NETWORK: N00138
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Entry
N00138 Network
Name
EWSR1-NR4A3
Definition
EWSR-NR4A3 => PPARG
Expanded
8013v1 => 5468
Class
nt06240
Transcription
Type
Variant
Disease
H00053
Extraskeletal myxoid chondrosarcoma
Gene
8013
NR4A3; nuclear receptor subfamily 4 group A member 3
5468
PPARG; peroxisome proliferator activated receptor gamma
Variant
8013v1
(EWSR-NR4A3) EWSR1-NR4A3 fusion
Reference
PMID:
18855877
Authors
Filion C, Motoi T, Olshen AB, Lae M, Emnett RJ, Gutmann DH, Perry A, Ladanyi M, Labelle Y
Title
The EWSR1/NR4A3 fusion protein of extraskeletal myxoid chondrosarcoma activates the PPARG nuclear receptor gene.
Journal
J Pathol 217:83-93 (2009)
DOI:
10.1002/path.2445
Reference
PMID:
22567356
Authors
Nishio J, Iwasaki H, Nabeshima K, Naito M
Title
Cytogenetics and molecular genetics of myxoid soft-tissue sarcomas.
Journal
Genet Res Int 2011:497148 (2011)
DOI:
10.4061/2011/497148
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