KEGG ORTHOLOGY: K28472

ORTHOLOGY: K28472

Entry

K28472                      KO

Symbol

HSD17B14

Name

D-threo-aldose 1-dehydrogenase [EC:1.1.1.122]

Pathway

map00051

Fructose and mannose metabolism

map00053

Ascorbate and aldarate metabolism

Reaction

R07675

L-galactose:NAD+ 1-oxidoreductase

R08926

L-fucose:NAD+ 1-oxidoreductase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00051 Fructose and mannose metabolism
    K28472  HSD17B14; D-threo-aldose 1-dehydrogenase
   00053 Ascorbate and aldarate metabolism
    K28472  HSD17B14; D-threo-aldose 1-dehydrogenase
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.122  D-threo-aldose 1-dehydrogenase
     K28472  HSD17B14; D-threo-aldose 1-dehydrogenase

Other DBs

GO:

0047834

Genes

HSA:	51171(HSD17B14)

PTR:	747021(HSD17B14)

PPS:	100995043(HSD17B14)

GGO:	129528627(HSD17B14)

PON:	100447666(HSD17B14)

PPYG:

129021133(HSD17B14)

HMH:	116478233(HSD17B14)

SSYN:

129459295(HSD17B14)

MCC:	106994816(HSD17B14)

MCF:	102144144(HSD17B14)

MTHB:

126943592

CSAB:

103234998(HSD17B14)

CATY:

105595257(HSD17B14)

MLEU:

105539206(HSD17B14)

RRO:	104666547(HSD17B14)

RBB:	108523617(HSD17B14)

TFN:	117091528(HSD17B14)

CANG:

105514793(HSD17B14)

CJC:	103790011(HSD17B14)

SBQ:	101038719(HSD17B14)

CIMI:

108283901(HSD17B14)

ANAN:

105724078(HSD17B14)

CSYR:

103249906(HSD17B14)

MMUR:

105865592(HSD17B14)

LCAT:

123623852(HSD17B14)

PCOQ:

105809412(HSD17B14)

OGA:	100947420(HSD17B14)

MMU:	66065(Hsd17b14)

MCAL:

110299387(Hsd17b14)

RNO:	691018(Hsd17b14)

MCOC:

116102211(Hsd17b14)

ANU:	117694174(Hsd17b14)

ASYL:

127692906(Hsd17b14)

CGE:	100752644(Hsd17b14)

PLEU:

114684673(Hsd17b14)

MORG:

121463223(Hsd17b14)

MFOT:

126488098

AAMP:

119803093(Hsd17b14)

NGI:	103743631(Hsd17b14)

HGL:	101716482(Hsd17b14)

CPOC:

100727836(Hsd17b14)

CCAN:

109682678(Hsd17b14)

DSP:	122125796(Hsd17b14)

DMER:

138812822(Hsd17b14)

PLOP:

125338867(Hsd17b14)

MMMA:

107151274(Hsd17b14)

ITI:	120887890(Hsd17b14)

OPI:	101532902(HSD17B14)

OCZ:	121154851(HSD17B14)

TUP:	102472628(HSD17B14)

GVR:	103587756(HSD17B14)

CFA:	476420(HSD17B14)

CLUD:

112645185(HSD17B14)

VVP:	112931243(HSD17B14)

VLG:	121484341(HSD17B14)

NPO:	129500838(HSD17B14)

AML:	100477891(HSD17B14)

UMR:	103657102(HSD17B14)

UAH:	113243331(HSD17B14)

UAR:	123776246(HSD17B14)

ELK:

111160735

LLV:

125089079

MPUF:

101690690(HSD17B14)

MNP:	132004943(HSD17B14)

MLK:	131817774(HSD17B14)

NVS:	122911851(HSD17B14)

ORO:	101373220(HSD17B14)

EJU:	114199636(HSD17B14)

ZCA:	113936271(HSD17B14)

MLX:	117998238(HSD17B14)

NSU:	110572848(HSD17B14)

LWW:	102726961(HSD17B14)

FCA:	101080341(HSD17B14)

PYU:	121018743(HSD17B14)

PCOO:

112850784(HSD17B14)

PBG:	122494857(HSD17B14)

PVIV:

125153469(HSD17B14)

LRUF:

124511934

LGF:	123578080(HSD17B14)

AJU:

106988683

PTG:	102970646(HSD17B14)

PPAD:

109253106(HSD17B14)

PUC:

125915210

PLEZ:

122208652(HSD17B14)

