| Entry |
|
| Name |
HCV NS5A to TNF-NFKB signaling pathway
|
| Definition |
NS5A -| (TRADD+TRAF2) |
| Expanded |
K22275 -| (8717+7186) |
| Class |
|
| Type |
Pathogen
|
| Pathway |
|
| Disease |
| H00048 | Hepatocellular carcinoma |
|
| Gene |
| 8717 | TRADD; TNFRSF1A associated via death domain |
| 7186 | TRAF2; TNF receptor associated factor 2 |
|
| Perturbant |
| K22275 (NS5A) | NS5A; HCV non-structural protein 5A |
|
| Reference |
|
| Authors |
Park KJ, Choi SH, Lee SY, Hwang SB, Lai MM |
| Title |
Nonstructural 5A protein of hepatitis C virus modulates tumor necrosis factor alpha-stimulated nuclear factor kappa B activation. |
| Journal |
|
| Reference |
|
| Authors |
Majumder M, Ghosh AK, Steele R, Zhou XY, Phillips NJ, Ray R, Ray RB |
| Title |
Hepatitis C virus NS5A protein impairs TNF-mediated hepatic apoptosis, but not by an anti-FAS antibody, in transgenic mice. |
| Journal |
|
| LinkDB |
|