| Entry |
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| Name |
TGFBR2-reduced expression to TGF-beta signaling pathway
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| Definition |
(TGFBR2*+TGFBR1) // (SMAD2,SMAD3) |
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| Expanded |
(7048v2+7046) // (4087,4088) |
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| Class |
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| Type |
Variant
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| Pathway |
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| Disease |
| H00048 | Hepatocellular carcinoma |
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| Gene |
| 7048 | TGFBR2; transforming growth factor beta receptor 2 |
| 7046 | TGFBR1; transforming growth factor beta receptor 1 |
| 4087 | SMAD2; SMAD family member 2 |
| 4088 | SMAD3; SMAD family member 3 |
|
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| Variant |
7048v2 (TGFBR2*) TGFBR2 reduced expression
|
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| Reference |
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| Authors |
Breuhahn K, Longerich T, Schirmacher P |
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| Title |
Dysregulation of growth factor signaling in human hepatocellular carcinoma. |
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| Journal |
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| Reference |
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| Authors |
Achyut BR, Yang L |
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| Title |
Transforming growth factor-beta in the gastrointestinal and hepatic tumor microenvironment. |
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| Journal |
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| Reference |
|
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| Authors |
Musch A, Rabe C, Paik MD, Berna MJ, Schmitz V, Hoffmann P, Nischalke HD, Sauerbruch T, Caselmann WH |
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| Title |
Altered expression of TGF-beta receptors in hepatocellular carcinoma--effects of a constitutively active TGF-beta type I receptor mutant. |
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| Journal |
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| LinkDB |
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