Entry |
|
Name |
HCV NS5A to TNF-NFKB signaling pathway
|
Definition |
NS5A -| (TRADD+TRAF2) |
Expanded |
K22275 -| (8717+7186) |
Class |
|
Type |
Pathogen
|
Pathway |
|
Disease |
H00048 | Hepatocellular carcinoma |
|
Gene |
8717 | TRADD; TNFRSF1A associated via death domain |
7186 | TRAF2; TNF receptor associated factor 2 |
|
Perturbant |
K22275 (NS5A) | NS5A; HCV non-structural protein 5A |
|
Reference |
|
Authors |
Park KJ, Choi SH, Lee SY, Hwang SB, Lai MM |
Title |
Nonstructural 5A protein of hepatitis C virus modulates tumor necrosis factor alpha-stimulated nuclear factor kappa B activation. |
Journal |
|
Reference |
|
Authors |
Majumder M, Ghosh AK, Steele R, Zhou XY, Phillips NJ, Ray R, Ray RB |
Title |
Hepatitis C virus NS5A protein impairs TNF-mediated hepatic apoptosis, but not by an anti-FAS antibody, in transgenic mice. |
Journal |
|
LinkDB |
|