KEGG   MODULE: M00744
Entry
M00744            Signature Module                                 
Name
Cationic antimicrobial peptide (CAMP) resistance, protease PgtE
Definition
K07637 K07660 K08477
Diagram
M00744  Cationic antimicrobial peptide (CAMP) resistance, protease PgtE
M00744

Class
Signature modules; Gene set; Drug resistance
Orthology
K07637  
phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3] [COG:COG0642] [GO:0000155]
K07660  
phoP; two-component system, OmpR family, response regulator PhoP [COG:COG0745] [GO:0000156]
K08477  
pgtE; outer membrane protease E [EC:3.4.21.-] [COG:COG4571]
Complete
sty  Salmonella enterica subsp. enterica serovar Typhi CT18
stt  Salmonella enterica subsp. enterica serovar Typhi Ty2
sex  Salmonella enterica subsp. enterica serovar Typhi P-stx-12
sent  Salmonella enterica subsp. enterica serovar Typhi Ty21a
stm  Salmonella enterica subsp. enterica serovar Typhimurium LT2
seo  Salmonella enterica subsp. enterica serovar Typhimurium 14028S
sev  Salmonella enterica subsp. enterica serovar Typhimurium D23580
sey  Salmonella enterica subsp. enterica serovar Typhimurium SL1344
sem  Salmonella enterica subsp. enterica serovar Typhimurium T000240
sej  Salmonella enterica subsp. enterica serovar Typhimurium UK-1
seb  Salmonella enterica subsp. enterica serovar Typhimurium ST4/74
sef  Salmonella enterica subsp. enterica serovar Typhimurium 798
setu  Salmonella enterica subsp. enterica serovar Typhimurium U288
setc  Salmonella enterica subsp. enterica serovar Typhimurium var. 5- CFSAN001921
senr  Salmonella enterica subsp. enterica serovar Typhimurium DT2
send  Salmonella enterica subsp. enterica serovar Typhimurium DT104
seni  Salmonella enterica subsp. enterica serovar Typhimurium 138736
seen  Salmonella enterica subsp. enterica serovar 4,[5],12:i:- 08-1736
spt  Salmonella enterica subsp. enterica serovar Paratyphi A ATCC9150
sek  Salmonella enterica subsp. enterica serovar Paratyphi A AKU12601
spq  Salmonella enterica subsp. enterica serovar Paratyphi B
sei  Salmonella enterica subsp. enterica serovar Paratyphi C
sec  Salmonella enterica subsp. enterica serovar Choleraesuis
seh  Salmonella enterica subsp. enterica serovar Heidelberg SL476
shb  Salmonella enterica subsp. enterica serovar Heidelberg B182
senh  Salmonella enterica subsp. enterica serovar Heidelberg CFSAN002069
seeh  Salmonella enterica subsp. enterica serovar Heidelberg 41578
see  Salmonella enterica subsp. enterica serovar Newport SL254
senn  Salmonella enterica subsp. enterica serovar Newport USMARC-S3124.1
sew  Salmonella enterica subsp. enterica serovar Schwarzengrund
sea  Salmonella enterica subsp. enterica serovar Agona SL483
sens  Salmonella enterica subsp. enterica serovar Agona 24249
sed  Salmonella enterica subsp. enterica serovar Dublin
seg  Salmonella enterica subsp. enterica serovar Gallinarum 287/91
sel  Salmonella enterica subsp. enterica serovar Gallinarum/pullorum RKS5078
sega  Salmonella enterica subsp. enterica serovar Gallinarum/pullorum CDC1983-67
set  Salmonella enterica subsp. enterica serovar Enteritidis P125109
sena  Salmonella enterica subsp. enterica serovar Enteritidis EC20090135
seno  Salmonella enterica subsp. enterica serovar Enteritidis EC20090193
senv  Salmonella enterica subsp. enterica serovar Enteritidis EC20090332
senq  Salmonella enterica subsp. enterica serovar Enteritidis EC20090531
senl  Salmonella enterica subsp. enterica serovar Enteritidis OLF-SE1-1019-1
senj  Salmonella enterica subsp. enterica serovar Javiana
seec  Salmonella enterica subsp. enterica serovar Cubana
seeb  Salmonella enterica subsp. enterica serovar Bareilly
seep  Salmonella enterica subsp. enterica serovar Pullorum
senb  Salmonella enterica subsp. enterica serovar Bovismorbificans
sene  Salmonella enterica subsp. enterica serovar Thompson
senc  Salmonella enterica subsp. enterica serovar Tennessee
ses  Salmonella enterica subsp. arizonae
sbg  Salmonella bongori NCTC 12419
sbz  Salmonella bongori N268-08
sbv  Salmonella bongori serovar 48:z41:--
salz  Salmonella sp. SSDFZ69
ppao  Pseudomonas phytophila
 » show all
Comment
Resistance mechanism: cleavage of peptides
Reference
PMID:10869088
  Authors
Guina T, Yi EC, Wang H, Hackett M, Miller SI
  Title
A PhoP-regulated outer membrane protease of Salmonella enterica serovar typhimurium promotes resistance to alpha-helical antimicrobial peptides.
  Journal
J Bacteriol 182:4077-86 (2000)
DOI:10.1128/JB.182.14.4077-4086.2000
Reference
PMID:21149452
  Authors
Weatherspoon-Griffin N, Zhao G, Kong W, Kong Y, Morigen, Andrews-Polymenis H, McClelland M, Shi Y
  Title
The CpxR/CpxA two-component system up-regulates two Tat-dependent peptidoglycan amidases to confer bacterial resistance to antimicrobial peptide.
  Journal
J Biol Chem 286:5529-39 (2011)
DOI:10.1074/jbc.M110.200352
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