685276(Dennd10)

MMIU:

308417910(DENND10)

MUN:	110562376(Dennd10)

CGE:	100752411(Dennd10)

MAUA:

101833366(Dennd10)

PROB:

127233256(Dennd10)

PLEU:

114686119(Dennd10)

PMAV:

102915356(Dennd10)

MORG:

121454526(Dennd10)

MFOT:

126505641

AAMP:

119822316(Dennd10)

CNL:	130880405(Dennd10)

NGI:	103729288(Fam45a)

HGL:	101719786(Fam45a)

CPOC:

100716960(Fam45a)

CCAN:

109700990(Fam45a)

DORD:

105989759(Fam45a)

DSP:	122126848(Dennd10)

DMER:

138803926(Dennd10)

PLOP:

125346001(Dennd10)

NCAR:

124984420

SVUL:

306659536(DENND10)

MMMA:

107152820(Dennd10)

ITI:	101975188(Dennd10)

SCIL:

308634152(DENND10)

MAVE:

308261785(DENND10)

OCU:	100354060(DENND10)

OPI:	101524611(DENND10)

OCZ:	121164109(DENND10)

TUP:	102488192(FAM45A)

GVR:	103598820(FAM45A)

CFA:	477837(DENND10)

CLUD:

112672415(DENND10)

VVP:	112916548(FAM45A)

VLG:	121484549(DENND10)

NPO:	129493796(DENND10)

AML:	100478299(DENND10)

UMR:	103659327(DENND10)

UAH:	113251990(DENND10)

UAR:	123796005(DENND10)

ELK:

111145262

LLV:

125084342

MPUF:

101692702(FAM45A)

MNP:	132016820(DENND10)

MLK:	131830628(DENND10)

NVS:	122901159(DENND10)

MMAQ:

308354799(DENND10)

ORO:	101385804(FAM45A)

EJU:	114223074(FAM45A)

ZCA:	113921878(DENND10)

MLX:	118026953(DENND10)

MANO:

123846901(DENND10)

NSU:	110589077(DENND10)

LWW:	102734277(DENND10)

FCA:	101088191(DENND10)

PYU:	121037293(DENND10)

PCOO:

112854249(FAM45A)

PBG:	122493305(DENND10)

PVIV:

125148246(DENND10)

LRUF:

124507178

LGF:	123577147(DENND10)

AJU:	106969371(DENND10)

PTG:	102961113(FAM45A)

PPAD:

109272975(FAM45A)

PUC:	125918344 125918345

PLEZ:

122201852(DENND10)

HHV:	120235161(DENND10)

CCRU:

144244232(DENND10)

BTA:	534370(DENND10)

BOM:	102270041(DENND10)

BIU:	109552984(FAM45A)

BJV:	133239468(DENND10)

BBUB:

102390261(DENND10)

BKE:	129636633(DENND10)

BBIS:

105002570(FAM45A)

CHX:	102189824(FAM45A)

OAS:	101106220(DENND10)

OCAN:

138427609(DENND10)

BTAX:

128067841(DENND10)

CSUM:

138070285(DENND10)

ODA:	120873861(DENND10)

CCAD:

122445872(DENND10)

MREE:

136160162(DENND10)

OVR:	110138562(DENND10)

MBEZ:

129555306(DENND10)

SSC:	100155371(FAM45A)

CFR:	102519050(DENND10)

CBAI:

105080774(FAM45A)

CDK:	105104213(DENND10)

VPC:	102538643(DENND10)

BACU:

103005056(FAM45A)

BMUS:

118882722(DENND10)

LVE:	103072096(FAM45A)

OOR:	101276411(DENND10)

LALB:

132506989(DENND10)

GMF:	115843411(DENND10)

DDP:	132439575(DENND10)

SCOO:

307175604(DENND10)

PCRS:

137208715(DENND10)

DLE:	111172259(DENND10)

PCAD:

102979229(DENND10)

PSIU:

116741730(DENND10)

PPHC:

136136299(DENND10)

NASI:

112406984(FAM45A)

HAMP:

307051454(DENND10)

