| Entry |
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| Name |
Mutation-activated CDK4 to cell cycle G1/S
|
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| Definition |
(CCND+CDK4*) -> RB1 // E2F |
|---|
| Expanded |
((595,894,896)+1019v2) -> 5925 // (1869,1870,1871) |
|---|
| Class |
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|---|
| Type |
Variant
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| Pathway |
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|---|
| Disease |
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|---|
| Gene |
| 1019 | CDK4; cyclin dependent kinase 4 |
| 5925 | RB1; RB transcriptional corepressor 1 |
| 1869 | E2F1; E2F transcription factor 1 |
| 1870 | E2F2; E2F transcription factor 2 |
| 1871 | E2F3; E2F transcription factor 3 |
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|---|
| Variant |
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|---|
| Reference |
|
|---|
| Authors |
Miller AJ, Mihm MC Jr. |
|---|
| Title |
Melanoma. |
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| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Chudnovsky Y, Khavari PA, Adams AE. |
|---|
| Title |
Melanoma genetics and the development of rational therapeutics. |
|---|
| Journal |
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| LinkDB |
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