KEGG   MODULE: M01031
Entry
M01031            Pathway   Module                                 
Name
CDP-Asc biosynthesis, Glc-1P => CDP-Asc
Definition
K00978 K01709 K12452+K00523 K15857 K15858
Diagram
M01031  CDP-Asc biosynthesis, Glc-1P => CDP-Asc
M01031

Class
Pathway modules; Glycan metabolism; Nucleotide sugar biosynthesis
Pathway
map00541  Biosynthesis of various nucleotide sugars
map01250  Biosynthesis of nucleotide sugars
map01100  Metabolic pathways
Orthology
K00978  
ascA; glucose-1-phosphate cytidylyltransferase [EC:2.7.7.33] [RN:R00956]
K01709  
ascB; CDP-glucose 4,6-dehydratase [EC:4.2.1.45] [RN:R02426]
K12452,K00523  
ascCD; CDP-4-dehydro-6-deoxyglucose reductase [EC:1.17.1.1] [RN:R03391 R03392]
K15857  
ascE; CDP-3, 6-dideoxy-D-glycero-D-glycero-4-hexulose-5-epimerase [EC:5.1.-.-] [RN:R08708]
K15858  
ascF; CDP-3, 6-dideoxy-D-glycero-L-glycero-4-hexulose-4-reductase [EC:1.1.1.-] [RN:R08709 R08710]
Complete
633  Yersinia pseudotuberculosis
Reaction
R00956  
R02426  
R03391,R03392  
R08708  
R08709,R08710  
Compound
C00103  D-Glucose 1-phosphate
C00501  CDP-glucose
C01219  CDP-4-dehydro-6-deoxy-D-glucose
C04297  CDP-4-dehydro-3,6-dideoxy-D-glucose
C17326  CDP-4-dehydro-3,6-dideoxy-D-glucose epimer
C17327  CDP-ascarylose
Reference
PMID:8071227
  Authors
Thorson JS, Lo SF, Ploux O, He X, Liu HW
  Title
Studies of the biosynthesis of 3,6-dideoxyhexoses: molecular cloning and characterization of the asc (ascarylose) region from Yersinia pseudotuberculosis serogroup VA.
  Journal
J Bacteriol 176:5483-93 (1994)
DOI:10.1128/JB.176.17.5483-5493.1994
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