| Entry |
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| Name |
ESR1-positive to nuclear-initiated estrogen signaling pathway
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| Definition |
E2 -> (ESR*+(NCOA3,NCOA1)) => (CCND1,MYC) |
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| Expanded |
C00951 -> (2099v1+(8202,8648)) => (595,4609) |
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| Class |
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| Type |
Variant
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| Pathway |
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| Disease |
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| Gene |
| 2099 | ESR1; estrogen receptor 1 |
| 8202 | NCOA3; nuclear receptor coactivator 3 |
| 8648 | NCOA1; nuclear receptor coactivator 1 |
| 4609 | MYC; MYC proto-oncogene, bHLH transcription factor |
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| Variant |
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| Metabolite |
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| Reference |
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| Authors |
Wu VS, Kanaya N, Lo C, Mortimer J, Chen S |
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| Title |
From bench to bedside: What do we know about hormone receptor-positive and human epidermal growth factor receptor 2-positive breast cancer? |
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| Journal |
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| Reference |
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| Authors |
Butt AJ, McNeil CM, Musgrove EA, Sutherland RL |
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| Title |
Downstream targets of growth factor and oestrogen signalling and endocrine resistance: the potential roles of c-Myc, cyclin D1 and cyclin E. |
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| Journal |
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| Reference |
|
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| Authors |
Zhang MH, Man HT, Zhao XD, Dong N, Ma SL |
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| Title |
Estrogen receptor-positive breast cancer molecular signatures and therapeutic potentials (Review). |
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| Journal |
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| Reference |
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| Authors |
Dasgupta S, Lonard DM, O'Malley BW |
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| Title |
Nuclear receptor coactivators: master regulators of human health and disease. |
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| Journal |
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| Reference |
|
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| Authors |
Manavathi B, Samanthapudi VS, Gajulapalli VN |
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| Title |
Estrogen receptor coregulators and pioneer factors: the orchestrators of mammary gland cell fate and development. |
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| Journal |
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| LinkDB |
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