| Entry |
|
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| Name |
AML1-ETO fusion to CEBPA-mediated transcription
|
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| Definition |
AML1-ETO -| CEBPA => PER2 |
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| Expanded |
861v2 -| 1050 => 8864 |
|---|
| Class |
|
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| Type |
Variant
|
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| Pathway |
|
|---|
| Disease |
|
|---|
| Gene |
| 861 | RUNX1; runt related transcription factor 1 |
| 1050 | CEBPA; CCAAT/enhancer binding protein alpha |
| 8864 | PER2; period circadian clock 2 |
|
|---|
| Variant |
861v2 (AML1-ETO) AML1-ETO fusion
|
|---|
| Reference |
|
|---|
| Authors |
Scandura JM, Boccuni P, Cammenga J, Nimer SD |
|---|
| Title |
Transcription factor fusions in acute leukemia: variations on a theme. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Lutterbach B, Hiebert SW |
|---|
| Title |
Role of the transcription factor AML-1 in acute leukemia and hematopoietic differentiation. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Koschmieder S, Halmos B, Levantini E, Tenen DG |
|---|
| Title |
Dysregulation of the C/EBPalpha differentiation pathway in human cancer. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Gery S, Gombart AF, Yi WS, Koeffler C, Hofmann WK, Koeffler HP |
|---|
| Title |
Transcription profiling of C/EBP targets identifies Per2 as a gene implicated in myeloid leukemia. |
|---|
| Journal |
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|---|
| LinkDB |
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