HHV:	120243371(HSD17B14)

BTA:	282652(HSD17B14)

BOM:	102281531(HSD17B14)

BIU:	109572624(HSD17B14)

BBUB:

102396845(HSD17B14)

BBIS:

104995623(HSD17B14)

CHX:	102179697(HSD17B14)

OAS:	101123575(HSD17B14)

CSUM:

138096464(HSD17B14)

ODA:	120872169(HSD17B14)

CCAD:

122420324(HSD17B14)

MREE:

136161522(HSD17B14)

MBEZ:

129546578(HSD17B14)

SSC:	100523496(HSD17B14)

CFR:	102513116(HSD17B14)

CBAI:

105062605(HSD17B14)

CDK:	105102897(HSD17B14)

VPC:	102545136(HSD17B14)

BACU:

103018712(HSD17B14)

BMUS:

118885907(HSD17B14)

LVE:	103082521(HSD17B14)

OOR:	101287135(HSD17B14)

LALB:

132509931(HSD17B14)

GMF:	115862193(HSD17B14)

DDP:	132416010(HSD17B14)

DLE:	111180514(HSD17B14)

PCAD:

102997039(HSD17B14)

PPHC:

136140646(HSD17B14)

ECB:	100051311(HSD17B14)

EPZ:	103553319(HSD17B14)

EAI:	106838261(HSD17B14)

DRO:	112310183(HSD17B14)

AJM:	119043414(HSD17B14)

PDIC:

114511483(HSD17B14)

PHAS:

123830195(HSD17B14)

PPAM:

129082693(HSD17B14)

HAI:	109391075(HSD17B14)

RFQ:	117035397(HSD17B14)

MJV:	108400321(HSD17B14)

TOD:	119249537(HSD17B14)

TMU:

101355975

ETF:	101649846(HSD17B14)

DNM:	101434059(HSD17B14)

GAS:

123255204

SHR:	116422691(HSD17B14)

AFZ:

127556573

PCW:	110219697(HSD17B14)

TVP:	118839769(HSD17B14)

PBRV:

138173364(HSD17B14)

MLAO:

141509915(HSD17B14)

OAA:	103169720(HSD17B14)

TACU:

119933234(HSD17B14)

ASN:	102377059(HSD17B14)

AMJ:	102573913(HSD17B14)

CPOO:

109320822(HSD17B14)

CCAY:

125627903(HSD17B14)

DCC:	119847231(HSD17B14)

CPIC:

101948853(HSD17B14)

CABI:

116840045(HSD17B14)

MRV:	120388337(HSD17B14)

ACS:	100563880 103280323

ASAO:

132777919 132777920

PVT:

110078579

SUND:

121934227(HSD17B14)

PBI:

103058978

PMUR:

107282486(HSD17B14)

CTIG:

120304518(HSD17B14)

TSR:	106538707(HSD17B14)

PGUT:

117669105(HSD17B14)

APRI:

131198471(HSD17B14)

PTEX:

113443531(HSD17B14)

NSS:	113418536(HSD17B14)

VKO:	123032290(HSD17B14)

PMUA:

114581497(HSD17B14)

PRAF:

128400988(HSD17B14)

ZVI:	118094360(HSD17B14)

HCG:	128329907(HSD17B14)

GJA:

107105644

STOW:

125445304

EMC:

129339518

XLA:	100189572(hsd17b14.L)

XTR:	100498205(hsd17b14)

NPR:	108794948(HSD17B14)

RTEM:

120915316(HSD17B14)

BBUF:

121003301(HSD17B14)

BGAR:

122928565(HSD17B14)

PWL:	138246271(HSD17B14)

MUO:	115466538(HSD17B14)

GSH:	117367522(HSD17B14)

DRE:	445127(hsd17b14)

SRX:	107729477 107732853

SANH:

107680856(hsd17b14)

SGH:	107551148 107561364

CAUA:

113046701 113047023

CGIB:

127949039 127953673

LROH:

127163178(hsd17b14)

OMC:	131535990(hsd17b14)

PPRM:

120489462(hsd17b14)

RKG:	130078615(hsd17b14)

MASI:

127451916

TROS:

130561645(hsd17b14)

TDW:	130426304(hsd17b14)

MANU:

129436144(hsd17b14)

PDAB:

135769075(hsd17b14)

IPU:

108278811

IFU:	128603691(hsd17b14)

PHYP:

113527940(hsd17b14)

SMEO:

124396733(hsd17b14)

TFD:	113663931(hsd17b14)

