KEGG   MODULE: M00845
Entry
M00845            Pathway   Module                                 
Name
Arginine biosynthesis, glutamate => acetylcitrulline => arginine
Definition
K22478 K00145 K00821 K09065 K01438 K01940 K01755
Diagram
M00845

Orthology
K22478  
K22478; bifunctional N-acetylglutamate synthase/kinase [EC:2.3.1.1 2.7.2.8] [RN:R00259 R02649]
K00145  
argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38] [RN:R03443]
K00821  
argD; acetylornithine aminotransferase [EC:2.6.1.11] [RN:R02283]
K09065  
argF; N-acetylornithine carbamoyltransferase [EC:2.1.3.9] [RN:R07245]
K01438  
argE; acetylornithine deacetylase [EC:3.5.1.16] [RN:R09107]
K01940  
argG; argininosuccinate synthase [EC:6.3.4.5] [RN: R01954]
K01755  
argH; argininosuccinate lyase [EC:4.3.2.1] [RN:R01086]
Class
Pathway modules; Amino acid metabolism; Arginine and proline metabolism
Pathway
map00220  Arginine biosynthesis
map01230  Biosynthesis of amino acids
map01100  Metabolic pathways
Reaction
R00259  
R02649  
R03443  
R02283  
R07245  
R09107  
R01954  
R01086  
Compound
C00025  L-Glutamate
C00624  N-Acetyl-L-glutamate
C04133  N-Acetyl-L-glutamate 5-phosphate
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C00437  N-Acetylornithine
C00169  Carbamoyl phosphate
C15532  N-Acetyl-L-citrulline
C00327  L-Citrulline
C00049  L-Aspartate
C03406  N-(L-Arginino)succinate
C00062  L-Arginine
C00122  Fumarate
Reference
PMID:16585758
  Authors
Morizono H, Cabrera-Luque J, Shi D, Gallegos R, Yamaguchi S, Yu X, Allewell NM, Malamy MH, Tuchman M
  Title
Acetylornithine transcarbamylase: a novel enzyme in arginine biosynthesis.
  Journal
J Bacteriol 188:2974-82 (2006)
DOI:10.1128/JB.188.8.2974-2982.2006
Reference
PMID:17347518
  Authors
Xu Y, Labedan B, Glansdorff N
  Title
Surprising arginine biosynthesis: a reappraisal of the enzymology and evolution of the pathway in microorganisms.
  Journal
Microbiol Mol Biol Rev 71:36-47 (2007)
DOI:10.1128/MMBR.00032-06
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