| Entry |
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| Name |
Cationic antimicrobial peptide (CAMP) resistance, protease PgtE
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| Definition |
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| Diagram |
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| Orthology |
phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC: 2.7.13.3] [COG: COG0642] [GO: 0000155] phoP; two-component system, OmpR family, response regulator PhoP [COG: COG0745] [GO: 0000156] pgtE; outer membrane protease E [EC:3.4.21.-] [COG: COG4571] |
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| Class |
Signature modules; Gene set; Drug resistance
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| Comment |
Resistance mechanism: cleavage of peptides
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| Reference |
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| Authors |
Guina T, Yi EC, Wang H, Hackett M, Miller SI |
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| Title |
A PhoP-regulated outer membrane protease of Salmonella enterica serovar typhimurium promotes resistance to alpha-helical antimicrobial peptides. |
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| Journal |
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| Reference |
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| Authors |
Weatherspoon-Griffin N, Zhao G, Kong W, Kong Y, Morigen, Andrews-Polymenis H, McClelland M, Shi Y |
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| Title |
The CpxR/CpxA two-component system up-regulates two Tat-dependent peptidoglycan amidases to confer bacterial resistance to antimicrobial peptide. |
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| Journal |
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| LinkDB |
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