KEGG   MODULE: M00990
Entry
M00990            Pathway   Module                                 
Name
Dimethylsulfoniopropionate (DMSP) degradation, demethylation pathway, DMSP => methanethiol
Definition
K17486 K20034 K20035 K20036
Diagram
M00990  Dimethylsulfoniopropionate (DMSP) degradation, demethylation pathway, DMSP => methanethiol
M00990

Class
Pathway modules; Energy metabolism; Sulfur metabolism
Pathway
map00920  Sulfur metabolism
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Orthology
K17486  
dmdA; dimethylsulfoniopropionate demethylase [EC:2.1.1.269] [RN:R10333]
K20034  
dmdB; 3-(methylthio)propionyl---CoA ligase [EC:6.2.1.44] [RN:R10820]
K20035  
dmdC; 3-(methylsulfanyl)propanoyl-CoA dehydrogenase [EC:1.3.99.41] [RN:R11130]
K20036  
dmdD; (methylthio)acryloyl-CoA hydratase [EC:4.2.1.155] [RN:R10936]
Complete
hoe  Hoeflea sp. IMCC20628
hoax  Parahoeflea alexandrii
labr  Labrenzia sp. VG12
rpop  Roseibium porphyridii
sil  Ruegeria pomeroyi
jan  Jannaschia sp. CCS1
pga  Phaeobacter inhibens DSM 17395
phae  Phaeobacter sp. G2
lmd  Leisingera methylohalidivorans
lej  Leisingera sp. NJS204
lev  Leisingera sp. NJS201
leim  Leisingera sp. M523
sulz  Sulfitobacter sp. SK012
smed  Sulfitobacter mediterraneus
sual  Sulfitobacter albidus
tate  Tateyamaria algicola
taty  Tateyamaria rhodophyticola
aht  Antarctobacter heliothermus
lalg  Lentibacter algarum
maru  Palleronia sp. THAF1
asca  Aliisedimentitalea scapharcae
matg  Marivita sp. tig00000067
ppso  Parasedimentitalea psychrophila
gce  Gymnodinialimonas ceratoperidinii
gyj  Gymnodinialimonas sp. 57CJ19
amyl  Amylibacter sp. IMCC11727
amaq  Algicella marina
 » show all
Reaction
Compound
C04022  S,S-Dimethyl-beta-propiothetin
C08276  3-(Methylthio)propanoate
C20870  3-(Methylthio)propanoyl-CoA
C20955  3-(Methylthio)acryloyl-CoA
C00409  Methanethiol
C00084  Acetaldehyde
Reference
  Authors
Reisch CR, Stoudemayer MJ, Varaljay VA, Amster IJ, Moran MA, Whitman WB
  Title
Novel pathway for assimilation of dimethylsulphoniopropionate widespread in marine bacteria.
  Journal
Nature 473:208-11 (2011)
DOI:10.1038/nature10078
Reference
  Authors
Curson AR, Todd JD, Sullivan MJ, Johnston AW.
  Title
Catabolism of dimethylsulphoniopropionate: microorganisms, enzymes and genes.
  Journal
Nat Rev Microbiol 9:849-59 (2011)
DOI:10.1038/nrmicro2653
Reference
  Authors
He X-Y, Liu N-H, Liu J-Q, Peng M, Teng Z-J, Gu T-J, Chen X-L, Chen Y, Wang P, Li C-Y, Todd JD, Zhang Y-Z, Zhang X-Y.
  Title
SAR92 clade bacteria are potentially important DMSP degraders and sources of  climate-active gases in marine environments.
  Journal
mBio 14:e0146723 (2023)
DOI:10.1128/mbio.01467-23
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