ECB:	100065995(FAM45A)

EPZ:	103554629(DENND10)

EAI:	106836368(DENND10)

MYB:	102247201(FAM45A)

MYD:	102758042(FAM45A)

MMYO:

118669692(DENND10)

MLF:	102425379(FAM45A)

MDT:	132214394(DENND10)

MYUM:

139021693(DENND10)

PKL:	118719534(DENND10)

EFUS:

103288599(DENND10)

POTS:

308234247(DENND10)

MNA:	107532092(FAM45A)

DRO:	112300285(FAM45A)

SHON:

118996305(DENND10)

AJM:	119040060(DENND10)

PDIC:

114497649(DENND10)

PHAS:

123829067(DENND10)

MMF:	118632206(DENND10)

PPAM:

129077209(DENND10)

HAI:	109383011(FAM45A)

RFQ:	117035965(DENND10)

RHII:

308508331(DENND10)

PALE:

102894271(FAM45A)

PGIG:

120608883(DENND10)

PVP:	105291450(FAM45A)

RAY:	107509754(DENND10)

MJV:	108396054(DENND10)

TOD:	119233376(DENND10)

SARA:

101554233(FAM45A)

SFUM:

130029884(DENND10)

SETR:

125994936(DENND10)

LAV:	100666068(FAM45A)

TMU:

101354168

ETF:	101648447(DENND10)

DNM:	101433737(FAM45A)

MDO:	100020407(FAM45A)

GAS:	123238189(DENND10)

SHR:	100913450(DENND10)

AFZ:

127551631

PCW:	110209568(FAM45A)

TVP:	118829386(DENND10)

PBRV:

138169539(DENND10)

MLAO:

141521223(DENND10)

OAA:	100084139(DENND10)

TACU:

119938580(DENND10)

GGA:	423928(FAM45A)

PCOC:

116231580(DENND10)

MGP:	100539206(DENND10)

CJO:	107316178(DENND10)

TPAI:

128077780(DENND10)

LMUT:

125692905(DENND10)

NMEL:

110399967(FAM45A)

APLA:

101793898(DENND10)

AACU:

137859655(DENND10)

OJA:	118168775(DENND10)

ACYG:

106045236(DENND10)

ABRC:

308197246(DENND10)

CATA:

118248625(DENND10)

AFUL:

116491510(DENND10)

TGU:	100227007(DENND10)

LSR:	110469987(DENND10)

VMC:	128811073(DENND10)

AIB:	137478366(DENND10)

SCAN:

103813794(DENND10)

PMOA:

120502187(DENND10)

OTC:	121341943(DENND10)

PRUF:

121350361(DENND10)

ATRC:

139599027(DENND10)

MATE:

118688383(DENND10)

MAEN:

136559662(DENND10)

GFR:	102035758(FAM45A)

FAB:	101814613(FAM45A)

OMA:	130254806(DENND10)

PHI:	102102306(FAM45A)

PMAJ:

107206870(DENND10)

CCAE:

111931362(FAM45A)

CCW:	104697861(DENND10)

CBRC:

103624021(FAM45A)

ACOE:

138112673(DENND10)

ETL:	114060958(FAM45A)

ZAB:	102064130(FAM45A)

ZLE:	135449805(DENND10)

ACHL:

103808159(FAM45A)

SVG:	106859501(FAM45A)

MMEA:

130582754(DENND10)

HRT:	120756032(DENND10)

SATI:

136363990(DENND10)

CFAI:

136293810(DENND10)

CCIC:

134046060(DENND10)

NNT:	104410117(FAM45A)

SHAB:

115607928(DENND10)

POCC:

134172274(DENND10)

FPG:	101919918(FAM45A)

FCH:	102050529(FAM45A)

FRS:	119153620(DENND10)

CCRI:

104160046(FAM45A)

ACUN:

113481701(FAM45A)

ANOC:

141961166(DENND10)

SURA:

141946120(DENND10)

TALA:

104356028(DENND10)

ACHC:

115347911(DENND10)

HALD:

104310980(FAM45A)

HLE:	104830197(FAM45A)

