KEGG   NETWORK: N00685
Entry
N00685                      Network                                
Name
MV V to RIG-I-IRF7/3 signaling pathway
Definition
V -| IFIH1 -> MAVS
  Expanded
K22281 -| 64135 -> 57506
Class
nt06133 RLR signaling (viruses)
nt06169 Measles virus (MV)
Type
Pathogen
Pathway
hsa05162  Measles
Disease
H00394  Measles
Gene
64135  IFIH1; interferon induced with helicase C domain 1
57506  MAVS; mitochondrial antiviral signaling protein
Perturbant
K22281 (V)  V; measles non-structural protein V
Reference
  Authors
Jiang Y, Qin Y, Chen M
  Title
Host-Pathogen Interactions in Measles Virus Replication and Anti-Viral Immunity.
  Journal
Viruses 8:E308 (2016)
DOI:10.3390/v8110308
Reference
  Authors
Delpeut S, Noyce RS, Siu RW, Richardson CD
  Title
Host factors and measles virus replication.
  Journal
Curr Opin Virol 2:773-83 (2012)
DOI:10.1016/j.coviro.2012.10.008
Reference
  Authors
Andrejeva J, Childs KS, Young DF, Carlos TS, Stock N, Goodbourn S, Randall RE
  Title
The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter.
  Journal
Proc Natl Acad Sci U S A 101:17264-9 (2004)
DOI:10.1073/pnas.0407639101
Reference
  Authors
Childs K, Stock N, Ross C, Andrejeva J, Hilton L, Skinner M, Randall R, Goodbourn S
  Title
mda-5, but not RIG-I, is a common target for paramyxovirus V proteins.
  Journal
Virology 359:190-200 (2007)
DOI:10.1016/j.virol.2006.09.023
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