KEGG   MODULE: M00718
Entry
M00718            Signature Module                                 
Name
Multidrug resistance, efflux pump MexAB-OprM
Definition
K18131 K03585+K18138+K18139
Diagram
M00718  Multidrug resistance, efflux pump MexAB-OprM
M00718

Class
Signature modules; Gene set; Drug resistance
Orthology
K18131  
mexR; MarR family transcriptional regulator, repressor of the mexAB-oprM multidrug resistance operon
K03585  
acrA; membrane fusion protein, multidrug efflux system
K18138  
acrB; multidrug efflux pump
K18139  
oprM; outer membrane protein, multidrug efflux system
Complete
gkn  Gallaecimonas kandeliae
pae  Pseudomonas aeruginosa PAO1
paev  Pseudomonas aeruginosa PAO1-VE13
paei  Pseudomonas aeruginosa PAO1-VE2
pau  Pseudomonas aeruginosa UCBPP-PA14
pag  Pseudomonas aeruginosa LESB58
paf  Pseudomonas aeruginosa M18
pnc  Pseudomonas aeruginosa NCGM2.S1
paeb  Pseudomonas aeruginosa NCGM 1900
pdk  Pseudomonas aeruginosa DK2
psg  Pseudomonas aeruginosa B136-33
prp  Pseudomonas aeruginosa RP73
paer  Pseudomonas aeruginosa PA1R
paem  Pseudomonas aeruginosa MTB-1
pael  Pseudomonas aeruginosa LES431
paes  Pseudomonas aeruginosa SCV20265
paeu  Pseudomonas aeruginosa PA38182
paeg  Pseudomonas aeruginosa YL84
paec  Pseudomonas aeruginosa c7447m
paeo  Pseudomonas aeruginosa PAO581
sech  Pseudomonas aeruginosa B18
pcq  Pseudomonas citronellolis
pmui  Pseudomonas multiresinivorans
pnt  Pseudomonas nitroreducens
pap  Pseudomonas paraeruginosa PA7
ppaa  Pseudomonas paraeruginosa
pdr  Pseudomonas sp. ATCC 13867
pkc  Pseudomonas knackmussii
ptrl  Pseudomonas triclosanedens
pden  Pseudomonas denitrificans (nom. rej.)
 » show all
Reference
PMID:11208776
  Authors
Evans K, Adewoye L, Poole K
  Title
MexR repressor of the mexAB-oprM multidrug efflux operon of Pseudomonas aeruginosa: identification of MexR binding sites in the mexA-mexR intergenic region.
  Journal
J Bacteriol 183:807-12 (2001)
DOI:10.1128/JB.183.3.807-812.2001
Reference
PMID:14734177
  Authors
Boutoille D, Corvec S, Caroff N, Giraudeau C, Espaze E, Caillon J, Plesiat P, Reynaud A
  Title
Detection of an IS21 insertion sequence in the mexR gene of Pseudomonas aeruginosa increasing beta-lactam resistance.
  Journal
FEMS Microbiol Lett 230:143-6 (2004)
DOI:10.1016/S0378-1097(03)00882-6
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