KEGG   MODULE: M00836
Entry
M00836            Pathway   Module                                 
Name
Coenzyme F430 biosynthesis, sirohydrochlorin => coenzyme F430
Definition
K22011 K22012 (K21610+K21611) K21612
Diagram
M00836

Orthology
K22011  
cfbA; sirohydrochlorin nickelchelatase [EC:4.99.1.11] [RN:R11626]
K22012  
cfbB; Ni-sirohydrochlorin a,c-diamide synthase [EC:6.3.5.12] [RN:R11627]
cfbCD; nickel-sirohydrochlorin a,c-diamide reductase [EC:6.3.3.7] [RN:R11628]
K21612  
cfbE; coenzyme F430 synthetase [EC:6.4.1.9] [RN:R11629]
Class
Pathway modules; Metabolism of cofactors and vitamins; Cofactor and vitamin metabolism
Pathway
map00860  Porphyrin metabolism
map01240  Biosynthesis of cofactors
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Reaction
Compound
C05778  Sirohydrochlorin
C21510  Nickel-sirohydrochlorin
C21511  Nickel-sirohydrochlorin a,c-diamide
C21512  15,17(3)-Seco-F430-17(3)-acid
C05777  Coenzyme F430
Reference
  Authors
Zheng K, Ngo PD, Owens VL, Yang XP, Mansoorabadi SO
  Title
The biosynthetic pathway of coenzyme F430 in methanogenic and methanotrophic archaea.
  Journal
Science 354:339-342 (2016)
DOI:10.1126/science.aag2947
Reference
  Authors
Moore SJ, Sowa ST, Schuchardt C, Deery E, Lawrence AD, Ramos JV, Billig S, Birkemeyer C, Chivers PT, Howard MJ, Rigby SE, Layer G, Warren MJ
  Title
Elucidation of the biosynthesis of the methane catalyst coenzyme F430.
  Journal
Nature 543:78-82 (2017)
DOI:10.1038/nature21427
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