TVC:	132860641(hsd17b14)

CGAR:

128545101(hsd17b14)

NGRA:

132868928(hsd17b14)

TRN:	134300259(hsd17b14)

AMEX:

103039867(hsd17b14)

CMAO:

118821140(hsd17b14)

EEE:	113587149(hsd17b14)

CHAR:

116218339(hsd17b14)

SPIL:

134076606(hsd17b14)

ASAD:

121706110(hsd17b14)

TRU:	101066419(hsd17b14)

TFS:	130515550(hsd17b14)

LCO:

104931290

PGEO:

117450870(hsd17b14)

GACU:

117548402(hsd17b14)

ELY:	117267822(hsd17b14)

PLEP:

121956471(hsd17b14)

SLUC:

116063828(hsd17b14)

ECRA:

117957599(hsd17b14)

ESP:

116703804

PFLV:

114569115

GAT:	120827443(hsd17b14)

PPUG:

119220381(hsd17b14)

AFB:	129098407(hsd17b14)

CLUM:

117735259(hsd17b14)

CANA:

137787123(hsd17b14)

CVE:	137884096(hsd17b14)

MSAM:

119894112(hsd17b14)

SCHU:

122869183(hsd17b14)

CUD:	121529435(hsd17b14)

SPUL:

138604255(hsd17b14)

LMIX:

132995725(hsd17b14)

ALAT:

119013282(hsd17b14)

MZE:	101485360(hsd17b14)

ONL:	100711283(hsd17b14)

OAU:	116329087(hsd17b14)

OLA:	101168290(hsd17b14)

OML:	112146040(hsd17b14)

XMA:	102238340(hsd17b14)

PPRL:

129373747(hsd17b14)

CVG:	107097104(hsd17b14)

CTUL:

119789971(hsd17b14)

GMU:	124862624 124864195

NFU:	107378440(hsd17b14)

ALIM:

106524817(hsd17b14)

NWH:	119421324(hsd17b14)

AOCE:

111572734(hsd17b14)

EJA:	138207820(hsd17b14)

BFRE:

138627074(hsd17b14)

CSEM:

103392551

SSOE:

131475106(hsd17b14)

HSP:	124851073(hsd17b14)

PPLT:

128458996(hsd17b14)

SMAU:

124849439(hsd17b14)

SDU:	111217584(hsd17b14)

SLAL:

111660520(hsd17b14)

ENY:	140358064(hsd17b14)

MALB:

109963112(hsd17b14)

BSPL:

114860597(hsd17b14)

SJO:	128378960(hsd17b14)

SSCO:

133999640(hsd17b14)

TTY:	137167863(hsd17b14)

GMH:	115530929(hsd17b14)

SASA:

100195824(dhb14) 106593760 106606926

STRU:

115171476 115203025

OTW:	112234086 112237353

OMY:	110486643 110538601

OGO:	123999371 124015650

ONE:	115121666 115126931

OKI:	109898703 109898704(hsd17b14)

OKE:

118371525

OCLA:

139364986 139421467

SALP:

111980722 111980723

SNH:	120034208 120044648

SFON:

129825011 129833456

CCLU:

121568937

ELS:	105012930(hsd17b14)

OEP:	134036466(hsd17b14)

AANG:

118217263(hsd17b14)

AROT:

135243245(hsd17b14)

CCOG:

133114583 133115213(hsd17b14)

LCM:	102366834(HSD17B14)

PMRN:

116944461(HSD17B14)

LRJ:	133341778 133342670

BFO:

BBEL:

SCLV:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:

PFLL:

LGI:	LOTGIDRAFT_208963 LOTGIDRAFT_228365

PVUL:

PCAN:

LSAX:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

YBA:	132552257 132552273

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

LJP:

LAK:

LLON:

NVE:	5507030 5509014

EPA:

ATEN:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

SRE:	PTSG_00704

AAF:	AURANDRAFT_28663

» show all

Reference

PMID:38944119

Authors

Witecka A, Kazak V, Kwiatkowski S, Kiersztan A, Jagielski AK, Kozminski W, Augustyniak R, Drozak J

Title

Hydroxysteroid 17-beta dehydrogenase 14 (HSD17B14) is an L-fucose dehydrogenase, the initial enzyme of the L-fucose degradation pathway.

Journal

J Biol Chem 300:107501 (2024)
DOI:10.1016/j.jbc.2024.107501

Sequence

[hsa:51171]

LinkDB

DBGET integrated database retrieval system