KEGG   ORTHOLOGY: K28725
Entry
K28725                      KO                                     
Symbol
sktA
Name
5-bromoskatole synthase [EC:1.3.3.18]
Pathway
map00997  Biosynthesis of various other secondary metabolites
map01110  Biosynthesis of secondary metabolites
Reaction
R13634  5-bromo-L-tryptophan:oxygen oxidoreductase (5-bromoskatole forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00997 Biosynthesis of various other secondary metabolites
    K28725  sktA; 5-bromoskatole synthase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.3  With oxygen as acceptor
    1.3.3.18  5-bromoskatole synthase
     K28725  sktA; 5-bromoskatole synthase
Genes
AGE: AA314_00614
AMR: AM1_0779
KOV: K9N68_07115
LSK: J5X98_06365
NOP: Nos7524_0514
NON: NOS3756_43580
NOE: CLI64_11835 CLI64_21160
NCW: NIES2107_04380
NOSU: JYQ62_03190
NOSZ: WKK05_31730
NOSC: L6494_24320
NAZ: Aazo_0025
CSG: Cylst_1481
HBQ: QI031_11940
ALIH: ACQFX9_06655 ACQFX9_08775 ACQFX9_24965
AMAT: ACPZ3T_05945
CALO: Cal7507_4675
CALT: Cal6303_0465
CALS: NIES3974_46710
RIV: Riv7116_6446
MDP: NIES3275_52060
TTQ: NIES37_01130
TOI: HG267_16030
TOZ: HGR01_02745
ALAX: NIES50_18710
SCYT: SAMD_23540
SCYS: NIES4073_72900
NCN: BZZ01_19035
GLP: Glo7428_1249
AG: RCJ35217(sktA)
 » show all
Reference
PMID:39939147
  Authors
Adak S, Calderone LA, Krueger A, Pandelia ME, Moore BS.
  Title
Single-Enzyme Conversion of Tryptophan to Skatole and Cyanide Expands the Mechanistic Competence of Diiron Oxidases.
  Journal
J Am Chem Soc 147:6326-6331 (2025)
DOI:10.1021/jacs.4c14573
  Sequence
[ag:RCJ35217]
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