KEGG   MODULE: M01043
Entry
M01043            Pathway   Module                                 
Name
Okenone biosynthesis, bacteria, lycopene => okenone
Definition
K06443 K09844 K25073 K09846 K25074
Diagram
M01043  Okenone biosynthesis, bacteria, lycopene => okenone
M01043

Class
Pathway modules; Biosynthesis of terpenoids and polyketides; Terpenoid biosynthesis
Pathway
map00906  Carotenoid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Orthology
K06443  
crtY; lycopene beta-cyclase [EC:5.5.1.19] [RN:R05341]
K09844  
crtC; carotenoid 1,2-hydratase [EC:4.2.1.131] [RN:R07516]
K25073  
cruO; 1'-hydroxy-gamma-carotene C-4' ketolase [RN:R12752]
K09846  
crtF; demethylspheroidene O-methyltransferase [EC:2.1.1.210] [RN:R12753]
K25074  
crtU; carotenoid chi-ring synthase [EC:1.3.99.40] [RN:R07849]
Complete
mpur  Marichromatium purpuratum
tsy  Thiodictyon syntrophicum
thip  Thiohalocapsa sp. PB-PSB1
thim  Thiocapsa sp. M50B4
Reaction
Compound
C05432  Lycopene
C05435  gamma-Carotene
C15859  1'-Hydroxy-gamma-carotene
C22346  1'-Hydroxy-1',2'-dihydro-beta,psi-caroten-4'-one
C16279  Thiothece-474
C16280  Okenone
Reference
  Authors
Vogl K, Bryant DA.
  Title
Elucidation of the biosynthetic pathway for Okenone in Thiodictyon sp. CAD16 leads to the discovery of two novel carotene ketolases.
  Journal
J Biol Chem 286:38521-32 (2011)
DOI:10.1074/jbc.M111.280131
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