KEGG   NETWORK: N00108
Entry
N00108                      Network                                
Name
AML1-ETO fusion to transcriptional activtion
Definition
AML1-ETO => JUP
  Expanded
861v2 => 3728
Class
nt06275 Acute myeloid leukemia
nt06240 Transcription (cancer)
Type
Variant
Pathway
hsa05221  Acute myeloid leukemia
Disease
H00003  Acute myeloid leukemia
Gene
861  RUNX1; runt related transcription factor 1
3728  JUP; junction plakoglobin
Variant
861v2 (AML1-ETO)  AML1-ETO fusion
Reference
PMID:15024077
  Authors
Muller-Tidow C, Steffen B, Cauvet T, Tickenbrock L, Ji P, Diederichs S, Sargin B, Kohler G, Stelljes M, Puccetti E, Ruthardt M, deVos S, Hiebert SW, Koeffler HP, Berdel WE, Serve H
  Title
Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells.
  Journal
Mol Cell Biol 24:2890-904 (2004)
DOI:10.1128/MCB.24.7.2890-2904.2004
Reference
PMID:16236521
  Authors
Steffen B, Muller-Tidow C, Schwable J, Berdel WE, Serve H.
  Title
The molecular pathogenesis of acute myeloid leukemia.
  Journal
Crit Rev Oncol Hematol 56:195-221 (2005)
DOI:10.1016/j.critrevonc.2004.10.012
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