AGEN:

126042665

HHAR:

128146823(DENND10)

BBUT:

142030385(DENND10)

GCL:

127018018

CSTI:

104560537(FAM45A)

LDI:	104345705(FAM45A)

MNB:	103781650(FAM45A)

DPUB:

104309138(FAM45A)

PPUS:

135175885(DENND10)

IIN:	128968165(DENND10)

AVIT:

104276579(FAM45A)

BRHI:

104497491(FAM45A)

EGZ:	104128612(DENND10)

NNI:	104022357(FAM45A)

PCRI:

104034774(FAM45A)

PCAO:

104051720(FAM45A)

PARX:

142063489(DENND10)

PADL:

103918656(FAM45A)

AFOR:

103897919(FAM45A)

FGA:	104073701(FAM45A)

CBOR:

142084438(DENND10)

GSTE:

104254288(FAM45A)

CBOY:

140655708(DENND10)

MAME:

142411117(DENND10)

CLV:	102094820(FAM45A)

CNIC:

135991173(DENND10)

NMAY:

308042185(DENND10)

MUI:	104534071(FAM45A)

PGUU:

104470408(FAM45A)

PLET:

104628817(FAM45A)

EHS:	104511778(FAM45A)

CMAC:

104473799(FAM45A)

CUCA:

104067769(DENND10)

PCUR:

138724063(DENND10)

TEO:	104384617(FAM45A)

BREG:

104637013(FAM45A)

GAME:

129208486(DENND10)

OHA:	104332358(FAM45A)

ACAR:

104518398(FAM45A)

CEUR:

306720063(DENND10)

CPEA:

104394383(FAM45A)

HEK:	139798610(DENND10)

CVF:	104283477(FAM45A)

RTD:	128911857(DENND10)

CRID:

134517596(DENND10)

LMIC:

141745420(DENND10)

NARQ:

141472138(DENND10)

AAM:	106489511(FAM45A)

AROW:

112967322(FAM45A)

NPD:	112957009(FAM45A)

TGT:	104575667(FAM45A)

DNE:	112987997(FAM45A)

SCAM:

104140110(FAM45A)

ASN:	102383280(FAM45A)

AMJ:	102575066(FAM45A)

CPOO:

109324077(FAM45A)

GGN:	109287661(FAM45A)

PSS:	102450118(DENND10)

CIZ:	142015544(DENND10)

CMY:	102939449(DENND10)

CCAY:

125640102(DENND10)

LKP:	140914998(DENND10)

NDS:	141991140(DENND10)

DCC:	119858366(DENND10)

CPIC:

101953373(DENND10)

TST:	117880427(DENND10)

EOB:	135881213(DENND10)

CABI:

116825071(DENND10)

MRV:	120369248(DENND10)

EMQ:	137161820(DENND10)

ACS:	100568278(fam45a)

ASAO:

132770998(DENND10)

PVT:	110075322(FAM45A)

SUND:

121926082(DENND10)

PBI:	103064121(FAM45A)

PMUR:

107290578(FAM45A)

CTIG:

120314278(DENND10)

TSR:	106540241(FAM45A)

PGUT:

117678754(DENND10)

PCAE:

139318185(DENND10)

APRI:

131200768(DENND10)

PTEX:

113439139(FAM45A)

NSS:	113413552(FAM45A)

VKO:	123028213(DENND10)

PMUA:

114597437(FAM45A)

PRAF:

128414184(DENND10)

ZVI:	118096316(DENND10)

HCG:	128348690(DENND10)

GJA:	107106720(FAM45A)

STOW:

125437690(DENND10)

EMC:	129331864(DENND10)

NPR:	108802878(FAM45A)

RTEM:

120946783(DENND10)

ACAT:

141105723(DENND10)

PADS:

140340043(DENND10)

PWL:	138300208(DENND10)

MUO:	115469877(DENND10)

GSH:	117359884(DENND10)

DRE:	556203(dennd10)

DAES:

130239411(dennd10)

SRX:	107711433 107733722

SANH:

107698741(fam45a)

SGH:	107585262 107602482

CCAR:

109062237 109087616

CAUA:

113057131 113071220 113112889

CGIB:

127969912 128026305

PTET:

122356597(dennd10)

LROH:

127175486(dennd10)

GRF:	141326332(dennd10)

OMC:	131552762(dennd10)

PPRM:

120479715(dennd10)

RKG:	130099722(dennd10)

SCEP:

307148873(dennd10)

MAMB:

125276780(dennd10)

CIDE:

127524419

CERY:

137020480(dennd10)

MASI:

127412345 127413594

TROS:

130559748(dennd10)

TDW:	130431245(dennd10)

MANU:

129416049(dennd10)

PDAB:

135787169(dennd10)

IPU:	108263166(dennd10)

IFU:	128605877(dennd10)

PHYP:

113543142(fam45a)

SMEO:

124395756(dennd10)

TFD:	113660993(dennd10)

TVC:	132847475(dennd10)

CGAR:

128528816(dennd10)

NGRA:

132889586(dennd10)

TRN:	134314599(dennd10)

AMEX:

103034200(dennd10)

CMAO:

118810629(dennd10)

EEE:	113579913(fam45a)

TRU:	101068903(dennd10)

TFS:	130533504(dennd10)

TNG:	GSTEN00009379G001

NCC:	104954178(fam45a)

TBEN:

117499392(dennd10)

CGOB:

115020108(fam45a)

PGEO:

117459684(dennd10)

GACU:

117552208(dennd10)

EMAC:

134858848(dennd10)

ELY:	117248509(dennd10)

EFO:	125903679(dennd10)

PLEP:

121954383(dennd10)

SLUC:

116039400(dennd10)

SVIT:

144532269(dennd10)

ECRA:

117960703(dennd10)

ESP:	116675711(dennd10)

PFLV:

114572334(fam45a)

PFLT:

120548231(dennd10)

GAT:	120820247(dennd10)

PPUG:

119214362(dennd10)

AFB:	129092097(dennd10)

CLUM:

117743813(dennd10)

PSWI:

130207347(dennd10)

CANA:

137780183(dennd10)

TBU:	306746521(dennd10)

CVE:	137884300(dennd10)

AMIR:

142933085(dennd10)

MSAM:

119917075(dennd10)

SCHU:

122884837(dennd10)

EARM:

139294078(dennd10)

CUD:	121511017(dennd10)

SPUL:

138588168(dennd10)

LMIX:

132975980(dennd10)

HTC:	141795375(dennd10)

ALAT:

119033325(dennd10)

ASTR:

137604193(dennd10)

PKLU:

139210470(dennd10)

LCO:	104921873(fam45a)

AMMM:

307257240(dennd10)

MZE:	101470154(dennd10)

ONL:	100703869(fam45a)

OAU:	116318776(dennd10)

OLA:	101158629(fam45a)

OML:	112162136(dennd10)

CSAI:

133463428(dennd10)

XMA:	102226198(fam45a)

XCO:	114137633(fam45a)

XHE:	116712816(dennd10)

PRET:

103477134(dennd10)

PFOR:

103148231(fam45a)

PLAI:

106960024(fam45a)

PMEI:

106903929(fam45a)

GAF:	122842167(dennd10)

PPRL:

129352597(dennd10)

CVG:	107088279(fam45a)

CTUL:

119799537(dennd10)

GMU:	124859102(dennd10)

NFU:	107375549(fam45a)

KMR:	108250952(dennd10)

ALIM:

106525599(fam45a)

NWH:	119417464(dennd10)

LTU:	140313319(dennd10)

MCEP:

125019212(dennd10)

AOCE:

111573110(dennd10)

EJA:	138195604(dennd10)

BFRE:

138615999(dennd10)

LCF:	108886264(dennd10)

CSEM:

103387505(fam45a)

POV:	109636344(fam45a)

SSEN:

122781395(dennd10)

SSOE:

131473701(dennd10)

HHIP:

117775091(dennd10)

HSP:	118118721(dennd10)

PPLT:

128453048(dennd10)

SMAU:

118283288(dennd10)

