KEGG   MODULE: M00714
Entry
M00714            Signature Module                                 
Name
Multidrug resistance, efflux pump QacA
Definition
K18938 K08167
Diagram
M00714  Multidrug resistance, efflux pump QacA
M00714

Class
Signature modules; Gene set; Drug resistance
Orthology
K18938  
qacR; TetR/AcrR family transcriptional regulator, repressor for qacA
K08167  
smvA; MFS transporter, DHA2 family, multidrug resistance protein
Complete
sav  Staphylococcus aureus subsp. aureus Mu50 (MRSA/VISA)
suk  Staphylococcus aureus subsp. aureus JKD6008 (MRSA/VISA)
suw  Staphylococcus aureus subsp. aureus TW20 (MRSA)
sauz  Staphylococcus aureus subsp. aureus Z172 (MRSA/VISA)
saut  Staphylococcus aureus subsp. aureus ST228/10388 (MRSA)
sauj  Staphylococcus aureus subsp. aureus ST228/10497 (MRSA)
sauk  Staphylococcus aureus subsp. aureus ST228/15532 (MRSA)
sauq  Staphylococcus aureus subsp. aureus ST228/16035 (MRSA)
sauv  Staphylococcus aureus subsp. aureus ST228/18412 (MRSA)
saux  Staphylococcus aureus subsp. aureus ST228/18341 (MRSA)
sauy  Staphylococcus aureus subsp. aureus ST228/18583 (MRSA)
suh  Staphylococcus argenteus
shh  Staphylococcus haemolyticus Sh29/312/L2
 » show all
Reference
PMID:9660841
  Authors
Grkovic S, Brown MH, Roberts NJ, Paulsen IT, Skurray RA
  Title
QacR is a repressor protein that regulates expression of the Staphylococcus aureus multidrug efflux pump QacA.
  Journal
J Biol Chem 273:18665-73 (1998)
DOI:10.1074/jbc.273.29.18665
Reference
  Authors
Costa SS, Viveiros M, Amaral L, Couto I
  Title
Multidrug Efflux Pumps in Staphylococcus aureus: an Update.
  Journal
Open Microbiol J 7:59-71 (2013)
DOI:10.2174/1874285801307010059
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