KEGG   NETWORK: N00490
Entry
N00490                      Network                                
Name
HTLV-1 p12 to calcineurin signaling pathway
Definition
P12 == (CALR,CANX) -> Ca2+
  Expanded
K23069 == (811,821) -> C00076
Class
nt06537 TCR/BCR signaling
nt06220 Calcium signaling (cancer)
nt06160 Human T-cell leukemia virus 1 (HTLV-1)
Type
Pathogen
Pathway
hsa05166  Human T-cell leukemia virus 1 infection
Disease
H00009  Adult T-cell leukemia
Gene
811  CALR; calreticulin
821  CANX; calnexin
Perturbant
K23069 (P12)  p12I; HTLV-1 accessory protein p12I
Metabolite
C00076  Calcium cation
Reference
PMID:21994758
  Authors
Edwards D, Fenizia C, Gold H, de Castro-Amarante MF, Buchmann C, Pise-Masison CA, Franchini G
  Title
Orf-I and orf-II-encoded proteins in HTLV-1 infection and persistence.
  Journal
Viruses 3:861-85 (2011)
DOI:10.3390/v3060861
Reference
  Authors
Sinet F.
  Title
Complex splicing in the human T-cell leukemia virus (HTLV) family of retroviruses: a number of proteins play a key role in the establishment and maintenance of viral infection.
  Journal
BioSciences Master Reviews, July 2013
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