KEGG   MODULE: M01023
Entry
M01023            Pathway   Module                                 
Name
dTDP-D-Fuc3NAc biosynthesis, Glc-1P => dTDP-D-Fuc3NAc
Definition
K00973 K01710 K20679 K20680 K20681
Diagram
M01023  dTDP-D-Fuc3NAc biosynthesis, Glc-1P => dTDP-D-Fuc3NAc
M01023

Class
Pathway modules; Glycan metabolism; Nucleotide sugar biosynthesis
Pathway
map00541  Biosynthesis of various nucleotide sugars
map00523  Polyketide sugar unit biosynthesis
map01250  Biosynthesis of nucleotide sugars
map01100  Metabolic pathways
Orthology
K00973  
rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] [RN:R02328]
K01710  
rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] [RN:R06513]
K20679  
fdtA; TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase [EC:5.3.2.3] [RN:R09904]
K20680  
fdtB; dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose transaminase [EC:2.6.1.90] [RN:R09824]
K20681  
fdtC; dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase [EC:2.3.1.197] [RN:R09873]
Complete
143495  Aneurinibacillus thermoaerophilus
Reaction
R02328  
R06513  
R09904  
R09824  
R09873  
Compound
C00103  D-Glucose 1-phosphate
C00842  dTDP-glucose
C11907  dTDP-4-oxo-6-deoxy-D-glucose
C19960  dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose
C19947  dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose
C20156  dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactopyranose
RModule
RM043  Transamination and N-acetylation in deoxysugar biosynthesis
Reference
PMID:12740380
  Authors
Pfoestl A, Hofinger A, Kosma P, Messner P
  Title
Biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactose in Aneurinibacillus thermoaerophilus L420-91T.
  Journal
J Biol Chem 278:26410-7 (2003)
DOI:10.1074/jbc.M300858200
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