SDU:	111220731(fam45a)

SLAL:

111669566(fam45a)

XGL:	120796708(dennd10)

HCQ:	109523093(fam45a)

SSCV:

125979025(dennd10)

SBIA:

133509650(dennd10)

PEE:	133409588(dennd10)

PTAO:

133485817(dennd10)

BPEC:

110162207(fam45a)

ENY:	140351489(dennd10)

MALB:

109960277(fam45a)

BSPL:

114870720(dennd10)

SJO:	128372412(dennd10)

SSCO:

133991662(dennd10)

TTY:	137196721(dennd10)

GMH:	115560144(dennd10)

SASA:

106576813 106604714

STRU:

115153019 115193991

OTW:	112252756 112252815

OMY:	110502282 110526492

OGO:	124038120 124040818

ONE:	115113380 115135295

OKI:	109889785 109899593

OKE:	118369517 118401962(dennd10)

OMM:	135510845 135512469(dennd10)

OCLA:

139381986 139409895

SALP:

111951927 111977381

SNH:	120017895 120046469

SFON:

129836122 129853435(dennd10)

CCLU:

121553617 121568967

ELS:	105026562(fam45a)

OEP:	134022429(dennd10)

AANG:

118218210(dennd10)

AROT:

135244508(dennd10)

CCOG:

133117924(dennd10)

LOC:	102683796(fam45a)

PSPA:

121326141(dennd10)

ARUT:

117417749(dennd10)

PSEX:

120522936(dennd10)

LCM:	102346214(FAM45A)

CMK:	103185214(dennd10)

RTP:	109923024(dennd10)

CPLA:

122561245(dennd10)

CPUN:

140463410(dennd10)

HOC:	132826314(dennd10)

SCAU:

119950740(dennd10)

LERI:

129704073(dennd10)

HAKA:

140715519(dennd10)

PMRN:

116940623(DENND10)

LRJ:	133343458(DENND10)

BFO:

BBEL:

CIN:

CLEP:

SPU:

LPIC:

LVG:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:

PFLL:

TCA:

TMOL:

ATD:

AGB:

DVV:

NVL:

DCOR:

CCRN:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BFER:

139997499(LOC139997499)

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

APUR:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

ACOC:

MZT:

CCOA:

TCZ:

TSEP:

PBAR:

VEM:

COBS:

TLN:

TAME:

TNY:	139769633 139769653

HST:	105184120 105185310 112590559

DQU:

CFO:

FEX:

PMEC:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

CTYP:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

NPT:

NFB:

NLO:

NVG:

AROA:

CLEC:

HHAL:

NLU:

LDA:

HVI:

MQU:

PHU:	Phum_PHUM217700

FOC:

TPAL:

ZNE:

CSEC:

PAME:

SGRE:

BROR:

IEL:	124154244(LOC124154244)

HAMR:

FCD:

ISC:

DSV:

DALB:

RSAN:

RMP:

VDE:

VJA:

GOE:

DPTE:

DFR:

CSCU:

CVS:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

LGI:	LOTGIDRAFT_239462

PVUL:

PCAN:

LSAX:

BARL:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

YBA:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

LLON:

NVE:

EPA:

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:	100201955(LOC100201955)

HSY:

130644903

RES:

135696482

TAD:	TRIADDRAFT_64371

AQU:

100641497

CCLM:

134193759

MBR:	MONBRDRAFT_23538

DDI:	DDB_G0268448(fam45)

DPP:	DICPUDRAFT_41536

DFA:	DFA_10788(fam45)

ACAN:

ACA1_294890

» show all

Reference

PMID:30771381

Authors

Zhang J, Zhang K, Qi L, Hu Q, Shen Z, Liu B, Deng J, Zhang C, Zhang Y

Title

DENN domain-containing protein FAM45A regulates the homeostasis of late/multivesicular endosomes.

Journal

Biochim Biophys Acta Mol Cell Res 1866:916-929 (2019)
DOI:10.1016/j.bbamcr.2019.02.006

Sequence

[hsa:404636]

LinkDB

DBGET integrated database retrieval system