KEGG   ORTHOLOGY: K28874
Entry
K28874                      KO                                     
Symbol
spmT
Name
sphingomyelin phosphodiesterase [EC:3.1.4.12]
Pathway
map00600  Sphingolipid metabolism
map01100  Metabolic pathways
Reaction
R02541  sphingomyelin cholinephosphohydrolase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00600 Sphingolipid metabolism
    K28874  spmT; sphingomyelin phosphodiesterase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.12  sphingomyelin phosphodiesterase
     K28874  spmT; sphingomyelin phosphodiesterase
Other DBs
COG: COG3021
GO: 0004767
Genes
MTU: Rv0888
MTV: RVBD_0888
MTC: MT0911
MRA: MRA_0896
MTF: TBFG_10907
MTB: TBMG_03100
MTK: TBSG_03120
MTZ: TBXG_003079
MTI: MRGA423_05565
MTO: MTCTRI2_0911
MTD: UDA_0888
MTN: ERDMAN_0983
MTUB: MT7199_0907
MTUC: J113_06225
MTUE: J114_04730
MTX: M943_04640
MTUH: I917_06240
MTUL: TBHG_00876
MBO: BQ2027_MB0912
MBB: BCG_0940
MBT: JTY_0910
MBM: BCGMEX_0911
MBK: K60_009490
MBX: BCGT_0696
MAF: MAF_08970
MMIC: RN08_0987
MCE: MCAN_08891
MCQ: BN44_10971
MCV: BN43_20345
MCX: BN42_20674
MCZ: BN45_20180
MMI: MMAR_4644
MMAE: MMARE11_44690
MLI: MULP_04859
MSHO: MSHO_56980(spmT)
MKN: MKAN_09410
MBAI: MB901379_04051
MLJ: MLAC_22670(spmT)
MSHJ: MSHI_09820
MOT: LTS72_02100
 » show all
Reference
PMID:26036301
  Authors
Speer A, Sun J, Danilchanka O, Meikle V, Rowland JL, Walter K, Buck BR, Pavlenok M, Holscher C, Ehrt S, Niederweis M
  Title
Surface hydrolysis of sphingomyelin by the outer membrane protein Rv0888 supports replication of Mycobacterium tuberculosis in macrophages.
  Journal
Mol Microbiol 97:881-97 (2015)
DOI:10.1111/mmi.13073
  Sequence
[mtu:Rv0888]
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